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Reconstitution · Cagrilintide

Cagrilintide reconstitution calculator

Pick the vial, the water you added and the dose. Get the exact draw in units for the syringe in your hand.

Step 1 of 4

  1. How many mg are in your vial?
    Vial strengthamount printed on the vial
  2. How many mL of water did you add?
  3. What dose do you want to convert?
  4. Which syringe are you using?
Draw to
48.0units

0.48 mL · 5.00 mg/mL · 50 mcg per unit · 4 doses per vial

48.0 units on a U-100 insulin syringe · 1 mL · lines every 2 units, which is 0.48 milliliters. The draw lands on a syringe line.

Easy to read on this syringe. Draw to the 48-unit line. No rounding is needed.

10 mg ÷ 2 mL = 5.00 mg/mL
50 mcg/unit · 2.4 mg = 0.480 mL = 48.0 units

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Show the math and syringe details

Can this syringe show the result clearly?

Easy to read on this syringe. 48.0 u is exactly the 48-unit line on a U-100 — no rounding error at all.

Want an easier syringe number?

This setup is already easy to read. Changing the water between 0.5 and 3 mL would not put 2.4 mg closer to a line on this U-100 syringe.

Adding more water makes the mixture less concentrated, so the same dose uses more syringe units. It does not change how much peptide is in the vial.

This setup is in the address bar — every input is part of the link.

Educational math, not medical advice — dosing decisions belong to a licensed clinician. The tabs above also plan a schedule week by week and count how many doses one vial holds.

How to use the calculator

  1. STEP 1

    Enter the amount in the vial

    Use the total amount printed on the vial, in mg.

  2. STEP 2

    Enter the water you added

    Use the amount of water added to that vial, in mL.

  3. STEP 3

    Enter the dose you want to convert

    Choose mg or mcg, then match the result to your syringe.

Cagrilintide is a weekly shot in weight-loss studies. It copies amylin, a natural signal that helps you feel full after eating. Sellers offer unapproved cagrilintide for weight loss, sometimes paired with semaglutide under the name CagriSema.

A phase 2 trial found more average weight loss at higher doses. It has moved into phase 3 trials with semaglutide. Cagrilintide does not have FDA approval.

Examples using a 10 mg Cagrilintide vial

Each row starts with the same 10 mg vial and changes only the amount of water. More water makes the mixture less concentrated, so the same dose uses more syringe units.

◆ How the water amount changes the resultdose used: 2.4 mg
For a 10 milligram vial: bacteriostatic water added, resulting concentration, micrograms per U-100 unit, and the draw for a 2.4 mg dose.
Water addedConcentrationPer U-100 unitDraw for 2.4 mgNearest syringe line
1 mL10.00 mg/mL100.0 mcg24.0 u · 0.240 mLexactly 24 u
2 mL5.00 mg/mL50.0 mcg48.0 u · 0.480 mLexactly 48 u

The vial, water and dose shown here are the calculator’s starting example for Cagrilintide. Replace them with your own values. Every result in the table is calculated from those inputs.

Drawn from once a week at 2.4 mg, a 10 mg vial yields 4 doses — about 4.0 weeks of supply. No cited source says how long the mixed vial keeps, so no storage window is shown.

Large draws, because the milligrams are large

Cagrilintide fills more of the barrel than most things here. That says how much powder the dose is. It says nothing about how strong the dose is.

3Open the mixing details 3 notes

It copies a different hormone from its neighbors

The compounds either side of this one on the site copy gut hormones. Cagrilintide copies amylin, which the pancreas releases to end a meal. It sits here because you mix it the same way, not because it behaves the same way.

The practical consequence is on the scale. Its studied range reaches higher in milligrams than semaglutide’s does. A dose that sounds alarming beside a semaglutide figure is ordinary here, and comparing milligrams across compounds compares nothing.

A long draw is a dilute vial, not a big dose

A plunger drawn most of the way up the barrel looks dramatic beside a research peptide’s four or five units. It only means the powder is spread through a lot of water.

Halve the water and the same dose reads half as far up. Identical milligrams, identical injection, different picture. The number of units is a fact about your mixing and nothing else.

The mistake: reaching for the larger water volume by habit

More water is the usual advice on this site. It spreads small doses over more marks. Cagrilintide’s doses are not small.

With the smaller vial and the larger volume, the top of the studied range runs past the end of a U-100 barrel. It then has to come out in two pulls, and two pulls is two chances to misread one dose. Here, less water keeps a dose in a single draw.

The starting quantity is the arm that moved on, and it did not move on alone

The number the tool loads with is the arm the developers carried into their later trials. Those trials do not study it by itself. They study it combined with another compound, in one injection, under a name of its own.

5Read the supporting evidence 5 supporting notes

The number’s pedigree is a combination; the vial is not

The trial’s safety notes make this distinction clear. The later program tests the combination, not cagrilintide alone.

Two vial sizes, neither of them cut for the bottom of the range

Two vial sizes are documented, one twice the other. Both contain many times the smallest amount tested in the trial.

What these arms were measured against

This trial included both a placebo group and a named comparator, making the result easier to interpret than an uncontrolled dose series.

Nothing on this page dates the mixed vial

No cited source says how long a mixed vial lasts, so no storage window is shown.

What the published data cannot tell you

It cannot represent a combined injection. It converts one compound at a time, because one compound is what the vial holds.

Units to dose at 5.00 mg/mL

Mix 10 mg into 2 mL and one U-100 unit carries 50.0 mcg. The table shows how much peptide is in each numbered syringe line. These are conversion examples, not suggested doses.

10Open the unit conversion table 10 rows
Numbered U-100 syringe lines converted to volume and mass at 5.00 milligrams per milliliter.
U-100 lineVolumeMass (mcg)Mass (mg)
10 u0.10 mL500 mcg0.5 mg
20 u0.20 mL1,000 mcg1 mg
30 u0.30 mL1,500 mcg1.5 mg
40 u0.40 mL2,000 mcg2 mg
50 u0.50 mL2,500 mcg2.5 mg
60 u0.60 mL3,000 mcg3 mg
70 u0.70 mL3,500 mcg3.5 mg
80 u0.80 mL4,000 mcg4 mg
90 u0.90 mL4,500 mcg4.5 mg
100 u1.00 mL5,000 mcg5 mg

How the math works

  1. Concentration — divide the amount in the vial by the water you added: mg ÷ mL = mg/mL. This tells you how many mg are in each mL.
  2. Volume — the dose divided by that concentration: dose ÷ (mg/mL) = mL.
  3. Units — on a U-100 syringe one unit is 0.01 mL, so mL × 100 = units. A U-40 unit is 0.025 mL, so the wrong barrel is a 2.5× error. That is why the calculator asks which one you have.
  4. Rounding gap — the exact draw against the nearest syringe line: |exact − nearest line| ÷ exact × 100 = % difference.

Medically reviewed by Jennifer Montecillo, MD · non-practicing medical reviewerReviewed 2026-08-17open the primary sources

Useful guides for this calculation

The math is only one part of the question. These guides cover the compound, published doses, side effects, mixing steps and supplies.

Questions readers ask

How to reconstitute 30 mg of peptides?

30 mg is more powder than either cagrilintide vial here holds, and the operation is the same one. Divide milligrams by milliliters: 30 mg in 1 mL is 30 mg/mL, in 2 mL it is 15, in 3 mL it is 10.

At 30 mg/mL one U-100 unit carries 300 micrograms. The 2.4 mg carried into phase 3 would be 8 units, and a single misread mark moves it by 300 micrograms. Strong solutions punish small errors.

How much water to add to reconstitute peptides?

More water never changes the milligrams. It spreads them through more liquid, so the same dose becomes a longer draw that is easier to read.

Cagrilintide is where that advice meets its limit. Its studied range reaches 4.5 mg, and the 5 mg vial in 2 mL puts that at 180 units — nearly two full barrels. Here the smaller volume is what keeps one dose in one pull.

How many units of cagrilintide?

It depends on the vial and the water, and this page’s four pairings give four answers for one dose. The 2.4 mg carried into phase 3 draws 24 units from 10 mg in 1 mL. It draws 48 from 10 mg in 2 mL or 5 mg in 1 mL, and 96 from 5 mg in 2 mL.

All four are the same injection; only the liquid around it changed. A unit count quoted without its vial size and its water volume describes somebody else’s glass.

How to mix cagrilintide with tirzepatide?

No published study has given cagrilintide and tirzepatide to anyone together. The partner cagrilintide actually went into phase 3 with is semaglutide, co-formulated in one injection as CagriSema.

When two peptides share a vial, whoever filled it fixed the ratio. Moving the plunger moves both at once, so you set one amount and simply receive the other. That constraint is arithmetic, and it says nothing about whether the pair has been tested.

1primary source, each with the day we read it — open the documents used on this page