{
  "title": "Dose-handling reports by product form",
  "author": "HealthspanLedger",
  "edition": "2026.08",
  "version": "4ccde919bfa3",
  "page": "https://healthspanledger.com/dosing-errors",
  "citeAs": "HealthspanLedger. Dose-handling reports by product form, from FDA FAERS. Edition 2026.08 (version 4ccde919bfa3). Derived from FDA Adverse Event Reporting System (FAERS), openFDA drug event API, retrieved 2026-08-17. Licensed CC BY 4.0. https://healthspanledger.com/dosing-errors",
  "license": {
    "url": "https://creativecommons.org/licenses/by/4.0/",
    "name": "Creative Commons Attribution 4.0 International (CC BY 4.0)"
  },
  "arrangement": "The underlying records are United States government work and carry no copyright. How this table selects, joins, labels and bounds them is ours, and that work is licensed CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/): reuse it, including commercially, and credit HealthspanLedger with a link to the page it came from.",
  "source": {
    "name": "FDA Adverse Event Reporting System (FAERS) via openFDA",
    "endpoint": "https://api.fda.gov/drug/event.json",
    "retrieved": "2026-08-17",
    "dataLastUpdated": "2026-07-30",
    "license": "https://open.fda.gov/license/",
    "terms": "https://open.fda.gov/terms/",
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "queryStrategy": "Each drug's search unions openFDA's harmonised name fields (patient.drug.openfda.brand_name / generic_name) with the verbatim reported-product field (patient.drug.medicinalproduct), because the harmonisation is uneven: Wegovy has no openfda entry at all, and Ozempic and Rybelsus are both harmonised to the generic name 'ORAL SEMAGLUTIDE'. Clauses are joined with a spelled-out OR. Every stored searchExpression can be pasted into https://api.fda.gov/drug/event.json?search=<expr>&limit=1 to reproduce its total."
  },
  "readThisFirst": [
    "HealthspanLedger — dose-handling reports by product form",
    "Analysis by: HealthspanLedger",
    "Edition: 2026.08 (the month this reading was retrieved)",
    "Version: 4ccde919bfa3 (a digest of the rows below; it moves only when a value moves)",
    "Source: FDA Adverse Event Reporting System via openFDA, https://api.fda.gov/drug/event.json",
    "Retrieved: 2026-08-17 (FDA data last updated 2026-07-30)",
    "Source license (the federal records): https://open.fda.gov/license/ — US Government work, public domain",
    "This table's license (our selection and arrangement): https://creativecommons.org/licenses/by/4.0/ — Creative Commons Attribution 4.0 International (CC BY 4.0)",
    "The underlying records are United States government work and carry no copyright. How this table selects, joins, labels and bounds them is ours, and that work is licensed CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/): reuse it, including commercially, and credit HealthspanLedger with a link to the page it came from.",
    "Shares are shares of each drug’s own FAERS reports. They are NOT rates, and NOT shares of people who took the drug.",
    "FAERS has no denominator: nobody counted the people who took a drug and filed nothing.",
    "A report is not evidence the drug caused what was reported.",
    "Where incorrect_dose_share_is_upper_bound is true, the term is outside the drug’s 25 most-reported terms, so the share shown is a ceiling, not a measurement.",
    "FDA disclaimer: Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "Page: https://healthspanledger.com/dosing-errors",
    "Cite as: HealthspanLedger. Dose-handling reports by product form, from FDA FAERS. Edition 2026.08 (version 4ccde919bfa3). Derived from FDA Adverse Event Reporting System (FAERS), openFDA drug event API, retrieved 2026-08-17. Licensed CC BY 4.0. https://healthspanledger.com/dosing-errors"
  ],
  "termFamily": [
    "INCORRECT DOSE ADMINISTERED",
    "EXTRA DOSE ADMINISTERED",
    "ACCIDENTAL UNDERDOSE",
    "PRODUCT DOSE OMISSION ISSUE"
  ],
  "headlineTerm": "INCORRECT DOSE ADMINISTERED",
  "controlTerm": "NAUSEA",
  "storedTermCount": 25,
  "records": [
    {
      "drug": "Zepbound",
      "molecule": "tirzepatide",
      "application_holder": "Eli Lilly",
      "device_class": "You measure the dose yourself",
      "presentation": "single-dose pen, single-dose vial, and a multi-dose vial holding four 0.6 mL doses",
      "total_reports": 70141,
      "incorrect_dose_reports": 12768,
      "incorrect_dose_share_of_drug_reports": 0.182033,
      "incorrect_dose_share_is_upper_bound": false,
      "incorrect_dose_rank_among_stored_terms": 1,
      "nausea_reports": 7913,
      "nausea_share_of_drug_reports": 0.112816,
      "nausea_share_is_upper_bound": false,
      "dose_term_family_share_floor": 0.304729,
      "dose_term_family_share_ceiling": 0.304729,
      "dose_term_family_terms_outside_stored": 0,
      "serious_share_of_drug_reports": 0.089349,
      "twenty_fifth_stored_term_reports": 1313,
      "search_expression": "patient.drug.openfda.brand_name:\"ZEPBOUND\" OR patient.drug.medicinalproduct:\"ZEPBOUND\""
    },
    {
      "drug": "Mounjaro",
      "molecule": "tirzepatide",
      "application_holder": "Eli Lilly",
      "device_class": "You measure the dose yourself",
      "presentation": "single-dose pen, single-dose vial, and a multi-dose vial holding four 0.6 mL doses",
      "total_reports": 93975,
      "incorrect_dose_reports": 17026,
      "incorrect_dose_share_of_drug_reports": 0.181176,
      "incorrect_dose_share_is_upper_bound": false,
      "incorrect_dose_rank_among_stored_terms": 1,
      "nausea_reports": 9613,
      "nausea_share_of_drug_reports": 0.102293,
      "nausea_share_is_upper_bound": false,
      "dose_term_family_share_floor": 0.289503,
      "dose_term_family_share_ceiling": 0.289503,
      "dose_term_family_terms_outside_stored": 0,
      "serious_share_of_drug_reports": 0.25693,
      "twenty_fifth_stored_term_reports": 1611,
      "search_expression": "patient.drug.openfda.brand_name:\"MOUNJARO\" OR patient.drug.medicinalproduct:\"MOUNJARO\""
    },
    {
      "drug": "Egrifta SV",
      "molecule": "tesamorelin",
      "application_holder": "Theratechnologies",
      "device_class": "You measure the dose yourself",
      "presentation": "2 mg of dry powder in a single-dose vial, mixed with 10 mL of Sterile Water before use",
      "total_reports": 1500,
      "incorrect_dose_reports": 163,
      "incorrect_dose_share_of_drug_reports": 0.108667,
      "incorrect_dose_share_is_upper_bound": false,
      "incorrect_dose_rank_among_stored_terms": 2,
      "nausea_reports": null,
      "nausea_share_of_drug_reports": 0.022,
      "nausea_share_is_upper_bound": true,
      "dose_term_family_share_floor": 0.291333,
      "dose_term_family_share_ceiling": 0.335333,
      "dose_term_family_terms_outside_stored": 2,
      "serious_share_of_drug_reports": 0.205333,
      "twenty_fifth_stored_term_reports": 33,
      "search_expression": "patient.drug.openfda.brand_name:\"EGRIFTA SV\" OR patient.drug.medicinalproduct:\"EGRIFTA SV\""
    },
    {
      "drug": "Trulicity",
      "molecule": "dulaglutide",
      "application_holder": "Eli Lilly",
      "device_class": "It comes ready-measured",
      "presentation": "single-dose pen at 0.75, 1.5, 3 or 4.5 mg — one strength per pen",
      "total_reports": 88332,
      "incorrect_dose_reports": 5599,
      "incorrect_dose_share_of_drug_reports": 0.063386,
      "incorrect_dose_share_is_upper_bound": false,
      "incorrect_dose_rank_among_stored_terms": 6,
      "nausea_reports": 10419,
      "nausea_share_of_drug_reports": 0.117953,
      "nausea_share_is_upper_bound": false,
      "dose_term_family_share_floor": 0.151904,
      "dose_term_family_share_ceiling": 0.151904,
      "dose_term_family_terms_outside_stored": 0,
      "serious_share_of_drug_reports": 0.260664,
      "twenty_fifth_stored_term_reports": 1847,
      "search_expression": "patient.drug.openfda.brand_name:\"TRULICITY\" OR patient.drug.medicinalproduct:\"TRULICITY\""
    },
    {
      "drug": "Ozempic",
      "molecule": "semaglutide",
      "application_holder": "Novo Nordisk",
      "device_class": "You pick the dose on a dial",
      "presentation": "a 3 mL pen set to one of several doses, holding four doses",
      "total_reports": 66161,
      "incorrect_dose_reports": null,
      "incorrect_dose_share_of_drug_reports": 0.022823,
      "incorrect_dose_share_is_upper_bound": true,
      "incorrect_dose_rank_among_stored_terms": null,
      "nausea_reports": 9751,
      "nausea_share_of_drug_reports": 0.147383,
      "nausea_share_is_upper_bound": false,
      "dose_term_family_share_floor": 0,
      "dose_term_family_share_ceiling": 0.091292,
      "dose_term_family_terms_outside_stored": 4,
      "serious_share_of_drug_reports": 0.490969,
      "twenty_fifth_stored_term_reports": 1510,
      "search_expression": "patient.drug.openfda.brand_name:\"OZEMPIC\" OR patient.drug.medicinalproduct:\"OZEMPIC\""
    },
    {
      "drug": "Rybelsus",
      "molecule": "semaglutide",
      "application_holder": "Novo Nordisk",
      "device_class": "You swallow a tablet",
      "presentation": "a 3 mg, 7 mg or 14 mg tablet",
      "total_reports": 7379,
      "incorrect_dose_reports": null,
      "incorrect_dose_share_of_drug_reports": 0.020599,
      "incorrect_dose_share_is_upper_bound": true,
      "incorrect_dose_rank_among_stored_terms": null,
      "nausea_reports": 1060,
      "nausea_share_of_drug_reports": 0.143651,
      "nausea_share_is_upper_bound": false,
      "dose_term_family_share_floor": 0,
      "dose_term_family_share_ceiling": 0.082396,
      "dose_term_family_terms_outside_stored": 4,
      "serious_share_of_drug_reports": 0.56051,
      "twenty_fifth_stored_term_reports": 152,
      "search_expression": "patient.drug.openfda.brand_name:\"RYBELSUS\" OR patient.drug.medicinalproduct:\"RYBELSUS\""
    },
    {
      "drug": "Wegovy",
      "molecule": "semaglutide",
      "application_holder": "Novo Nordisk",
      "device_class": "It comes ready-measured",
      "presentation": "single-dose pen or syringe, one strength each; a four-dose pen at 2.4 mg",
      "total_reports": 21044,
      "incorrect_dose_reports": null,
      "incorrect_dose_share_of_drug_reports": 0.019816,
      "incorrect_dose_share_is_upper_bound": true,
      "incorrect_dose_rank_among_stored_terms": null,
      "nausea_reports": 2861,
      "nausea_share_of_drug_reports": 0.135953,
      "nausea_share_is_upper_bound": false,
      "dose_term_family_share_floor": 0,
      "dose_term_family_share_ceiling": 0.079262,
      "dose_term_family_terms_outside_stored": 4,
      "serious_share_of_drug_reports": 0.45001,
      "twenty_fifth_stored_term_reports": 417,
      "search_expression": "patient.drug.openfda.brand_name:\"WEGOVY\" OR patient.drug.medicinalproduct:\"WEGOVY\""
    },
    {
      "drug": "Saxenda",
      "molecule": "liraglutide",
      "application_holder": "Novo Nordisk",
      "device_class": "You pick the dose on a dial",
      "presentation": "a 3 mL pen set to 0.6, 1.2, 1.8, 2.4 or 3 mg",
      "total_reports": 10040,
      "incorrect_dose_reports": null,
      "incorrect_dose_share_of_drug_reports": 0.019223,
      "incorrect_dose_share_is_upper_bound": true,
      "incorrect_dose_rank_among_stored_terms": null,
      "nausea_reports": 1369,
      "nausea_share_of_drug_reports": 0.136355,
      "nausea_share_is_upper_bound": false,
      "dose_term_family_share_floor": 0.022012,
      "dose_term_family_share_ceiling": 0.079681,
      "dose_term_family_terms_outside_stored": 3,
      "serious_share_of_drug_reports": 0.574203,
      "twenty_fifth_stored_term_reports": 193,
      "search_expression": "patient.drug.openfda.brand_name:\"SAXENDA\" OR patient.drug.medicinalproduct:\"SAXENDA\""
    },
    {
      "drug": "Victoza",
      "molecule": "liraglutide",
      "application_holder": "Novo Nordisk",
      "device_class": "You pick the dose on a dial",
      "presentation": "a pen set to 0.6, 1.2 or 1.8 mg",
      "total_reports": 44086,
      "incorrect_dose_reports": null,
      "incorrect_dose_share_of_drug_reports": 0.016649,
      "incorrect_dose_share_is_upper_bound": true,
      "incorrect_dose_rank_among_stored_terms": null,
      "nausea_reports": 6456,
      "nausea_share_of_drug_reports": 0.146441,
      "nausea_share_is_upper_bound": false,
      "dose_term_family_share_floor": 0,
      "dose_term_family_share_ceiling": 0.066597,
      "dose_term_family_terms_outside_stored": 4,
      "serious_share_of_drug_reports": 0.467359,
      "twenty_fifth_stored_term_reports": 734,
      "search_expression": "patient.drug.openfda.brand_name:\"VICTOZA\" OR patient.drug.medicinalproduct:\"VICTOZA\""
    }
  ]
}