Page last checked 2026-09-07

How-to · reconstitution

How to reconstitute Semax 10 mg

In this example, 1 mL of bacteriostatic water in a 10 mg Semax vial gives 10.00 mg/mL. An example 6 mg amount is then 60.0 units on a U-100 syringe.

This example lands on a syringe line. More water makes a weaker mix and a bigger draw. Less water makes a stronger mix and a smaller one. The amount of Semax stays the same. Use the diluent and volume specified for your product; the arithmetic alone does not choose them.

What matters first

Example water volume: 1 mL
Resulting strength: 10.00 mg/mL
Example 6 mg dose: 60.0 U-100 units

How much bacteriostatic water for a 10 mg Semax vial?

◆ Unique to the 10 mg vialU-100 example draws

Water added	Concentration	Per U-100 unit	Example: 6 mg =
1 mL	10.00 mg/mL	100 mcg	60.0 units
2 mL	5.00 mg/mL	50 mcg	120.0 unitswon’t fit

Straight arithmetic: concentration = 10 mg ÷ liquid volume, and 1 U-100 unit = 0.01 mL. The example column shows the math at 6 mg; it is not a dose recommendation.

The table compares possible concentrations; it does not establish which diluent or volume suits your product. Follow its dispensing instructions.

“Hard to measure” means the example draw is below two U-100 units. “Won’t fit” means it exceeds this syringe’s capacity.

Semax 10 mg vial: example mixing volumes. Each row is what that amount draws on a U-100 syringe. 1 mL makes 10.00 mg/mL, or 100 mcg a unit, and 6 mg is 60 units. 2 mL makes 5.00 mg/mL, or 50 mcg a unit, and 6 mg is more than one barrel holds. The barrel drawn here is filled to 60 units, the draw at 1 mL. The sum is 10 mg divided by the liquid volume. One U-100 unit is 0.01 mL. — The 10 mg vial at 1 mL on a U-100 barrel. 6 mg fills to 60.0 units, at 10.00 mg/mL.

Medically reviewed by Kenneth Montecillo, MD2026-09-07open the primary sources

What is Semax?

Semax is a peptide seven amino acids long, copied from a short stretch of a stress hormone. It carries none of that hormone’s own activity.

How many units is a documented dose from this vial?

The table above uses one worked example. These are the published quantities, converted into marks on a U-100 barrel at each listed liquid volume for a 10 mg vial. Where a quantity was never studied by injection, the row says so.

6 mg — studied in a trial

6 mg a day, in two courses of ten days separated by twenty days, into the nose. (110 patients at different stages after an ischemic stroke, mean age 58; the study also reported a brain-growth-factor marker in the blood rising alongside recovery scores).

Water added	Concentration	Draw
1 mL	10.00 mg/mL	60.0 units
2 mL	5.00 mg/mL	120.0 unitswon’t fit

limited human dataGusev EI, Martynov MY, Kostenko EV, Petrova LV, Bobyreva SN. [The efficacy of semax in the tretament of patients at different stages of ischemic stroke]. Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(3 Vyp 2):61-68 — 110 patients, two ten-day courses of 6000 mcg a day separated by twenty days. Russian; read here through the English abstract indexed in PubMed · retrieved 2026-08-13

12 mg — studied in a trial

12 mg a day as a 1% solution, in two courses of ten days two weeks apart, into the nose. (27 patients; the report calls itself open-label. It states that Semax did not change the course of the disease, with a difference showing only on a quality-of-life total).

Water added	Concentration	Draw
1 mL	10.00 mg/mL	120.0 unitswon’t fit
2 mL	5.00 mg/mL	240.0 unitswon’t fit

limited human dataSerdiuk AV, Levitskii GN, Miasoedov NF, Skvortsova VI. [The study of chronic partial denervation and quality of life in patients with motor neuron disease treated with semax]. Zh Nevrol Psikhiatr Im S S Korsakova. 2007;107(4):29-39 — 27 patients given 12 mg a day intranasally as a 1% solution in two ten-day courses. The abstract calls it open-label and reports that Semax did not influence the course of the disease. Russian; read through the indexed English abstract · retrieved 2026-08-13

The smaller Semax vial, where the thinner mix runs out of barrel

Two strengths are documented, and this is the smaller one. At the worked amount it contains one draw, and only one of the two water options fits a U-100 syringe.

3Read the full vial record — 3 notes

Why one of the two rows fails

The published worked amount is large relative to this vial. With more water, one draw exceeds the capacity of a U-100 syringe.

The more concentrated example fits the illustrated barrel. That comparison identifies a volume limit; it does not make either example an approved or tested preparation for injection.

One draw, against a course that ran for days

The study used the worked amount daily in two ten-day periods separated by a break. This vial contains one complete portion at that amount.

The portion count is much smaller than the number of administrations in that study. Matching the total mass would still not reproduce the studied preparation, its route or its delivery method.

It is also arithmetic about a product given as nasal drops from a licensed bottle, which this powder is not. The mass matches and nothing else about the two does.

A smaller powder example is still a different product

The vial example converts one stated drug mass into concentration and draw volume. It does not establish that the powder should be mixed, injected or used as a substitute for the studied nasal preparation.

Increasing the vial strength gives more theoretical portions but does not resolve the route difference. A larger quantity cannot supply the product instructions or clinical evidence needed to make that substitution.

Neither worked strength identifies the licensed nasal product used in the study. The figures depend on the stated inputs and do not independently confirm the identity, content or quality of another preparation.

How do you mix it, step by step?

Wipe both stoppers with an alcohol swab and let them dry.
Check the product’s mixing instructions for the correct diluent and volume before drawing it up.
Let the water run slowly down the inside wall of the Semax vial, rather than jetting it onto the powder.
Follow the product’s instructions for mixing and checking the solution before use. Do not assume every powder uses the same method.
Store it as the dispensing label directs. What happens after mixing differs by product — some labels direct against refrigerating the mixed solution at all.

What if your water volume is not on the table?

The calculator lets you enter your product’s vial strength and mixing volume, then shows the arithmetic for your syringe.

Open the Semax calculator →

Where to read next about Semax

The arithmetic on this page is only half the question. These are the pages that carry the other half.

How semax differs from the rest of its class

No published human dosing schedule was found for semax.

Every calculator on this site, semax and the rest

Every intermediate value is printed, for semax or any other vial.

Primary regulatory documents, including semax

Every URL was fetched and live on its retrieval date, semax or otherwise.

Browse semax guides by vial strength

Explore water volumes, concentrations and example draws alongside semax.

2primary sources, each with the day we read it — open the documents used on this page