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Reconstitution · Retatrutide

Retatrutide dosage calculator

Pick the vial, the water you added and the dose. Get the exact draw in units for the syringe in your hand.

Step 1 of 4

  1. How many mg are in your vial?
    Vial amounttotal mg in the calculation
  2. How many mL of water did you add?
  3. What dose do you want to convert?
  4. Which syringe are you using?
Draw to
20.0units

0.20 mL in the syringe · 10 calculated doses from this amount

20.0 units on a U-100 insulin syringe · 1 mL · lines every 2 units, which is 0.20 milliliters. The draw lands on a syringe line.

Easy to read on this syringe. The calculated volume matches the 20-unit line. No rounding is needed.

20 mg ÷ 2 mL = 10.00 mg/mL
→ 100 mcg/unit · 2 mg = 0.200 mL = 20.0 units

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Show the math and syringe details

Can this syringe show the result clearly?

Easy to read on this syringe. 20.0 u is exactly the 20-unit line on a U-100 — no rounding error at all.

Want an easier syringe number?

This setup is already easy to read. Changing the water between 0.5 and 3 mL would not put 2 mg closer to a line on this U-100 syringe.

Adding more water makes the mixture less concentrated, so the same dose uses more syringe units. It does not change how much peptide is in the vial.

This setup is in the address bar — every input is part of the link.

Educational math, not medical advice — dosing decisions belong to a licensed clinician. The available tabs also show supply calculations and any sourced schedule.

How to use the calculator

  1. 1

    Enter the amount in the vial

    Use the total mg printed on your Retatrutide vial.

  2. 2

    Enter the water you added

    Use the amount of water added to that vial, in mL.

  3. 3

    Enter the dose you want to convert

    Choose mg or mcg, then match the result to your syringe.

Retatrutide is an experimental weekly injection being tested for weight loss. It acts on three hormone signals linked to appetite and metabolism. People buy unapproved versions under the nickname Reta in hopes of losing weight.

A published phase 2 trial found large average weight loss. Phase 3 trials are underway, but FDA has not approved retatrutide.

Examples using 20 mg of Retatrutide

Each row uses 20 mg and the liquid volume shown. Dividing the amount by that volume gives the calculated concentration. The rows are arithmetic examples, not alternative product preparations.

◆ How liquid volume changes the resultdose used: 2 mg

With 1 mL bacteriostatic water

10.0 units

Concentration
20.00 mg/mL
Each U-100 unit
200.0 mcg
Syringe volume
0.100 mL
Nearest line
Exactly 10 units

With 2 mL bacteriostatic water

20.0 units

Starting example
Concentration
10.00 mg/mL
Each U-100 unit
100.0 mcg
Syringe volume
0.200 mL
Nearest line
Exactly 20 units

The amount, liquid volume and dose shown here are the calculator’s starting example for Retatrutide. Replace them with your own values. Every result in the table is calculated from those inputs.

Drawn from once a week at 2 mg, a 20 mg vial yields 10 doses — about 10.0 weeks of supply. No storage limit is assigned to this example. Follow the dispensing label for the specific product.

Retatrutide: a syringe reading depends on the whole calculation

A retatrutide amount in milligrams can correspond to different syringe readings. The vial strength and water volume determine the concentration. A unit count without those details does not tell you how much retatrutide it represents.

Open the mixing details3 notes

The presets are examples, not mixing instructions

This calculator includes several vial strengths and water volumes. Choosing a preset fills in the arithmetic; it does not establish how a particular preparation should be mixed. The tool cannot check the contents of a vial or supply instructions that are missing from it.

The study amounts shown on the page have their own research context. They do not turn the available presets into an approved product or a personal dosing schedule.

A change in concentration changes the reading

For the same amount of retatrutide, a more concentrated solution requires a smaller volume. A less concentrated solution requires a larger volume. That is why changing either the vial strength or the water can move the result along the syringe scale even when the entered dose stays the same.

The worked table shows these differences together. A small calculated volume may fall between syringe lines; a larger one may approach the syringe’s capacity. The measurement details explain those limits.

A copied unit count leaves out essential information

A syringe unit measures volume, not the mass of retatrutide. A saved reading from another calculation is only comparable when the dose, concentration and syringe type match.

The milligram amount and the syringe reading describe different parts of the same result. Keeping them together with the vial and water inputs lets you see why the answer changed, rather than treating the unit count as a dose on its own.

Retatrutide trial starting doses and target doses differ

In the published weight-loss trial, some groups began at a lower amount before reaching their assigned weekly dose. The dose entered in a calculator cannot describe that full course of treatment.

Read the supporting evidence3 supporting notes

Read the starting amount beside the target

The study compared groups with different target doses and starting amounts. Its results belong to those trial schedules, including the time spent increasing the dose. A single figure copied from the results table leaves that context out.

A trial result is not an individual forecast

Weight change was measured in trial participants over many months. The calculator only works out liquid volume from the values entered. It cannot predict weight change, side effects or whether a trial schedule suits a person.

The study does not identify an unrelated vial

A published retatrutide dose does not verify the strength, contents or storage life of a vial obtained outside that study. Those questions remain separate from the arithmetic shown here.

Units to dose at 10.00 mg/mL

Mix 20 mg into 2 mL and one U-100 unit carries 100.0 mcg. The table shows how much peptide is in each numbered syringe line. These are conversion examples, not suggested doses.

Open the unit conversion table10 rows
Numbered U-100 syringe lines converted to volume and mass at 10.00 milligrams per milliliter.
U-100 lineVolumeMass (mcg)Mass (mg)
10 u0.10 mL1,000 mcg1 mg
20 u0.20 mL2,000 mcg2 mg
30 u0.30 mL3,000 mcg3 mg
40 u0.40 mL4,000 mcg4 mg
50 u0.50 mL5,000 mcg5 mg
60 u0.60 mL6,000 mcg6 mg
70 u0.70 mL7,000 mcg7 mg
80 u0.80 mL8,000 mcg8 mg
90 u0.90 mL9,000 mcg9 mg
100 u1.00 mL10,000 mcg10 mg

How the math works

  1. Concentration — divide the amount entered by the liquid volume used in the calculation: mg ÷ mL = mg/mL. This tells you how many mg are in each mL.
  2. Volume — the dose divided by that concentration: dose ÷ (mg/mL) = mL.
  3. Units — on a U-100 syringe one unit is 0.01 mL, so mL × 100 = units. A U-40 unit is 0.025 mL, so the wrong barrel is a 2.5× error. That is why the calculator asks which one you have.
  4. Rounding gap — the exact draw against the nearest syringe line: |exact − nearest line| ÷ exact × 100 = % difference.

Medically reviewed by Kenneth Montecillo, MD2026-09-07open the primary sources

Useful guides for this calculation

The math is only one part of the question. These guides cover the compound, published doses, side effects, mixing steps and supplies.

Questions readers ask

How many units is 1mg of reta?

Between 3.3 and 20 units across the six preset combinations. A 20 mg vial in 1 mL puts 1 mg at 5 units. A 10 mg vial in 2 mL puts the same 1 mg at 20 units.

That is a sixfold spread on one number. It is why a unit count copied from elsewhere is unusable without the vial size and water volume that produced it. Only the milligrams are the dose.

How to reconstitute a 10mg vial of retatrutide?

Adding 1 mL gives 10 mg/mL, while 2 mL gives 5 mg/mL. One U-100 unit then holds 100 or 50 micrograms.

10 mg is the smallest of three sizes here, and it reads most comfortably at the low end of the studied span. The phase 2 arms ran 1, 4, 8 and 12 mg once weekly. At 5 mg/mL, 12 mg would be 240 units — well past a single barrel.

How to figure out peptide dosing?

The arithmetic and the choosing are separate jobs, and only the first has an answer here. Concentration is vial strength divided by water added. One U-100 unit is 0.01 mL, so units are dose divided by concentration, times 100.

Which quantity goes into that formula is not something a calculator settles. Retatrutide has no approved label in any country, so the only published quantities are the phase 2 arms. Those are study data from 338 participants, not a schedule.

How much BAC water for 10 mg retatrutide calculator?

Either listed volume, because on a 10 mg vial the water leaves the supply alone. At 2 mg a draw the vial holds five doses whichever you pick.

What moves is the reading: 20 units at 1 mL, 40 units at 2 mL, one identical injection. The wider reading is easier to hit and puts twice the liquid under the skin. Neither is more correct than the other.

1primary source, each with the day we read it — open the documents used on this page