Page last checked 2026-09-07

Does a GLP-1 cause burping?

Yes. Wegovy and Zepbound list eructation, the medical term for burping, in their reaction tables. Those rows do not describe the smell of the burps.

What the product trials found

These are separate trials, so their rates cannot rank the medicines.

Wegovy

The 2.4 mg weekly shot, in the weight trials

Wegovy: Burping. Percent of people who reported it, by trial arm.
Dose / group	Rate
Placebo1,261 people	<1%
2.4 mg2,116 people	7%

The label prints the placebo figure as less than 1%

Study group and source

2,116 adults with obesity or overweight took the 2.4 mg shot across three placebo-controlled trials. 1,261 took placebo. The average age was 48 and 71% were women.

Up to 68 weeks, then 7 weeks off the drug

Everything reported by 2 in 100 people or more, and more often than on placebo

Read the product label

All Wegovy side effects

Zepbound

The two placebo-controlled weight trials, dose by dose

Zepbound: Burping. Percent of people who reported it, by trial arm.
Dose / group	Rate
Placebo958 people	1%
5 mg630 people	4%
10 mg948 people	5%
15 mg941 people	5%

Study group and source

2,519 adults with obesity or overweight took Zepbound across two trials. The average age was 47 and the average BMI 37.4. A quarter also had type 2 diabetes.

Up to 72 weeks, then 4 weeks off the drug

Everything reported by 2 in 100 people or more, and more often than on placebo

Read the product label

All Zepbound side effects

Medically reviewed by Jennifer Montecillo, MD · non-practicing medical reviewer

Information checked 2026-09-07

How these findings apply

The compound summaries below omit some reactions found in full product labels. That is why an empty summary row should not be read as a label finding.

The FDA snapshot also includes reports filed under eructation. Those reports do not establish what caused the symptom in one person.

Product labels and FDA report summaries answer different questions. Keep each finding tied to its product; a report share is not a rate among everyone taking the medicine.

Compound summary coverage

Compounds that list it

0 of 42

Only in a combined category

No reaction list in this guide

Best available source

FDA label

Which compound summaries list burping

These short compound summaries do not contain every product-label row. The product guides above include the label findings; the separate FDA table below shows the report snapshot.

◆ Burping across 42 compoundsguide or source for every row

Every compound covered on this site, showing whether it lists burping and at what frequency its own cited source states.
Compound	How it appears	Frequency reported	Source type
TirzepatideZepbound, Mounjaro	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	FDA label
SemaglutideWegovy, Ozempic, Rybelsus	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	FDA label
LiraglutideVictoza, Saxenda	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	FDA label
Retatrutide	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	Human trial
Cagrilintide	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	Human trial
Survodutide	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	Human trial
BPC-157	No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.	—	no human dose shown to work
TesamorelinEgrifta SV, Egrifta WR	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	FDA label
PT-141Vyleesi	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	FDA label
CJC-1295	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	limited human data
Ipamorelin	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	Human trial
TB-500	No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.	—	no human dose shown to work
GHK-Cu	No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.	—	no human dose shown to work
Sermorelin	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	limited human data
MOTS-c	No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.	—	no human dose shown to work
AOD-9604	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	limited human data
NAD+	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	limited human data
Epitalon	No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.	—	no human dose shown to work
Kisspeptin-10	No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.	—	no human dose shown to work
DSIP	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	limited human data
Hexarelin	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	limited human data
IGF-1 LR3	No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.	—	no human dose shown to work
PEG-MGF	No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.	—	no human dose shown to work
LL-37	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	limited human data
KPV	No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.	—	no human dose shown to work
Thymosin alpha-1	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	limited human data
SS-31Forzinity	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	FDA label
Semax	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	limited human data
Selank	No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.	—	no human dose shown to work
Melanotan II	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	limited human data
Mazdutide	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	Human trial
Pinealon	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	limited human data
AHK-Cu	No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.	—	no human dose shown to work
VK2735	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	Human trial
Zenagamtide	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	Human trial
Pemvidutide	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	Human trial
Brenipatide	No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.	—	no human dose shown to work
Eloralintide	Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.	—	Human trial
Enicepatide	No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.	—	no human dose shown to work
Macupatide	No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.	—	no human dose shown to work
MariTide	No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.	—	no human dose shown to work
Petrelintide	No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.	—	no human dose shown to work

These tables summarize selected reaction entries. A missing entry does not mean the full label or all published studies omit it. A summary does not replace the full prescribing information. A pharmacist or clinician can review the complete label alongside the rest of a person’s medicines.

What people reported to the FDA

The first table summarizes labels and published trials. This table shows reports filed with the FDA after the medicines went on sale. Each percentage is the share of reports for that product that mention this symptom—not the share of patients who experienced it.

Each GLP-1 brand in the FDA snapshot, and what share of its reports names this symptom.
Product	Share of its own reports	All reports
Ozempicsemaglutide	below 2.3% of Ozempic reports	66,161 reports
Trulicitydulaglutide	below 2.1% of Trulicity reports	88,332 reports
Rybelsussemaglutide	below 2.1% of Rybelsus reports	7,379 reports
Wegovysemaglutide	below 2.0% of Wegovy reports	21,044 reports
Zepboundtirzepatide	1.9% of Zepbound reports	70,141 reports
Saxendaliraglutide	below 1.9% of Saxenda reports	10,040 reports
Mounjarotirzepatide	1.7% of Mounjaro reports	93,975 reports
Victozaliraglutide	below 1.7% of Victoza reports	44,086 reports

A row reading “below” is not a zero. The snapshot keeps each product’s 25 most-reported terms, so a term missing from that list was either never reported or reported outside the stored list. The cutoff provides an upper bound, not an exact count. Read from FDA on 2026-08-17.

Reports are not rates and a report is not proof the drug did it. How to read this data, and the questions it answers on its own.

3Read deeperWhy it happens, when it appears, and what the evidence shows

Does eructation mean sulfur burps?

Eructation means burping or belching. The label row does not identify an odor, and the FDA term shown here does not separate sulfur burps from other belching.

A finding about burping should not be presented as a measurement of sulfur-smelling burps. That more specific description is not what these rows record.

What the tables say about timing

The reaction tables checked here do not give a timetable for burping to begin or stop. Their percentages describe study groups, not how long one person will have symptoms.

The FDA snapshot counts reports mentioning a term. It does not provide a recovery timeline.

What this page does and does not establish

Read the label findings and the report snapshot separately.

What this page does and does not establish
The claim	What the evidence shows
No label lists burping.	Incorrect. Wegovy and Zepbound list eructation. A short compound summary can omit a row that appears in the full label.
Tirzepatide causes more burping than semaglutide.	The report shares cannot establish that. They do not count everyone who used each medicine.
A dashed report row means no cases occurred.	It means the term was not in that product’s stored top terms. The count may be below the cutoff rather than zero.
The reports confirm sulfur-smelling burps.	The general eructation term does not distinguish odor, so that claim is not supported.

When to discuss burping with a clinician

Report persistent or troubling symptoms, including any pain, vomiting or trouble keeping fluids down. Those details matter more than the label term alone.

ClinicianSevere or lasting abdominal pain needs medical attention. A clinician can assess the symptoms and decide whether treatment needs to change.

Common questions

Are sulfur burps a listed side effect of Zepbound or Mounjaro?

Zepbound lists eructation, meaning burping. That entry does not describe a sulfur smell.

Mounjaro has its own label. Zepbound’s trial figures should not be presented as Mounjaro results. The FDA snapshot uses a general belching term for reports about both products.

Why do the two measured rows matter if the numbers are small?

The stored snapshot includes eructation among the top terms for two products. That describes which reports are visible in this extract; it does not rank the medicines by risk.

Is this the same as the gastroparesis question?

No. Belching and delayed stomach emptying are different report terms. A report containing one does not establish the other, and a report alone does not prove a diagnosis.

What would actually answer this?

The product-label tables already answer whether burping was reported during those trials. They keep the placebo results beside the treatment results.

They do not establish a cause for one person or answer the more specific question about sulfur odor.

Want the full picture for one compound? Open its guide for uses, dosage information, side effects and serious warnings.

Tirzepatide reactions in full, including burping

Information from an approved label behind tirzepatide, apart from burping.

What else semaglutide lists besides burping

Including the semaglutide boxed warning, on the semaglutide page rather than on burping.

Constipation read the same way as burping

8 of 42 pages carry constipation, counted class-wide rather than within burping.

Nausea across every page, as with burping

Which sources name nausea, under what wording and at what frequency, beyond burping.

Find compound information beyond burping

Look up uses, dosing information and side effects relevant to burping.

The burping question, asked about duration

A frequency band counts people rather than days, which is why it cannot answer this, with burping as context

Vial, water and draw for the burping compounds

U-100, U-50 and U-40 barrels each read differently, including burping

Browse symptom questions, including burping

Find other symptom questions alongside burping, with links to the relevant findings.

The whole tirzepatide page, not just burping

Tirzepatide has an approved label, separate from burping.

Every symptom in this section is listed on the symptom questions index.

2primary sources, each with the day we read it — open the documents used on this page

WEGOVY (semaglutide) injection and tablets — DailyMed SPL, sections 5 and 6.1retrieved 2026-09-13FDA label
ZEPBOUND (tirzepatide) injection — DailyMed SPL, sections 5 and 6.1retrieved 2026-09-13FDA label