{
  "format": "healthspanledger-research-codebook",
  "schemaVersion": 1,
  "dataset": {
    "id": "clinicaltrials-transdermal",
    "name": "Registered human trials of a peptide delivered through skin",
    "canonicalUrl": "https://healthspanledger.com/guides/glp-1-microneedle-patches",
    "edition": "2026.08",
    "version": "bcb8762b13b6"
  },
  "columns": [
    {
      "name": "molecule",
      "type": "string",
      "nullable": false,
      "description": "Stable lowercase key for the molecule searched."
    },
    {
      "name": "molecule_name",
      "type": "string",
      "nullable": false,
      "description": "Reader-facing name of the searched molecule."
    },
    {
      "name": "molecular_weight_g_per_mol",
      "type": "number",
      "nullable": false,
      "description": "Molecular weight recorded for the molecule.",
      "unit": "grams per mole"
    },
    {
      "name": "pubchem_cid",
      "type": "number",
      "nullable": false,
      "description": "PubChem compound identifier used to anchor molecular identity."
    },
    {
      "name": "is_glp1",
      "type": "boolean",
      "nullable": false,
      "description": "Whether the molecule is a GLP-1 receptor agonist in this comparison."
    },
    {
      "name": "names_searched",
      "type": "string",
      "nullable": false,
      "description": "Names and development codes searched in ClinicalTrials.gov, separated by semicolons."
    },
    {
      "name": "registered_transdermal_studies",
      "type": "number",
      "nullable": false,
      "description": "Unique human studies testing delivery through skin.",
      "unit": "studies"
    },
    {
      "name": "highest_phase",
      "type": "string",
      "nullable": true,
      "description": "Most advanced registered phase among included transdermal studies.",
      "missingMeaning": "No included study publishes a trial phase."
    },
    {
      "name": "highest_phase_label",
      "type": "string",
      "nullable": true,
      "description": "Plain-language rendering of the most advanced registered phase.",
      "missingMeaning": "No included study publishes a trial phase."
    },
    {
      "name": "any_study_recruiting",
      "type": "boolean",
      "nullable": false,
      "description": "Whether at least one included transdermal study is currently recruiting."
    },
    {
      "name": "any_results_posted",
      "type": "boolean",
      "nullable": false,
      "description": "Whether at least one included study has posted registry results."
    },
    {
      "name": "nct_ids",
      "type": "string",
      "nullable": false,
      "description": "Included ClinicalTrials.gov identifiers, separated by semicolons."
    },
    {
      "name": "searches_that_failed",
      "type": "number",
      "nullable": false,
      "description": "Configured molecule-name searches that did not return a validated response.",
      "unit": "searches"
    },
    {
      "name": "why_tracked",
      "type": "string",
      "nullable": false,
      "description": "Predeclared reason the molecule belongs in the transdermal comparison set."
    }
  ]
}