Skip to main content

Page last checked

Reconstitution · Cagrilintide

Cagrilintide reconstitution calculator

Pick the vial, the water you added and the dose. Get the exact draw in units for the syringe in your hand.

Step 1 of 4

  1. How many mg are in your vial?
    Vial amounttotal mg in the calculation
  2. How many mL of water did you add?
  3. What dose do you want to convert?
  4. Which syringe are you using?
Draw to
48.0units

0.48 mL in the syringe · 4 calculated doses from this amount

48.0 units on a U-100 insulin syringe · 1 mL · lines every 2 units, which is 0.48 milliliters. The draw lands on a syringe line.

Easy to read on this syringe. The calculated volume matches the 48-unit line. No rounding is needed.

10 mg ÷ 2 mL = 5.00 mg/mL
→ 50 mcg/unit · 2.4 mg = 0.480 mL = 48.0 units

Your address is used to send this one card. The email also includes an optional link for updates when our data changes. Nothing else is sent unless you choose that link, and you can unsubscribe anytime.

Show the math and syringe details

Can this syringe show the result clearly?

Easy to read on this syringe. 48.0 u is exactly the 48-unit line on a U-100 — no rounding error at all.

Want an easier syringe number?

This setup is already easy to read. Changing the water between 0.5 and 3 mL would not put 2.4 mg closer to a line on this U-100 syringe.

Adding more water makes the mixture less concentrated, so the same dose uses more syringe units. It does not change how much peptide is in the vial.

This setup is in the address bar — every input is part of the link.

Educational math, not medical advice — dosing decisions belong to a licensed clinician. The available tabs also show supply calculations and any sourced schedule.

How to use the calculator

  1. 1

    Enter the amount in the vial

    Use the total mg printed on your Cagrilintide vial.

  2. 2

    Enter the water you added

    Use the amount of water added to that vial, in mL.

  3. 3

    Enter the dose you want to convert

    Choose mg or mcg, then match the result to your syringe.

Cagrilintide is a weekly shot in weight-loss studies. It copies amylin, a natural signal that helps you feel full after eating. Sellers offer unapproved cagrilintide for weight loss, sometimes paired with semaglutide under the name CagriSema.

A phase 2 trial found more average weight loss at higher doses. It has moved into phase 3 trials with semaglutide. Cagrilintide does not have FDA approval.

Examples using 10 mg of Cagrilintide

Each row uses 10 mg and the liquid volume shown. Dividing the amount by that volume gives the calculated concentration. The rows are arithmetic examples, not alternative product preparations.

◆ How liquid volume changes the resultdose used: 2.4 mg

With 1 mL bacteriostatic water

24.0 units

Concentration
10.00 mg/mL
Each U-100 unit
100.0 mcg
Syringe volume
0.240 mL
Nearest line
Exactly 24 units

With 2 mL bacteriostatic water

48.0 units

Starting example
Concentration
5.00 mg/mL
Each U-100 unit
50.0 mcg
Syringe volume
0.480 mL
Nearest line
Exactly 48 units

The amount, liquid volume and dose shown here are the calculator’s starting example for Cagrilintide. Replace them with your own values. Every result in the table is calculated from those inputs.

Drawn from once a week at 2.4 mg, a 10 mg vial yields 4 doses — about 4.0 weeks of supply. No storage limit is assigned to this example. Follow the dispensing label for the specific product.

Cagrilintide: read the volume alongside the dose

The cagrilintide examples use the same amount of medicine at different concentrations. The draw changes with the vial and water inputs. A longer draw means more liquid; it does not, by itself, mean more medicine.

Open the mixing details3 notes

Milligrams and syringe units answer different questions

Milligrams describe the amount of cagrilintide entered in the dose field. Syringe units describe how much liquid contains that amount at the calculated concentration. Keep both figures together when reading a result or comparing the worked examples.

A unit count copied from another setup can represent a different amount of cagrilintide. Matching the compound name is not enough: the vial amount, liquid volume and syringe scale must match too. The calculator shows those inputs beside the answer.

Why changing the water changes the draw

With the vial amount and target dose held fixed, more water produces a larger calculated volume. Less water produces a smaller volume. The amount of cagrilintide in that result stays the same, but the liquid volume does not.

This relationship explains the differences between rows in the table. It does not choose a preparation method or establish that two injection volumes are interchangeable. A calculation can describe a mixture without being instructions to make it.

Check capacity after changing an input

The opening cagrilintide examples fit within the reference syringe. That statement applies to the displayed inputs. Increasing the entered dose or changing the concentration changes the volume needed, so the result must be checked again.

If the calculated volume exceeds the selected syringe capacity, the tool flags that limit. The warning does not tell you to split the amount into multiple draws or to add less water. It identifies a setup the selected syringe cannot hold.

Cagrilintide alone is different from a combination treatment

The dose-finding study tested cagrilintide alone at several weekly doses. CagriSema adds semaglutide to it. These are different treatments, so a result or dose from one does not stand in for the other.

Read the supporting evidence3 supporting notes

The study included a gradual increase

Participants did not simply start at every target amount shown in the results. The trial included a period of dose increases before ongoing treatment. Its weekly dose groups were compared with placebo and with liraglutide.

One ingredient field cannot describe a blend

This tool treats the entered mass as cagrilintide alone. A blend contains other ingredients too. The total powder weight cannot tell you how much of each one is in a draw. Each ingredient needs its own stated amount.

Trial dosing does not set a mixed-vial shelf life

A weekly trial schedule is not a storage instruction for a different preparation. Calculating how many draws a vial contains cannot establish how long its contents remain usable after mixing.

Units to dose at 5.00 mg/mL

Mix 10 mg into 2 mL and one U-100 unit carries 50.0 mcg. The table shows how much peptide is in each numbered syringe line. These are conversion examples, not suggested doses.

Open the unit conversion table10 rows
Numbered U-100 syringe lines converted to volume and mass at 5.00 milligrams per milliliter.
U-100 lineVolumeMass (mcg)Mass (mg)
10 u0.10 mL500 mcg0.5 mg
20 u0.20 mL1,000 mcg1 mg
30 u0.30 mL1,500 mcg1.5 mg
40 u0.40 mL2,000 mcg2 mg
50 u0.50 mL2,500 mcg2.5 mg
60 u0.60 mL3,000 mcg3 mg
70 u0.70 mL3,500 mcg3.5 mg
80 u0.80 mL4,000 mcg4 mg
90 u0.90 mL4,500 mcg4.5 mg
100 u1.00 mL5,000 mcg5 mg

How the math works

  1. Concentration — divide the amount entered by the liquid volume used in the calculation: mg ÷ mL = mg/mL. This tells you how many mg are in each mL.
  2. Volume — the dose divided by that concentration: dose ÷ (mg/mL) = mL.
  3. Units — on a U-100 syringe one unit is 0.01 mL, so mL × 100 = units. A U-40 unit is 0.025 mL, so the wrong barrel is a 2.5× error. That is why the calculator asks which one you have.
  4. Rounding gap — the exact draw against the nearest syringe line: |exact − nearest line| ÷ exact × 100 = % difference.

Medically reviewed by Kenneth Montecillo, MD2026-09-07open the primary sources

Useful guides for this calculation

The math is only one part of the question. These guides cover the compound, published doses, side effects, mixing steps and supplies.

Questions readers ask

How to reconstitute 30 mg of peptides?

30 mg is more powder than either cagrilintide vial here holds, and the operation is the same one. Divide milligrams by milliliters: 30 mg in 1 mL is 30 mg/mL, in 2 mL it is 15, in 3 mL it is 10.

At 30 mg/mL one U-100 unit carries 300 micrograms. The 2.4 mg carried into phase 3 would be 8 units, and a single misread mark moves it by 300 micrograms. Strong solutions punish small errors.

How much water to add to reconstitute peptides?

More water never changes the milligrams. It spreads them through more liquid, so the same dose becomes a longer draw that is easier to read.

Cagrilintide is where that advice meets its limit. Its studied range reaches 4.5 mg, and the 5 mg vial in 2 mL puts that at 180 units — nearly two full barrels. Here the smaller volume is what keeps one dose in one pull.

How many units of cagrilintide?

It depends on the vial and the water, and this page’s four pairings give four answers for one dose. The 2.4 mg carried into phase 3 draws 24 units from 10 mg in 1 mL. It draws 48 from 10 mg in 2 mL or 5 mg in 1 mL, and 96 from 5 mg in 2 mL.

All four are the same injection; only the liquid around it changed. A unit count quoted without its vial size and its water volume describes somebody else’s glass.

How to mix cagrilintide with tirzepatide?

No published study has given cagrilintide and tirzepatide to anyone together. The partner cagrilintide actually went into phase 3 with is semaglutide, co-formulated in one injection as CagriSema.

When two peptides share a vial, whoever filled it fixed the ratio. Moving the plunger moves both at once, so you set one amount and simply receive the other. That constraint is arithmetic, and it says nothing about whether the pair has been tested.

1primary source, each with the day we read it — open the documents used on this page