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Does GLP-1 medication cause hair loss?

Yes. Wegovy and Zepbound both list hair loss in their clinical-trial reaction tables. That does not mean every GLP-1 product has the same findings, or that the medicine explains one person’s hair loss.

What the product trials found

These are separate trials, so their rates cannot rank the medicines.

Wegovy

The 2.4 mg weekly shot, in the weight trials

Wegovy: Hair loss. Percent of people who reported it, by trial arm.
Dose / groupRate
Placebo1,261 people1%
2.4 mg2,116 people3%
Study group and source

2,116 adults with obesity or overweight took the 2.4 mg shot across three placebo-controlled trials. 1,261 took placebo. The average age was 48 and 71% were women.

Up to 68 weeks, then 7 weeks off the drug

Everything reported by 2 in 100 people or more, and more often than on placebo

Read the product label

The 7.2 mg weekly shot, against 2.4 mg and against placebo

Wegovy: Hair loss. Percent of people who reported it, by trial arm.
Dose / groupRate
Placebo303 people1%
2.4 mg304 people3%
7.2 mg1,311 people6%
Study group and source

1,311 adults with obesity took 7.2 mg in two trials. 304 took 2.4 mg and 303 took placebo. Average age 49, average BMI 39.5.

72 weeks

Everything reported by 2 in 100 people or more, and more often than on both 2.4 mg and placebo

Read the product label
All Wegovy side effects

Zepbound

The two placebo-controlled weight trials, dose by dose

Zepbound: Hair loss. Percent of people who reported it, by trial arm.
Dose / groupRate
Placebo958 people1%
5 mg630 people5%
10 mg948 people4%
15 mg941 people5%
Study group and source

2,519 adults with obesity or overweight took Zepbound across two trials. The average age was 47 and the average BMI 37.4. A quarter also had type 2 diabetes.

Up to 72 weeks, then 4 weeks off the drug

Everything reported by 2 in 100 people or more, and more often than on placebo

Read the product label
All Zepbound side effects

Medically reviewed by Jennifer Montecillo, MD · non-practicing medical reviewer

Information checked 2026-09-07

How these findings apply

The product labels provide a fuller answer than the compound summaries below. An omitted reaction in a short summary does not mean the full label omits it.

Wegovy contains semaglutide; Zepbound contains tirzepatide. Their findings belong to those products and study groups. They should not be transferred to Ozempic or Mounjaro just because the active ingredient is the same.

Compound summary coverage

Compounds that list it

0 of 42

Only in a combined category

0

No reaction list in this guide

16

Best available source

FDA label

Which compound summaries list hair loss

These are the reaction entries held in our compound summaries. They do not reproduce every row of each product label. Use the product guides above for the hair-loss findings and their study groups.

◆ Hair loss across 42 compoundsguide or source for every row
Every compound covered on this site, showing whether it lists hair loss and at what frequency its own cited source states.
CompoundHow it appearsFrequency reportedSource type
TirzepatideZepbound, MounjaroNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—FDA label
SemaglutideWegovy, Ozempic, RybelsusNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—FDA label
LiraglutideVictoza, SaxendaNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—FDA label
RetatrutideNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—Human trial
CagrilintideNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—Human trial
SurvodutideNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—Human trial
BPC-157No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.—no human dose shown to work
TesamorelinEgrifta SV, Egrifta WRNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—FDA label
PT-141VyleesiNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—FDA label
CJC-1295Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—limited human data
IpamorelinNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—Human trial
TB-500No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.—no human dose shown to work
GHK-CuNo reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.—no human dose shown to work
SermorelinNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—limited human data
MOTS-cNo reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.—no human dose shown to work
AOD-9604Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—limited human data
NAD+Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—limited human data
EpitalonNo reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.—no human dose shown to work
Kisspeptin-10No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.—no human dose shown to work
DSIPNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—limited human data
HexarelinNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—limited human data
IGF-1 LR3No reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.—no human dose shown to work
PEG-MGFNo reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.—no human dose shown to work
LL-37Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—limited human data
KPVNo reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.—no human dose shown to work
Thymosin alpha-1Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—limited human data
SS-31ForzinityNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—FDA label
SemaxNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—limited human data
SelankNo reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.—no human dose shown to work
Melanotan IINot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—limited human data
MazdutideNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—Human trial
PinealonNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—limited human data
AHK-CuNo reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.—no human dose shown to work
VK2735Not listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—Human trial
ZenagamtideNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—Human trial
PemvidutideNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—Human trial
BrenipatideNo reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.—no human dose shown to work
EloralintideNot listed in this summaryThis short reaction list does not include the symptom. Check the full product label or study for more detail.—Human trial
EnicepatideNo reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.—no human dose shown to work
MacupatideNo reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.—no human dose shown to work
MariTideNo reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.—no human dose shown to work
PetrelintideNo reaction list in this guideThis guide has no reaction entries. That does not establish that no human safety evidence exists.—no human dose shown to work

These tables summarize selected reaction entries. A missing entry does not mean the full label or all published studies omit it. A summary does not replace the full prescribing information. A pharmacist or clinician can review the complete label alongside the rest of a person’s medicines.

What people reported to the FDA

The first table summarizes labels and published trials. This table shows reports filed with the FDA after the medicines went on sale. Each percentage is the share of reports for that product that mention this symptom—not the share of patients who experienced it.

Each GLP-1 brand in the FDA snapshot, and what share of its reports names this symptom.
ProductShare of its own reportsAll reports
Ozempicsemaglutidebelow 2.3% of Ozempic reports66,161 reports
Zepboundtirzepatide2.3% of Zepbound reports70,141 reports
Trulicitydulaglutidebelow 2.1% of Trulicity reports88,332 reports
Rybelsussemaglutidebelow 2.1% of Rybelsus reports7,379 reports
Wegovysemaglutidebelow 2.0% of Wegovy reports21,044 reports
Saxendaliraglutidebelow 1.9% of Saxenda reports10,040 reports
Mounjarotirzepatidebelow 1.7% of Mounjaro reports93,975 reports
Victozaliraglutidebelow 1.7% of Victoza reports44,086 reports

A row reading “below” is not a zero. The snapshot keeps each product’s 25 most-reported terms, so a term missing from that list was either never reported or reported outside the stored list. The cutoff provides an upper bound, not an exact count. Read from FDA on 2026-08-17.

Reports are not rates and a report is not proof the drug did it. How to read this data, and the questions it answers on its own.

3Read deeperWhy it happens, when it appears, and what the evidence shows

What the labels say about weight change

Zepbound’s label describes hair-loss reactions as associated with weight reduction. That is a finding about the trial groups; it does not identify the cause of shedding in one person.

A reported reaction, its possible cause and its treatment are different questions. The label can document the first without settling the other two.

How long does shedding last?

The reaction tables checked here do not give a recovery timetable. They report how often hair loss was recorded in the study groups.

How long shedding lasts depends on its cause. A clinician can review the timing, recent weight changes, diet, other symptoms and medicines.

What the evidence shows—and what remains unknown

The product labels report hair loss, but there are limits to what those findings explain.

What the evidence shows—and what remains unknown
The claimWhat the evidence shows
Hair loss was reported during treatment.Supported for Wegovy and Zepbound. Their own reaction tables include hair loss, with a placebo group for context.
The medicine caused my hair loss.The tables cannot establish a cause for one person. Other changes may need to be considered.
All products with the same ingredient have the same rate.Not supported. Dose, treatment form and study group can differ between products.
The table predicts how soon hair will grow back.Not supported. These reaction tables do not provide a recovery timetable.

Discuss new hair loss with a clinician

A clinician can review possible causes and whether further checks are needed. Bring the product name and a description of when the shedding began.

ClinicianA reaction listed on a label does not establish your diagnosis. Your clinician can review it alongside your other medicines and recent health changes.

Common questions

Is hair loss listed as a side effect of Ozempic or Wegovy?

Wegovy’s label lists hair loss. This finding should not be presented as an Ozempic result: the products have separate labels, doses and study groups.

Check the guide for the product you use. An omitted entry in a compound summary is not a finding that hair loss cannot happen.

Is it the medication or the weight loss?

Zepbound’s label associates the reported hair loss with weight reduction. That does not settle the cause for one person.

A clinician can review the timing and other possible causes.

How long does it last, and does hair grow back?

These reaction tables do not report a recovery timetable. The outlook depends on the cause of the shedding.

Do the different GLP-1 compounds differ on this?

The product labels contain different study groups and doses. Their separate reaction rates do not provide a fair ranking of which medicine causes less hair loss.

Would supplements or a higher protein intake prevent it?

The reaction tables do not test a supplement or protein plan to prevent hair loss. A clinician or dietitian can assess whether nutrition needs attention in your case.

Why do so many pages give a percentage for this?

Some percentages come from real product labels. To interpret one, check the product, dose, study group and placebo result.

A percentage from a weight-management trial should not be presented as a rate for every person taking the same active ingredient.

Is muscle loss a different question from this one?

Yes. A hair-loss entry reports a reaction. Changes in lean mass are body-composition measurements, which require a different kind of evidence.

Want the full picture for one compound? Open its guide for uses, dosage information, side effects and serious warnings.

Every symptom in this section is listed on the symptom questions index.

2primary sources, each with the day we read it — open the documents used on this page