With 2 mL bacteriostatic water
20.0 units
Page last checked
Reconstitution · MOTS-c
MOTS-c dosage calculator
Pick the vial, the water you added and the dose. Get the exact draw in units for the syringe in your hand.
Step 1 of 4
- total mg in the calculation
- mL used in the calculation
- mg
This vial holds 10 mg in total.
- match the size on the package
U-100 insulin syringe · 1 mL · lines every 2 units · 1 unit = 0.01 mL
Draw to
30.0units
30.0 units on a U-100 insulin syringe · 1 mL · lines every 2 units, which is 0.30 milliliters. The draw lands on a syringe line.
10 mg ÷ 3 mL = 3.33 mg/mL
→ 33 mcg/unit · 1 mg = 0.300 mL = 30.0 units
→ 33 mcg/unit · 1 mg = 0.300 mL = 30.0 units
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How to use the calculator
- 1
Enter the amount in the vial
- 2
Enter the water you added
- 3
Enter the dose you want to convert
MOTS-c is a peptide sixteen amino acids long. What makes it unusual is where it is coded: inside mitochondrial DNA, not in the cell nucleus that codes for nearly everything else. It is sold for fat loss, exercise capacity and metabolic aging, on the observation that blood levels fall as people get older.
The metabolic results are mouse experiments, injected into the abdomen. Levels do fall with age in people. But falling with age is not the same as helping when topped up, and nobody has tested the second thing. No trial has published a dose for a person.
No completed controlled human trial has shown which dose works for MOTS-c. There is no study-backed human dosing program to publish. Animal quantities are not converted into a human recommendation.
no human dose shown to work
Examples using 10 mg of MOTS-c
Each row uses 10 mg and the liquid volume shown. Dividing the amount by that volume gives the calculated concentration. The rows are arithmetic examples, not alternative product preparations.
◆ How liquid volume changes the resultdose used: 1 mg
With 3 mL bacteriostatic water
30.0 units
| Bacteriostatic water | Concentration | Per U-100 unit | Draw for 1 mg | Nearest syringe line |
|---|---|---|---|---|
| 2 mL | 5.00 mg/mL | 50.0 mcg | 20.0 u · 0.200 mL | exactly 20 u |
| 3 mL | 3.33 mg/mL | 33.3 mcg | 30.0 u · 0.300 mL | exactly 30 u |
The amount, liquid volume and dose shown here are the calculator’s starting example for MOTS-c. Replace them with your own values. Every result in the table is calculated from those inputs.
MOTS-c: the calculator models an input, not an established dose
The MOTS-c guide does not identify an established human dose. The amount shown when the calculator opens is an example input. Its presence on the screen does not mean a study established it.
Open the mixing details3 notes
Measurements of a peptide are not replacement doses
Research can measure a substance already present in the body without testing whether giving more of it helps. An observed level, a change with age or a result in cells is not an amount for someone to take.
The same distinction applies to trial registrations. A registered plan describes intended research; it is not proof that treatment occurred or that results support a regimen. The guide is where the evidence status and source context belong.
What the calculation can establish
From the vial amount and liquid volume, the tool calculates a concentration. From that concentration and the requested amount, it calculates a draw. Each result depends on the inputs being an accurate description of the preparation being modeled.
The syringe type also matters. Its scale determines what the displayed units mean and which syringe line is nearest the target. The tool can expose a mismatch between those quantities without deciding whether the requested amount is appropriate.
A neat concentration does not validate the starting amount
Preset values make the arithmetic easier to explore. They do not establish product identity, preparation instructions or a MOTS-c treatment schedule. A neat result can be produced from an unsupported input just as easily as from a supported one.
Changing the water volume changes the concentration and the liquid required for the same amount. It does not create evidence for that amount. Keeping these questions separate prevents the precision of the output from overstating what is known.
The MOTS-c amounts in the cited experiments were animal doses
The cited mouse work used amounts based on body weight and a route into the abdominal cavity. Those experiments do not establish a human injection dose. The tool’s mass field cannot make that translation.
Read the supporting evidence3 supporting notes
Weight-based arithmetic does not bridge species
Multiplying a mouse dose by a person’s weight does not establish a human dose. A mouse and a person may handle the same compound differently. The route matters too. Both limits stay attached to the amount shown in the paper.
Measuring MOTS-c in blood is not testing a treatment
Observational measurements of the body’s own peptide ask a different question from giving it as a drug. A difference between groups does not identify a replacement amount or show that supplementation would improve an outcome.
The example vial is not a clinical protocol
The strength and water entered describe a math example. They do not identify a tested human product or verify what is in a vial. A clear numerical result does not fill the gap left by the missing dose evidence.
Weight-based arithmetic does not bridge species
Multiplying a mouse dose by a person’s weight does not establish a human dose. A mouse and a person may handle the same compound differently. The route matters too. Both limits stay attached to the amount shown in the paper.
Measuring MOTS-c in blood is not testing a treatment
Observational measurements of the body’s own peptide ask a different question from giving it as a drug. A difference between groups does not identify a replacement amount or show that supplementation would improve an outcome.
The example vial is not a clinical protocol
The strength and water entered describe a math example. They do not identify a tested human product or verify what is in a vial. A clear numerical result does not fill the gap left by the missing dose evidence.
Units to dose at 3.33 mg/mL
Mix 10 mg into 3 mL and one U-100 unit carries 33.3 mcg. The table shows how much peptide is in each numbered syringe line. These are conversion examples, not suggested doses.
Open the unit conversion table10 rows
| U-100 line | Volume | Mass (mcg) | Mass (mg) |
|---|---|---|---|
| 10 u | 0.10 mL | 333 mcg | 0.333 mg |
| 20 u | 0.20 mL | 667 mcg | 0.667 mg |
| 30 u | 0.30 mL | 1,000 mcg | 1 mg |
| 40 u | 0.40 mL | 1,333 mcg | 1.333 mg |
| 50 u | 0.50 mL | 1,667 mcg | 1.667 mg |
| 60 u | 0.60 mL | 2,000 mcg | 2 mg |
| 70 u | 0.70 mL | 2,333 mcg | 2.333 mg |
| 80 u | 0.80 mL | 2,667 mcg | 2.667 mg |
| 90 u | 0.90 mL | 3,000 mcg | 3 mg |
| 100 u | 1.00 mL | 3,333 mcg | 3.333 mg |
How the math works
- Concentration — divide the amount entered by the liquid volume used in the calculation: mg ÷ mL = mg/mL. This tells you how many mg are in each mL.
- Volume — the dose divided by that concentration: dose ÷ (mg/mL) = mL.
- Units — on a U-100 syringe one unit is 0.01 mL, so mL × 100 = units. A U-40 unit is 0.025 mL, so the wrong barrel is a 2.5× error. That is why the calculator asks which one you have.
- Rounding gap — the exact draw against the nearest syringe line: |exact − nearest line| ÷ exact × 100 = % difference.
Useful guides for this calculation
The math is only one part of the question. These guides cover the compound, published doses, side effects, mixing steps and supplies.