With 2 mL bacteriostatic water
10.0 units
Page last checked
Reconstitution · KPV
KPV dosage calculator
Pick the vial, the water you added and the dose. Get the exact draw in units for the syringe in your hand.
Step 1 of 4
- total mg in the calculation
- mL used in the calculation
- mcg
This vial holds 10,000 mcg in total.
- match the size on the package
U-100 insulin syringe · 1 mL · lines every 2 units · 1 unit = 0.01 mL
Draw to
15.0units
15.0 units on a U-100 insulin syringe · 1 mL · lines every 2 units, which is 0.15 milliliters. The nearest syringe line is 16 units.
10 mg ÷ 3 mL = 3.33 mg/mL
→ 33 mcg/unit · 500 mcg = 0.150 mL = 15.0 units
→ 33 mcg/unit · 500 mcg = 0.150 mL = 15.0 units
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How to use the calculator
- 1
Enter the amount in the vial
- 2
Enter the water you added
- 3
Enter the dose you want to convert
KPV is three amino acids — lysine, proline, valine. They are the tail end of the hormone that controls skin pigment. It is sold for gut inflammation, and for eczema and other inflamed skin.
The interest behind that is real but narrow. In mice given colitis chemically, and in colon cells in a dish, it quietens inflammatory signaling. The FDA states it has found no data on any person receiving it, by any route.
No completed controlled human trial has shown which dose works for KPV. There is no study-backed human dosing program to publish. Animal quantities are not converted into a human recommendation.
no human dose shown to work
Examples using 10 mg of KPV
Each row uses 10 mg and the liquid volume shown. Dividing the amount by that volume gives the calculated concentration. The rows are arithmetic examples, not alternative product preparations.
◆ How liquid volume changes the resultdose used: 500 mcg
With 3 mL bacteriostatic water
15.0 units
| Bacteriostatic water | Concentration | Per U-100 unit | Draw for 500 mcg | Nearest syringe line |
|---|---|---|---|---|
| 2 mL | 5.00 mg/mL | 50.0 mcg | 10.0 u · 0.100 mL | exactly 10 u |
| 3 mL | 3.33 mg/mL | 33.3 mcg | 15.0 u · 0.150 mL | 16 u · 6.7% off |
The amount, liquid volume and dose shown here are the calculator’s starting example for KPV. Replace them with your own values. Every result in the table is calculated from those inputs.
KPV: a readable syringe result does not establish a human dose
The KPV guide does not identify an established human dose. Its evidence discussion and the calculator’s starting example serve different purposes. A volume that is straightforward to display is not evidence that the entered amount works.
Open the mixing details3 notes
Research context stays separate from the example
The guide discusses preclinical work, including gut-cell and mouse research. Those studies address their own experimental questions. They do not establish an amount, preparation or schedule for a person.
A statement about missing human exposure data also needs its source and scope. It should not be expanded into a claim that nobody has ever received KPV. The calculator makes no such determination; its arithmetic does not count as human evidence.
The vial label is an input, not a test result
The calculation starts from the vial amount entered. It cannot identify the contents, test purity or measure strength. A familiar name or the appearance of a preparation cannot supply those missing measurements.
This limitation does not depend on assumptions about who supplied a vial or what it cost. The arithmetic is conditional on the inputs. If they do not describe the preparation accurately, the displayed concentration and draw will not describe it accurately either.
Read the amount alongside the syringe units
The KPV presets include different vial strengths. At the same liquid volume, the stronger vial requires a smaller draw for the same amount. The same number of syringe units would therefore represent different amounts across those setups.
The starting examples can be displayed within the barrel, but that does not establish safety or make rounding irrelevant. The output reports the current target and marked reading. It does not select an amount or a treatment schedule from how easy the scale looks.
KPV’s cited evidence does not supply a human injection dose
The cited FDA review and laboratory papers do not provide a supported human dose for the tool. The material reviewed includes topical preparations and preclinical experiments. Those contexts do not establish a schedule for an injected vial.
Read the supporting evidence2 supporting notes
A concentration in a dish is not a dose in a person
Cell experiments state how much KPV was in the liquid around the cells. That is not an amount given to a person. To translate it, we would need to know how it enters, spreads through and leaves the body. Vial volume does not answer those questions.
The arithmetic can remain useful while the dose is unknown
The tool can explain the concentration produced by the mass and water entered. Its example does not fill the evidence gap or establish an injection route. The FDA assessment found no human exposure data to answer those questions.
A concentration in a dish is not a dose in a person
Cell experiments state how much KPV was in the liquid around the cells. That is not an amount given to a person. To translate it, we would need to know how it enters, spreads through and leaves the body. Vial volume does not answer those questions.
The arithmetic can remain useful while the dose is unknown
The tool can explain the concentration produced by the mass and water entered. Its example does not fill the evidence gap or establish an injection route. The FDA assessment found no human exposure data to answer those questions.
Units to dose at 3.33 mg/mL
Mix 10 mg into 3 mL and one U-100 unit carries 33.3 mcg. The table shows how much peptide is in each numbered syringe line. These are conversion examples, not suggested doses.
Open the unit conversion table10 rows
| U-100 line | Volume | Mass (mcg) | Mass (mg) |
|---|---|---|---|
| 10 u | 0.10 mL | 333 mcg | 0.333 mg |
| 20 u | 0.20 mL | 667 mcg | 0.667 mg |
| 30 u | 0.30 mL | 1,000 mcg | 1 mg |
| 40 u | 0.40 mL | 1,333 mcg | 1.333 mg |
| 50 u | 0.50 mL | 1,667 mcg | 1.667 mg |
| 60 u | 0.60 mL | 2,000 mcg | 2 mg |
| 70 u | 0.70 mL | 2,333 mcg | 2.333 mg |
| 80 u | 0.80 mL | 2,667 mcg | 2.667 mg |
| 90 u | 0.90 mL | 3,000 mcg | 3 mg |
| 100 u | 1.00 mL | 3,333 mcg | 3.333 mg |
How the math works
- Concentration — divide the amount entered by the liquid volume used in the calculation: mg ÷ mL = mg/mL. This tells you how many mg are in each mL.
- Volume — the dose divided by that concentration: dose ÷ (mg/mL) = mL.
- Units — on a U-100 syringe one unit is 0.01 mL, so mL × 100 = units. A U-40 unit is 0.025 mL, so the wrong barrel is a 2.5× error. That is why the calculator asks which one you have.
- Rounding gap — the exact draw against the nearest syringe line: |exact − nearest line| ÷ exact × 100 = % difference.
Useful guides for this calculation
The math is only one part of the question. These guides cover the compound, published doses, side effects, mixing steps and supplies.