Peptide dosage charts and schedules
Choose a compound to see where its dose comes from. Find approved schedules, doses studied in trials and reported ranges, with their limits explained. For a prescribed brand, use its own product guide.
Find a compound dosage guide
FDA label schedules
Published steps from an approved product label.
Schedules that depend on the product
The same ingredient can have different doses for different products or uses.
Doses studied in human trials
Amounts tested in study groups. These are not approved treatment schedules.
Reported ranges
Amounts described in the sources, with the limits of those reports stated in each guide.
No established dose
Read what is known and which dose information is missing.
Find your brand’s dosage guide
The ingredient alone does not tell you the dose. Brand labels set different starting doses, limits and timing. Open the full guide for the steps, approved uses and age limits.
| Product | Starting dose | Label maximum |
|---|---|---|
Semaglutide · Once weekly Subcutaneous injection in the abdomen, thigh or upper arm | 0.25 mg | 7.2 mg Only weight reduction in adults can reach 7.2 mg. The label asks for at least 4 weeks at 2.4 mg first, and for a clinical reason to go further. The FDA added this dose on 2026-03-19. |
Semaglutide · Once weekly Subcutaneous injection in the abdomen, thigh or upper arm | 0.25 mg | 2 mg 2 mg once weekly is the maximum recommended dosage. It was not on the original label: the FDA added it as a third maintenance dose on 2022-03-28. |
Tirzepatide · Once weekly Subcutaneous injection in the abdomen, thigh or upper arm | 2.5 mg | 15 mg 15 mg once weekly is the maximum for every approved use of Zepbound. The label sets no higher dose. |
Tirzepatide · Once weekly Subcutaneous injection in the abdomen, thigh or upper arm | 2.5 mg | 15 mg 15 mg once weekly is the maximum for adults. For pediatric patients aged 10 years and older, the maximum is 10 mg once weekly. |
Dulaglutide · Once weekly Subcutaneous injection in the abdomen, thigh or upper arm | 0.75 mg | 4.5 mg 4.5 mg once weekly is the maximum for adults. For pediatric patients aged 10 years and older, the maximum is 1.5 mg once weekly. |
Liraglutide · Once daily Subcutaneous injection in the abdomen, thigh or upper arm | 0.6 mg | 1.8 mg 1.8 mg once daily is the maximum for adults and pediatric patients aged 10 years and older. |
Liraglutide · Once daily Subcutaneous injection in the abdomen, thigh or upper arm | 0.6 mg | 3 mg For adults, 3 mg once daily is the recommended dose; the label says to stop if it cannot be tolerated. Pediatric patients aged 12 years and older may use 2.4 mg daily if they cannot tolerate 3 mg. The label says to stop if they cannot tolerate 2.4 mg. |
Orforglipron · Once daily Tablet, swallowed whole | 0.8 mg | 17.2 mg 17.2 mg once daily is the label maximum. When a strong CYP3A4 inhibitor is used at the same time, the label sets a lower maximum of 9 mg once daily. |
Rybelsus Semaglutide · Once daily Tablet, swallowed whole | 3 mg | 14 mg 14 mg once daily is the maximum. One label now covers both Rybelsus and the Ozempic tablet, and it says in its own words that the two are not swappable milligram for milligram. 7 mg of one matches 4 mg of the other, and 14 mg matches 9 mg. |
Tablet dosage guides
Tablets have their own strengths and schedules. A tablet dose does not convert directly to an injection dose.
- Wegovy pills and other semaglutide tablets
Compare the separate product schedules and instructions for taking each tablet.
- Foundayo (orforglipron)
See the starting dose, later steps and limits when taken with other medicines.
What each kind of dose guide tells you
- Approved schedule
- Steps and timing from a product label. The guide keeps the stated use, age group and limits with those steps.
- Trial doses
- Amounts given to study groups under a research protocol. A study group’s dose is not a target for someone outside the trial.
- Reported range
- Amounts described in a source without an approved schedule. A report of use does not show that a dose is safe or works.
- No established dose
- The available sources do not establish a dose. That does not mean nobody has used or studied the compound.
How does a dose in milligrams become units on a syringe?
The unit count depends on the dose, the liquid’s strength and the syringe type. Milligrams measure the drug amount; syringe units measure a volume.
For example, a vial with 10 mg in a total of 2 mL has a strength of 5.00 mg/mL. A 2.5 mg dose takes 0.50 mL, or 50 units on a U-100 syringe. This is an arithmetic example, not a recommended dose.
Use the total drug amount and liquid volume on your vial’s label or pharmacy instructions. For a pen, follow its own dose settings. Open the peptide calculator to see the vial conversion and each step of the math.
Questions about dose schedules
Why do some compounds have a chart and others do not?
Why do some compounds have a chart and others do not?
An approved schedule needs a product label that sets out the steps. Other guides may show trial doses or reported ranges. If the sources do not establish a dose, the guide states that gap.
Is a trial dose a dose anyone can follow?
Is a trial dose a dose anyone can follow?
No. A trial tests amounts in selected people under monitoring. Its results do not make those amounts a treatment plan for someone else. A clinician decides whether a treatment suits you.
Why can the same drug have different maximum doses?
Why can the same drug have different maximum doses?
Each product label sets the dose for its uses and age groups. The form matters too: daily tablets and weekly injections have different schedules. Use the guide for your product.
Why can the same dose need a different number of units?
Why can the same dose need a different number of units?
A less concentrated liquid needs a larger volume to hold the same amount of drug. Syringe type also changes the unit count. Use the vial’s actual strength; do not change the mix based on a chart.
What do the evidence labels mean?
What do the evidence labels mean?
They describe the source behind the compound guide. An approved label, a human trial and a report of use support different kinds of claims. Read how we assess sources.
Read a schedule in full
Each page shows the source behind its schedule. When one drug has two product labels, their schedules stay separate.
Reconstitution math for any peptide, not just this one
Every tablet strength on one label
The Victoza steps, day by day
MOTS-c without an approved label: what exists instead
The newest swallowed GLP-1 schedule
The Trulicity steps, week by week
What returns besides the weight
How long each tirzepatide step is held before the next
- Zepbound (tirzepatide) — FDA-approved Prescribing Informationretrieved 2026-09-19FDA label
- Wegovy (semaglutide) — FDA-approved Prescribing Information (DailyMed)retrieved 2026-08-20FDA label
- Jastreboff AM et al. Triple-Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial. N Engl J Med 2023;389:514-26 (PMID 37366315)retrieved 2026-08-12Human trial
- Lau DCW et al. Once-weekly cagrilintide for weight management: dose-finding phase 2 trial. Lancet 2021;398:2160-72 (PMID 34798060)retrieved 2026-08-17Human trial
- le Roux CW et al. Glucagon and GLP-1 receptor dual agonist survodutide for obesity: dose-finding phase 2 trial. Lancet Diabetes Endocrinol 2024 (PMID 38330987)retrieved 2026-08-20Human trial
- Mateescu DM, Gavrilescu DM, Constantinescu FE, Oancea C, Ilie AC, Folescu R, Popa MD, Iurciuc S, Muresan CO, Enache A. BPC-157 as an Investigational Peptide Therapeutic: Biopharmaceutical Challenges, Formulation Strategies, and Translational Development Barriers. Pharmaceutics 2026;18(5):625 — states the quantity used off-label and that it was extrapolated informally from rodent data, with no human pharmacokinetic or safety anchorretrieved 2026-08-13indirect evidence
- Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab 2006;91(3):799-805retrieved 2026-08-12Human trial
- Ionescu M, Frohman LA. Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. J Clin Endocrinol Metab 2006;91(12):4792-7retrieved 2026-08-12Human trial
- Dominikowski A, Rękoś Z, Olejarz M, Szczepanek-Parulska E, Domin R, Ruchała M. The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration. Front Endocrinol 2026 — tabulates self-reported online dosing patterns beside the clinical doses, stating the reported values must not be read as clinically validated, regulatory-approved or saferetrieved 2026-08-12indirect evidence
- NCT01280344 — Phase II double-blind placebo-controlled dose-finding study of ipamorelin for recovery of gastrointestinal function after small or large bowel resection (Helsinn Therapeutics; 320 patients; arms 0.03 mg/kg BID, 0.06 mg/kg BID, 0.06 mg/kg TID, all intravenous)retrieved 2026-08-12Human trial
- Beck DE, Sweeney WB, McCarter MD; Ipamorelin 201 Study Group. Prospective, randomized, controlled, proof-of-concept study of the ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients. Int J Colorectal Dis 2014;29(12):1527-34retrieved 2026-08-12Human trial
- Thorner M, et al. Once daily subcutaneous growth hormone-releasing hormone therapy accelerates growth in growth hormone-deficient children during the first year of therapy (Geref International Study Group). J Clin Endocrinol Metab 1996;81(3):1189-96retrieved 2026-08-12Human trial
- Corpas E, Harman SM, Piñeyro MA, Roberson R, Blackman MR. Growth hormone (GH)-releasing hormone-(1-29) twice daily reverses the decreased GH and insulin-like growth factor-I levels in old men. J Clin Endocrinol Metab 1992;75(2):530-5retrieved 2026-08-12Human trial
- NCT00324064 — Sexually Dimorphic Effects of GHRH in Adult Growth Hormone Testing (protocol: GHRH [Geref] 1 mcg/kg intravenous push, followed by arginine)retrieved 2026-08-12Human trial
- Valentino MA, Lin JE, Waldman SA. Central and peripheral molecular targets for antiobesity pharmacotherapy. Clin Pharmacol Ther 2010;87(6):652-62 — reports the AOD-9604 12-week trial arms (1 mg/day and 10 mg/day) and the 536-subject 24-week trial that ended developmentretrieved 2026-08-12limited human data
- Rahim A, O’Neill PA, Shalet SM. Growth hormone status during long-term hexarelin therapy. J Clin Endocrinol Metab 1998;83(5):1644-9retrieved 2026-08-12Human trial
- Maccario M, Veldhuis JD, Broglio F, Di Vito L, Arvat E, Deghenghi R, Ghigo E. Impact of two or three daily subcutaneous injections of hexarelin, a synthetic growth hormone (GH) secretagogue, on 24-h GH, prolactin, adrenocorticotropin and cortisol secretion in humans. Eur J Endocrinol 2002;146(3):310-8retrieved 2026-08-12Human trial
- Massoud AF, Hindmarsh PC, Brook CG. Hexarelin-induced growth hormone, cortisol, and prolactin release: a dose-response study. J Clin Endocrinol Metab 1996;81(12):4338-41retrieved 2026-08-12Human trial
- Ji L et al. Once-Weekly Mazdutide in Chinese Adults with Obesity or Overweight. N Engl J Med 2025;392:2215-2225 (GLORY-1, NCT05607680, PMID 40421736)retrieved 2026-08-17Human trial
- Gao L et al. Treatment With 9-mg Mazdutide for Weight Reduction in Chinese Adults With Obesity: The GLORY-2 Randomized Clinical Trial. JAMA 2026;336(5):377-388 — 60 weeks, ClinicalTrials.gov NCT06164873 (PMID 42251595)retrieved 2026-08-17Human trial
- Zhu D, Zhao J et al. Mazdutide versus placebo in Chinese adults with type 2 diabetes. Nature 2026;652:174-180 — a 24-week phase 3 trial of 4 mg and 6 mg weekly, followed by 24 weeks of open treatment (PMID 41407859)retrieved 2026-08-17Human trial
- Ji L, Jiang H et al. A phase 2 randomized controlled trial of mazdutide in Chinese overweight adults or adults with obesity. Nat Commun 2023;14:8289 — 248 participants across 3 mg, 4.5 mg and 6 mg arms over 24 weeks, ClinicalTrials.gov NCT04904913 (PMID 38092790)retrieved 2026-08-17Human trial
- Ji L, Gao L et al. Safety and efficacy of a GLP-1 and glucagon receptor dual agonist mazdutide (IBI362) 9 mg and 10 mg in Chinese adults with overweight or obesity: a randomised, placebo-controlled, multiple-ascending-dose phase 1b trial. EClinicalMedicine 2022;54:101691 (PMID 36247927)retrieved 2026-08-17Human trial
- Bays HE et al. Weekly Subcutaneous VK2735 for Weight Management: Phase 2 VENTURE Study. Obesity 2026;34:537-549 (NCT06068946, PMID 41508550)retrieved 2026-08-16Human trial
- Altimmune 2024 Form 10-K — 48-week MOMENTUM phase 2 obesity resultsretrieved 2026-08-17Sponsor results filed with the SEC
- Harrison SA et al. Pemvidutide in MASLD: randomized, double-blind trial (NCT05006885, PMID 39002641)retrieved 2026-08-17Human trial
- Noureddin M et al. Pemvidutide in MASH: 24-week IMPACT phase 2b results (NCT05989711, PMID 41237796)retrieved 2026-08-17Human trial
- Altimmune SEC exhibit — RECLAIM phase 2 topline results in alcohol use disorderretrieved 2026-08-17Phase 2 results in a company SEC filing
- NCT07009860 — RESTORE phase 2 pemvidutide trial in alcohol-associated liver diseaseretrieved 2026-08-17Human trial
- Billings LK et al. Eloralintide for obesity: 48-week Phase 2 trial (PMID 41207310)retrieved 2026-09-07Human trial
- NCT06230523 — 48-week Phase 2 Eloralintide trialretrieved 2026-08-29Human trial
- Wegovy (semaglutide) Prescribing Information, revised 06/2026 — Drugs@FDA NDA 215256/S-025retrieved 2026-08-12FDA label
- Ozempic (semaglutide) injection — FDA-approved Prescribing Information (DailyMed)retrieved 2026-09-13FDA label
- Drugs@FDA approval history — NDA 209637, Ozempic (semaglutide) injectionretrieved 2026-08-12FDA label
- Zepbound (tirzepatide) injection — FDA-approved Prescribing Information (DailyMed)retrieved 2026-09-13FDA label
- Zepbound (tirzepatide) Prescribing Information, revised 02/2026 — Drugs@FDA NDA 217806/S-042retrieved 2026-08-12FDA label
- Mounjaro (tirzepatide) injection — FDA-approved Prescribing Information (DailyMed)retrieved 2026-09-13FDA label
- Drugs@FDA approval history — NDA 215866, Mounjaro (tirzepatide) injectionretrieved 2026-08-12FDA label
- Trulicity (dulaglutide) injection — FDA-approved Prescribing Information (DailyMed)retrieved 2026-08-13FDA label
- Trulicity (dulaglutide) Prescribing Information, revised 03/2026 — Drugs@FDA BLA 125469/S-065retrieved 2026-08-13FDA label
- Victoza (liraglutide) injection — FDA-approved Prescribing Information (DailyMed)retrieved 2026-08-13FDA label
- Victoza (liraglutide) Prescribing Information, revised 10/2025 — Drugs@FDA NDA 022341/S-046retrieved 2026-08-13FDA label
- Saxenda (liraglutide) injection — FDA-approved Prescribing Information (DailyMed)retrieved 2026-08-13FDA label
- Saxenda (liraglutide) Prescribing Information, revised 02/2026 — Drugs@FDA NDA 206321/S-025retrieved 2026-08-13FDA label
- FOUNDAYO (orforglipron) tablet, film coated [Eli Lilly and Company] — DailyMed SPL version 10, published 2026-08-13, revised 07/2026retrieved 2026-09-06FDA label
- Rybelsus and Ozempic (semaglutide) tablets — one FDA-approved Prescribing Information covering both names (DailyMed)retrieved 2026-08-20FDA label
- Rybelsus (semaglutide) tablets Prescribing Information, revised 01/2026 — Drugs@FDA NDA 213051/S-030retrieved 2026-08-13FDA label