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Brand guide · Tirzepatide

What is Zepbound?

Zepbound is a brand of Tirzepatide. FDA has approved it for 2 uses. People take it once weekly, at any time of day. The first labeled dose is 2.5 mg. The highest is 15 mg.

Source: Current FDA label, checked 2026-08-12

What matters first

Medicine
Tirzepatide
How often
Once weekly, at any time of day
Starting dose
2.5 mg
Highest labeled dose
15 mg

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Approved uses

What is Zepbound approved to treat?

Adults with obesity, or with overweight plus at least one related health condition.

Labeled maintenance: 5 mg, 10 mg or 15 mg once weekly

Adults with obesity and moderate to severe sleep apnea.

Labeled maintenance: 10 mg or 15 mg once weekly

Not an approved use: FDA has not approved Zepbound for type 2 diabetes or anyone under 18.

The product itself

How Zepbound comes

Single-dose pen

2.5, 5, 7.5, 10, 12.5 and 15 mg per 0.5 mL

1 dose

Single-dose vial

2.5, 5, 7.5, 10, 12.5 and 15 mg per 0.5 mL

1 dose

Multi-dose vial

10 to 60 mg per 2.4 mL, delivering 2.5 to 15 mg per 0.6 mL dose

4 doses

Single-patient-use KwikPen

10 to 60 mg per 2.4 mL, delivering 2.5 to 15 mg per dose

4 doses

Eli Lilly and Company makes Zepbound under NDA 217806. The label says it is given as a shot under the skin.

Same medicine, different label

How is Zepbound different from Mounjaro?

Two brand names use this drug. Zepbound is the one for weight-related care. Mounjaro is the one for type 2 diabetes. Their dose plans are not the same.

Read the Mounjaro overview
4primary sources, each with the day we read it — open the documents used on this page

Medically reviewed by Jennifer Montecillo, MD · non-practicing medical reviewer

Zepbound is a registered brand name. HealthspanLedger is not affiliated with or endorsed by Eli Lilly and Company. This page summarizes public FDA records and does not give medical advice.