Peptide and GLP-1 dosage
Peptide dosage charts and schedules
Choose a compound to see where its dose comes from. Of the 36 compounds covered, 2 have one approved schedule and 1 have schedules that change by product. Another 6 have doses tested in human trials. The remaining 27 have no approved or trial-based schedule.
Source: Based on 36 compound guides and 8 FDA brand labels
What matters first
Which compounds have a dose schedule at all?
One row per record. The middle column is the whole point: it says what the numbers rest on, and a dash means nobody has published any.
| Compound | Numbers come from | Steps, arms or products | Range covered | Grade |
|---|---|---|---|---|
| Semaglutide | Approved label | 5 | 0.25–2.4 mg | FDA label |
| Tirzepatide | Approved label | 6 | 2.5–15 mg | FDA label |
| Liraglutide | Product labels | 2 | Victoza ≤1.8 mg · Saxenda ≤3 mg | FDA label |
| Cagrilintide | Trial arms | 5 | 0.3–4.5 mg | Human trial |
| Mazdutide | Trial arms | 2 | 4–6 mg | Human trial |
| Pemvidutide | Trial arms | 3 | 1.2–2.4 mg | Human trial |
| Retatrutide | Trial arms | 4 | 1–12 mg | Human trial |
| Survodutide | Trial arms | 4 | 0.6–4.8 mg | Human trial |
| VK2735 | Trial arms | 4 | 2.5–15 mg | Human trial |
| AHK-Cu | Nothing published | — | — | no human dose shown to work |
| AOD-9604 | Nothing published | — | — | limited human data |
| BPC-157 | Nothing published | — | — | no human dose shown to work |
| CJC-1295 | Nothing published | — | — | limited human data |
| DSIP | Nothing published | — | — | limited human data |
| Epitalon | Nothing published | — | — | limited human data |
| GHK-Cu | Nothing published | — | — | indirect evidence |
| Hexarelin | Nothing published | — | — | limited human data |
| IGF-1 LR3 | Nothing published | — | — | no human dose shown to work |
| Ipamorelin | Nothing published | — | — | Human trial |
| Kisspeptin-10 | Nothing published | — | — | limited human data |
| KPV | Nothing published | — | — | no human dose shown to work |
| LL-37 | Nothing published | — | — | limited human data |
| Melanotan II | Nothing published | — | — | limited human data |
| MOTS-c | Nothing published | — | — | no human dose shown to work |
| NAD+ | Nothing published | — | — | limited human data |
| PEG-MGF | Nothing published | — | — | no human dose shown to work |
| Pinealon | Nothing published | — | — | limited human data |
| PT-141 | Nothing published | — | — | FDA label |
| Selank | Nothing published | — | — | limited human data |
| Semax | Nothing published | — | — | limited human data |
| Sermorelin | Nothing published | — | — | limited human data |
| SS-31 | Nothing published | — | — | FDA label |
| TB-500 | Nothing published | — | — | indirect evidence |
| Tesamorelin | Nothing published | — | — | FDA label |
| Thymosin alpha-1 | Nothing published | — | — | limited human data |
| Zenagamtide | Nothing published | — | — | Human trial |
Steps are titration rows on a label. Arms are dose groups in a trial. A product count means the molecule has multiple labeled schedules that remain separate on its page. They share a column because all three are the source objects a page has to work from—not because they mean the same thing.
Does a brand stop where its own drug’s chart stops?
Not always. 3 of these 8 products stop somewhere other than the molecule chart they sit on top of. A ceiling belongs to a label, and each label sets its own.
| Brand | Drug inside | Starts at | Stops at | Molecule chart stops at |
|---|---|---|---|---|
| Wegovy | Semaglutide | 0.25 mg | 7.2 mg | 2.4 mg |
| Ozempic | Semaglutide | 0.25 mg | 2 mg | 2.4 mg |
| Zepbound | Tirzepatide | 2.5 mg | 15 mg | 15 mg |
| Mounjaro | Tirzepatide | 2.5 mg | 15 mg | 15 mg |
| Trulicity | Dulaglutide | 0.75 mg | 4.5 mg | — |
| Victoza | Liraglutide | 0.6 mg | 1.8 mg | — |
| Saxenda | Liraglutide | 0.6 mg | 3 mg | — |
| Rybelsus | Semaglutide | 3 mg | 14 mg | 2.4 mg |
The last column is the top step on the molecule’s own chart, which is read from one label. A highlighted figure marks a product whose ceiling differs from it.
Two of these brands carry semaglutide and two carry tirzepatide. The rest of what separates the four labels — who they cover, what they treat, how a missed week is handled — sits with the brand pages.
One semaglutide schedule is missing from that table, and it is missing because it does not fit the columns. The tablet ladders run in 30-day blocks rather than weeks, across three products whose strengths do not convert into each other.
A second molecule now comes as a tablet too, and its schedule is a different shape again: six strengths climbing to a maximum the label never calls a settled dose. The orforglipron chart carries it, with the 9 mg cap that other medicines put on the top of it.
What is a dosage chart, really?
It is the end of a regulatory process. A sponsor runs trials, an agency reviews them, and the schedule that survives is printed on a label the manufacturer is then bound to.
That is why a chart cannot be written for a compound that has not been through it. There is no document to quote from. Sites that publish one anyway have built it backwards: they take a dose from a trial and invent a ramp that arrives there. The result looks exactly like a sourced schedule.
Trial arms are a different object again. An arm exists to map a range, so the lowest one is usually placed where the effect is expected to be small and the highest one where it starts to be hard to tolerate. Neither is a target. Reading the top arm as a goal is the most common mistake made with the 6 records in the middle group above.
The 27 records at the bottom have no label or trial schedule, and their pages say so. For 8 of them that is not the end of it: a range is circulating, so the range is shown it with the source that documents it and what the evidence does not show. The remaining 19 stop at the absence, because nothing is published to report.
How does a dose in milligrams become units on a syringe?
By division, twice. The chart gives a mass in milligrams. The syringe is marked in units, and what a unit holds depends on how the vial was mixed.
Worked once: 10 mg mixed with 2 mL of water is 5.00 mg/mL. A 2.5 mg dose is then 0.50 mL, which on a U-100 barrel reads as 50 units. Change the water and every unit figure changes while the dose does not.
Branded pens skip all of this, because the dose is set in the device. The calculator does the same arithmetic for any vial, and prints each step so it can be checked by hand.
Questions about dose schedules
Why do some compounds here have a chart and others do not?
Is a trial dose a dose anyone can follow?
Why is the same drug listed at two different top doses?
Does mixing a vial differently change the dose?
What does the source label in the last column mean?
Read a schedule in full
Each page shows the source behind its schedule. When one drug has two product labels, their schedules stay separate.
A GLP-1 tablet with no injection behind it
Peptide and bacteriostatic-water calculator for any vial
Every tablet strength on one label
What the Victoza label sets as a starting dose
How MOTS-c differs from the rest of its class
The Trulicity steps, week by week
What returns besides the weight
The Zepbound ladder as its own label prints it
- Zepbound (tirzepatide) — FDA-approved Prescribing Informationretrieved 2026-07-22FDA label
- Wegovy (semaglutide) — FDA-approved Prescribing Information (DailyMed)retrieved 2026-08-20FDA label
- Jastreboff AM et al. Triple-Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial. N Engl J Med 2023;389:514-26 (PMID 37366315)retrieved 2026-08-12Human trial
- Lau DCW et al. Once-weekly cagrilintide for weight management: dose-finding phase 2 trial. Lancet 2021;398:2160-72 (PMID 34798060)retrieved 2026-08-17Human trial
- le Roux CW et al. Glucagon and GLP-1 receptor dual agonist survodutide for obesity: dose-finding phase 2 trial. Lancet Diabetes Endocrinol 2024 (PMID 38330987)retrieved 2026-08-20Human trial
- Mateescu DM, Gavrilescu DM, Constantinescu FE, Oancea C, Ilie AC, Folescu R, Popa MD, Iurciuc S, Muresan CO, Enache A. BPC-157 as an Investigational Peptide Therapeutic: Biopharmaceutical Challenges, Formulation Strategies, and Translational Development Barriers. Pharmaceutics 2026;18(5):625 — states the quantity used off-label and that it was extrapolated informally from rodent data, with no human pharmacokinetic or safety anchorretrieved 2026-08-13indirect evidence
- Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab 2006;91(3):799-805retrieved 2026-08-12Human trial
- Ionescu M, Frohman LA. Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. J Clin Endocrinol Metab 2006;91(12):4792-7retrieved 2026-08-12Human trial
- Dominikowski A, Rękoś Z, Olejarz M, Szczepanek-Parulska E, Domin R, Ruchała M. The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration. Front Endocrinol 2026 — tabulates self-reported online dosing patterns beside the clinical doses, stating the reported values must not be read as clinically validated, regulatory-approved or saferetrieved 2026-08-12indirect evidence
- NCT01280344 — Phase II double-blind placebo-controlled dose-finding study of ipamorelin for recovery of gastrointestinal function after small or large bowel resection (Helsinn Therapeutics; 320 patients; arms 0.03 mg/kg BID, 0.06 mg/kg BID, 0.06 mg/kg TID, all intravenous)retrieved 2026-08-12Human trial
- Beck DE, Sweeney WB, McCarter MD; Ipamorelin 201 Study Group. Prospective, randomized, controlled, proof-of-concept study of the ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients. Int J Colorectal Dis 2014;29(12):1527-34retrieved 2026-08-12Human trial
- Thorner M, et al. Once daily subcutaneous growth hormone-releasing hormone therapy accelerates growth in growth hormone-deficient children during the first year of therapy (Geref International Study Group). J Clin Endocrinol Metab 1996;81(3):1189-96retrieved 2026-08-12Human trial
- Corpas E, Harman SM, Piñeyro MA, Roberson R, Blackman MR. Growth hormone (GH)-releasing hormone-(1-29) twice daily reverses the decreased GH and insulin-like growth factor-I levels in old men. J Clin Endocrinol Metab 1992;75(2):530-5retrieved 2026-08-12Human trial
- NCT00324064 — Sexually Dimorphic Effects of GHRH in Adult Growth Hormone Testing (protocol: GHRH [Geref] 1 mcg/kg intravenous push, followed by arginine)retrieved 2026-08-12Human trial
- Valentino MA, Lin JE, Waldman SA. Central and peripheral molecular targets for antiobesity pharmacotherapy. Clin Pharmacol Ther 2010;87(6):652-62 — reports the AOD-9604 12-week trial arms (1 mg/day and 10 mg/day) and the 536-subject 24-week trial that ended developmentretrieved 2026-08-12limited human data
- Rahim A, O’Neill PA, Shalet SM. Growth hormone status during long-term hexarelin therapy. J Clin Endocrinol Metab 1998;83(5):1644-9retrieved 2026-08-12Human trial
- Maccario M, Veldhuis JD, Broglio F, Di Vito L, Arvat E, Deghenghi R, Ghigo E. Impact of two or three daily subcutaneous injections of hexarelin, a synthetic growth hormone (GH) secretagogue, on 24-h GH, prolactin, adrenocorticotropin and cortisol secretion in humans. Eur J Endocrinol 2002;146(3):310-8retrieved 2026-08-12Human trial
- Massoud AF, Hindmarsh PC, Brook CG. Hexarelin-induced growth hormone, cortisol, and prolactin release: a dose-response study. J Clin Endocrinol Metab 1996;81(12):4338-41retrieved 2026-08-12Human trial
- Ji L et al. Once-Weekly Mazdutide in Chinese Adults with Obesity or Overweight. N Engl J Med 2025;392:2215-2225 (GLORY-1, NCT05607680, PMID 40421736)retrieved 2026-08-17Human trial
- Gao L et al. Treatment With 9-mg Mazdutide for Weight Reduction in Chinese Adults With Obesity: The GLORY-2 Randomized Clinical Trial. JAMA 2026;336(5):377-388 — 60 weeks, ClinicalTrials.gov NCT06164873 (PMID 42251595)retrieved 2026-08-17Human trial
- Zhu D, Zhao J et al. Mazdutide versus placebo in Chinese adults with type 2 diabetes. Nature 2026;652:174-180 — a 24-week phase 3 trial of 4 mg and 6 mg weekly, followed by 24 weeks of open treatment (PMID 41407859)retrieved 2026-08-17Human trial
- Ji L, Jiang H et al. A phase 2 randomized controlled trial of mazdutide in Chinese overweight adults or adults with obesity. Nat Commun 2023;14:8289 — 248 participants across 3 mg, 4.5 mg and 6 mg arms over 24 weeks, ClinicalTrials.gov NCT04904913 (PMID 38092790)retrieved 2026-08-17Human trial
- Ji L, Gao L et al. Safety and efficacy of a GLP-1 and glucagon receptor dual agonist mazdutide (IBI362) 9 mg and 10 mg in Chinese adults with overweight or obesity: a randomised, placebo-controlled, multiple-ascending-dose phase 1b trial. EClinicalMedicine 2022;54:101691 (PMID 36247927)retrieved 2026-08-17Human trial
- Bays HE et al. Weekly Subcutaneous VK2735 for Weight Management: Phase 2 VENTURE Study. Obesity 2026;34:537-549 (NCT06068946, PMID 41508550)retrieved 2026-08-16Human trial
- Altimmune 2024 Form 10-K — 48-week MOMENTUM phase 2 obesity resultsretrieved 2026-08-17Sponsor results filed with the SEC
- Harrison SA et al. Pemvidutide in MASLD: randomized, double-blind trial (NCT05006885, PMID 39002641)retrieved 2026-08-17Human trial
- Noureddin M et al. Pemvidutide in MASH: 24-week IMPACT phase 2b results (NCT05989711, PMID 41237796)retrieved 2026-08-17Human trial
- NCT06987513 — RECLAIM phase 2 pemvidutide trial in alcohol use disorderretrieved 2026-08-17Human trial
- NCT07009860 — RESTORE phase 2 pemvidutide trial in alcohol-associated liver diseaseretrieved 2026-08-17Human trial
- Altimmune SEC exhibit — PERFORMA phase 3 MASH program initiated in August 2026retrieved 2026-08-17Company program update filed with the SEC
- Wegovy (semaglutide) Prescribing Information, revised 06/2026 — Drugs@FDA NDA 215256/S-025retrieved 2026-08-12FDA label
- Ozempic (semaglutide) injection — FDA-approved Prescribing Information (DailyMed)retrieved 2026-08-12FDA label
- Drugs@FDA approval history — NDA 209637, Ozempic (semaglutide) injectionretrieved 2026-08-12FDA label
- Zepbound (tirzepatide) injection — FDA-approved Prescribing Information (DailyMed)retrieved 2026-08-12FDA label
- Zepbound (tirzepatide) Prescribing Information, revised 02/2026 — Drugs@FDA NDA 217806/S-042retrieved 2026-08-12FDA label
- Mounjaro (tirzepatide) injection — FDA-approved Prescribing Information (DailyMed)retrieved 2026-08-12FDA label
- Drugs@FDA approval history — NDA 215866, Mounjaro (tirzepatide) injectionretrieved 2026-08-12FDA label
- Trulicity (dulaglutide) injection — FDA-approved Prescribing Information (DailyMed)retrieved 2026-08-13FDA label
- Trulicity (dulaglutide) Prescribing Information, revised 03/2026 — Drugs@FDA BLA 125469/S-065retrieved 2026-08-13FDA label
- Victoza (liraglutide) injection — FDA-approved Prescribing Information (DailyMed)retrieved 2026-08-13FDA label
- Victoza (liraglutide) Prescribing Information, revised 10/2025 — Drugs@FDA NDA 022341/S-046retrieved 2026-08-13FDA label
- Saxenda (liraglutide) injection — FDA-approved Prescribing Information (DailyMed)retrieved 2026-08-13FDA label
- Saxenda (liraglutide) Prescribing Information, revised 02/2026 — Drugs@FDA NDA 206321/S-025retrieved 2026-08-13FDA label
- Rybelsus and Ozempic (semaglutide) tablets — one FDA-approved Prescribing Information covering both names (DailyMed)retrieved 2026-08-20FDA label
- Rybelsus (semaglutide) tablets Prescribing Information, revised 01/2026 — Drugs@FDA NDA 213051/S-030retrieved 2026-08-13FDA label