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How-to · reconstitution
Put 1 mL of bacteriostatic water into the 10 mg Cagrilintide vial. That makes 10.00 mg/mL. A 2.4 mg dose is then 24.0 units on a U-100 syringe.
That volume is the one that lands the draw on a syringe line, so the reading can be checked by eye. More water makes a weaker mix and a bigger draw. Less water makes a stronger mix and a smaller one. The amount of Cagrilintide in the glass never changes. Only the number of marks it takes does.
Cagrilintide is a weekly shot in weight-loss studies. It copies amylin, a natural signal that helps you feel full after eating.
| Water added | Concentration | Per U-100 unit | Example: 2.4 mg = |
|---|---|---|---|
| 1 mL | 10.00 mg/mL | 100 mcg | 24.0 units |
| 2 mL | 5.00 mg/mL | 50 mcg | 48.0 units |
Straight arithmetic: concentration = 10 mg ÷ water, and 1 U-100 unit = 0.01 mL. The example column shows the math at 2.4 mg; it is not a dose recommendation.
Which volume to use is a practical choice rather than a dose. Pick the one that puts your draw somewhere you can actually read it on the syringe. The flags in the last column mark where that fails. “Hard to measure” means the draw is too small to judge by eye. “Won’t fit” means it is bigger than one U-100 syringe holds.
The table above uses one worked example. These are the published quantities, converted into marks on a U-100 barrel at each water volume for a 10 mg vial. Where a quantity was never studied by injection, the row says so.
0.3–4.5 mg once weekly, under the skin. (phase 2 dose-finding arms, reached by 4-week escalation steps).
| Water added | Concentration | Draw, low to high |
|---|---|---|
| 1 mL | 10.00 mg/mL | 3.0 to 45.0 units |
| 2 mL | 5.00 mg/mL | 6.0 to 90.0 units |
Human trialLau DCW et al. Once-weekly cagrilintide for weight management: dose-finding phase 2 trial. Lancet 2021;398:2160-72 (PMID 34798060) · retrieved 2026-08-17
Twice the powder of the smaller vial, so the same amount draws half as far up the barrel at the same water volume. Four doses instead of two, and neither listed volume runs past the end of a syringe.
Mixed into the larger listed volume, this vial produces exactly the strength and draw the smaller vial produces at the smaller volume. The two pages print the same number for different glass.
So a unit count recognized from elsewhere confirms nothing. It is consistent with two different vials, and only the strength printed on the one in your hand settles which.
No published source says how long a mixed vial keeps, so the dose count cannot be converted into a safe storage period.
Four draws is what the powder divides into. How long you have to take them is not something this page can tell you.
Because the solution is stronger at any given volume, the draws land lower on the barrel and further from its top. Neither listed volume overruns the syringe here.
On the smaller vial one of them nearly does. So on this compound the bigger vial is the more forgiving purchase, not the more wasteful one.
The table shows the offered water volumes. The calculator does the same arithmetic for any volume and any syringe, and shows its working line by line.
Open the Cagrilintide calculator →The arithmetic on this page is only half the question. These are the pages that carry the other half.