{
  "format": "healthspanledger-research-codebook",
  "schemaVersion": 1,
  "dataset": {
    "id": "clinicaltrials-pipeline",
    "name": "Registered clinical trials by peptide and GLP-1 compound",
    "canonicalUrl": "https://healthspanledger.com/pipeline",
    "edition": "2026.08",
    "version": "198288fe6fa4"
  },
  "columns": [
    {
      "name": "compound",
      "type": "string",
      "nullable": false,
      "description": "Stable HealthspanLedger slug for the tracked compound."
    },
    {
      "name": "compound_name",
      "type": "string",
      "nullable": false,
      "description": "Reader-facing name of the tracked compound."
    },
    {
      "name": "names_searched",
      "type": "string",
      "nullable": false,
      "description": "Registered names and development codes searched, separated by semicolons."
    },
    {
      "name": "registered_interventional_studies",
      "type": "number",
      "nullable": false,
      "description": "Unique registered studies that name the compound as an intervention.",
      "unit": "studies"
    },
    {
      "name": "studies_recruiting",
      "type": "number",
      "nullable": false,
      "description": "Included studies currently open to new participants.",
      "unit": "studies"
    },
    {
      "name": "studies_active",
      "type": "number",
      "nullable": false,
      "description": "Included studies in an active registry status, whether or not recruiting.",
      "unit": "studies"
    },
    {
      "name": "observational_studies",
      "type": "number",
      "nullable": false,
      "description": "Registered observational studies found for the compound and excluded from intervention counts.",
      "unit": "studies"
    },
    {
      "name": "title_mention_only_studies",
      "type": "number",
      "nullable": false,
      "description": "Studies that mention the compound but do not name it as a registered intervention.",
      "unit": "studies"
    },
    {
      "name": "highest_phase",
      "type": "string",
      "nullable": true,
      "description": "Most advanced registered phase among included interventional studies.",
      "missingMeaning": "No included study publishes a trial phase."
    },
    {
      "name": "highest_phase_label",
      "type": "string",
      "nullable": true,
      "description": "Plain-language rendering of the most advanced registered phase.",
      "missingMeaning": "No included study publishes a trial phase."
    },
    {
      "name": "highest_active_phase",
      "type": "string",
      "nullable": true,
      "description": "Most advanced phase among included studies with an active status.",
      "missingMeaning": "No active included study publishes a phase."
    },
    {
      "name": "next_primary_completion",
      "type": "string",
      "nullable": true,
      "description": "Earliest upcoming primary-completion date among included active studies.",
      "missingMeaning": "No included active study has an upcoming primary-completion date."
    },
    {
      "name": "next_primary_completion_is_estimate",
      "type": "boolean",
      "nullable": true,
      "description": "Whether the next primary-completion date is marked estimated by the sponsor.",
      "missingMeaning": "There is no next primary-completion record to classify."
    },
    {
      "name": "next_primary_completion_nct_id",
      "type": "string",
      "nullable": true,
      "description": "ClinicalTrials.gov identifier attached to the next primary-completion date.",
      "missingMeaning": "There is no next primary-completion record."
    },
    {
      "name": "registrations_quarantined",
      "type": "number",
      "nullable": false,
      "description": "Registrations excluded after the dataset's authenticity checks.",
      "unit": "studies"
    },
    {
      "name": "searches_that_failed",
      "type": "number",
      "nullable": false,
      "description": "Configured compound-name searches that did not return a validated response.",
      "unit": "searches"
    }
  ]
}