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Symptom questions

Side effects, one symptom at a time

Choose a symptom below to see which compounds list it, how often it appears and which sources do not mention it. 6 compounds have an FDA-label side-effect record, 19 have trial-only records and 11 have no published human safety record.

What matters first

Compound guides
36
FDA-label profiles
6
Trial-only profiles
19
No human safety record
11

Choose a symptom

Does tirzepatide cause constipation?

Carried on 8 of 36FDA label

The label for tirzepatide lists constipation. See how often people had it in studies of this drug and other GLP-1 medicines.

Does Mounjaro cause fatigue?

Carried on 5 of 36FDA label

The Mounjaro label lists fatigue as a side effect. See how often studies reported it and which other drugs also list it.

Does Ozempic cause muscle loss?

Carried on 1 of 36FDA label

Ozempic side-effect lists do not measure muscle loss. Learn what this safety data can answer and why studies use body scans instead.

Does a GLP-1 cause diarrhea?

Carried on 7 of 36FDA label

Drug labels list diarrhea as a common side effect. FDA reports also include it for all eight GLP-1 brands in this comparison.

Does a GLP-1 cause burping?

Not carried on any of 36

No compound guide lists burping, but FDA reports include it for two of eight brands—and both are tirzepatide. See what that split does and does not mean.

Every question against every record

The whole section in one grid. Listed means that record names the symptom itself. Grouped means it only shows up inside a combined figure — stomach problems counted together, for instance. Each symptom page gives the frequency behind every cell, with its source.

Each symptom question in this section against each of the 36 compound guides, showing whether the page names the reaction, carries it inside a grouped figure, or does not carry it.
QuestionTirzepatideSemaglutideLiraglutideRetatrutideCagrilintideSurvodutideBPC-157TesamorelinPT-141CJC-1295IpamorelinTB-500GHK-CuSermorelinMOTS-cAOD-9604NAD+EpitalonKisspeptin-10DSIPHexarelinIGF-1 LR3PEG-MGFLL-37KPVThymosin alpha-1SS-31SemaxSelankMelanotan IIMazdutidePinealonAHK-CuVK2735ZenagamtidePemvidutide
ConstipationListedListedListedListedGroupedGroupedNo recordNot carriedNot carriedNot carriedNot carriedNo recordNo recordNot carriedNo recordNot carriedNot carriedNo recordNo recordNot carriedNot carriedNo recordNo recordNot carriedNo recordNot carriedNot carriedNot carriedNo recordNot carriedNot carriedNot carriedNo recordListedNot carriedListed
NauseaListedListedListedListedListedListedNo recordNot carriedListedNot carriedNot carriedNo recordNo recordGroupedNo recordNot carriedNot carriedNo recordNo recordNot carriedNot carriedNo recordNo recordNot carriedNo recordNot carriedNot carriedNot carriedNo recordListedListedNot carriedNo recordListedNot carriedListed
FatigueListedListedNot carriedNot carriedNot carriedNot carriedNo recordNot carriedListedNot carriedNot carriedNo recordNo recordNot carriedNo recordListedNot carriedNo recordNo recordNot carriedNot carriedNo recordNo recordNot carriedNo recordNot carriedNot carriedNot carriedNo recordGroupedNot carriedNot carriedNo recordNot carriedNot carriedNot carried
Hair lossNot carriedNot carriedNot carriedNot carriedNot carriedNot carriedNo recordNot carriedNot carriedNot carriedNot carriedNo recordNo recordNot carriedNo recordNot carriedNot carriedNo recordNo recordNot carriedNot carriedNo recordNo recordNot carriedNo recordNot carriedNot carriedNot carriedNo recordNot carriedNot carriedNot carriedNo recordNot carriedNot carriedNot carried
Muscle lossNot carriedNot carriedNot carriedNot carriedNot carriedNot carriedNo recordGroupedNot carriedNot carriedNot carriedNo recordNo recordNot carriedNo recordNot carriedNot carriedNo recordNo recordNot carriedNot carriedNo recordNo recordNot carriedNo recordNot carriedNot carriedNot carriedNo recordNot carriedNot carriedNot carriedNo recordNot carriedNot carriedNot carried
DiarrheaListedListedListedListedGroupedNot carriedNo recordNot carriedNot carriedNot carriedNot carriedNo recordNo recordNot carriedNo recordNot carriedNot carriedNo recordNo recordNot carriedNot carriedNo recordNo recordNot carriedNo recordNot carriedNot carriedNot carriedNo recordNot carriedListedNot carriedNo recordNot carriedNot carriedListed
BurpingNot carriedNot carriedNot carriedNot carriedNot carriedNot carriedNo recordNot carriedNot carriedNot carriedNot carriedNo recordNo recordNot carriedNo recordNot carriedNot carriedNo recordNo recordNot carriedNot carriedNo recordNo recordNot carriedNo recordNot carriedNot carriedNot carriedNo recordNot carriedNot carriedNot carriedNo recordNot carriedNot carriedNot carried

One symptom or one compound?

Use this section when you have one symptom and want to compare every compound that lists it. Use a compound’s side-effect guide when you want its complete reaction list and warnings. For example, see the full tirzepatide side-effect guide.

2 of the 7 questions above have no answer in the available sources. We leave those gaps visible. See how we judge the evidence in how we source each answer.

More side-effect questions

Want the complete reaction list for one medicine? Start with the FDA-label guides for semaglutide and tirzepatide. Browse the full compound index for all 36 compounds, or use the side-by-side comparisons to compare two.

Trial side-effect tables and reports filed after a drug reaches the market answer different questions. See the reports in what people actually reported.

Need to know how long a symptom may last? No label or trial states a set duration for every person.

Checking a combination? See what not to mix. Missing interaction data does not prove a combination is safe.

Wondering what happens after treatment stops? Three trials measured weight regain after semaglutide or tirzepatide ended.

Every figure on a symptom page is read off one of these sources at render time, and carries that record’s own citation.

The GLP-1 suicide-warning timeline

Why the regulator moved from an open question to a warning-removal request.

What three alcohol trials actually measured

Three randomized semaglutide trials, with the primary and null outcomes kept together.

Tirzepatide and birth control pills

The current four-week instruction after starting and after every dose increase.

Every reconstitution calculator on this site, in one place

The generic tool plus the 36 compound-specific versions built on it.

Why nobody can say how long it lasts

No source cited on this site states how long any of these reactions lasts, and that is the answer.

Where the evidence on stopping runs out

Whether stepping down first helps, and what happens on restarting, are named here as unstudied rather than answered.

Every interaction these pages carry

Nothing on it is built by inference: no mechanism, no “probably avoid”, no list assembled from how a drug works.

Burping across all 36 compound guides

None of the sources reviewed lists burping — and that missing answer is shown clearly.