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Wegovy pill dosage chart: every strength and the schedule
The Wegovy tablet starts at 1.5 mg once a day and moves up every 30 days to 25 mg. Three strengths sit in between. Two other semaglutide tablets exist, and neither of them uses these numbers.
Source: Read from the Wegovy label, 2026-08-20
What matters first
Medically reviewed by Jennifer Montecillo, MD · non-practicing medical reviewerReviewed 2026-08-20every dose here is read off a label
The Wegovy tablet chart
Four strengths and three moves. Each strength runs 30 days, and only the last one is a dose the label says you stay on.
| When | Daily dose | Can you stay here? | What the label notes |
|---|---|---|---|
| Days 1 to 30 | 1.5 mg | No — a step only | Starting dosage |
| Days 31 to 60 | 4 mg | No — a step only | Escalation step only |
| Days 61 to 90 | 9 mg | No — a step only | Escalation step only |
| Day 91 and after | 25 mg | Yes | The one maintenance dosage the label names for the tablet |
So a full climb takes 90 days. The tablet reaches its settled dose on day 91, and the label names one settled dose rather than a choice of two. It covers heart-risk reduction and weight reduction in adults, and nothing else.
The label adds one line worth knowing before day 31. If a step is not handled well, it says to consider delaying the next one. Slowing down is inside the schedule, not a departure from it.
Every semaglutide tablet, side by side
Three products, one molecule, three different sets of numbers. The label that covers two of them opens by saying the milligrams do not carry across.
“RYBELSUS and OZEMPIC tablets are not substitutable on a mg-to-mg basis.”
| From | RybelsusNDA 213051 | Ozempic tabletsNDA 213051 | Wegovy tabletsNDA 218316 |
|---|---|---|---|
| Day 1 | 3 mga step only | 1.5 mga step only | 1.5 mga step only |
| Day 31 | 7 mgcan stay here | 4 mgcan stay here | 4 mga step only |
| Day 61 | 14 mgcan stay here | 9 mgcan stay here | 9 mga step only |
| Day 91 | — | — | 25 mgcan stay here |
| Approved for | Blood sugar in adults with type 2 diabetes | Blood sugar in adults with type 2 diabetes | Weight reduction in adults, and heart-risk reduction |
Read across a row and the pattern is the same while the numbers never are. All three move on day 31. All three move again on day 61. What changes is what is printed on the tablet.
The last row is why that matters. Two of these are for blood sugar and one is for weight, so a strength on one bottle is not a strength on another in any sense at all.
Both diabetes tablets also say something about their own first month that is easy to miss. The starting strength is not effective for blood sugar control, in the label’s own words. It is there to let the gut settle, not to treat anything.
How is the tablet taken?
Six rules, all of them on the label, and none of them optional. Together they are the thirty minutes a day a tablet asks for that a weekly injection does not.
One tablet a day, in the morning, before anything else.
Water only, and no more than four ounces of it.
Never two in a day, whatever happened yesterday.
Whole. Not halved, not crushed, not opened into a drink.
Then thirty minutes of nothing — no food, no coffee, no other pills.
A missed day is skipped, not caught up.
The quotes above are from the label covering Rybelsus and Ozempic tablets. The Wegovy label asks for the same thing in its own words, so all three tablets share these rules.
The thirty-minute wait is the part people trip on. It rules out coffee, juice and every other tablet in the morning routine, not just breakfast.
Is every GLP-1 tablet like this?
No. There is a second GLP-1 tablet now, it is not semaglutide, and it asks for no empty stomach and no thirty-minute wait at all.
Orforglipron, sold as Foundayo, was approved on 2026-04-01 for weight. Its label says to take it with or without food. The rules above belong to semaglutide tablets, not to tablets.
The two also disagree about a missed day. The label quoted above says to skip it. The other one says to take it as soon as you can. Nothing about either bottle tells you which rule is yours.
Its ladder is a different shape too: six strengths, thirty days apart, ending at a maximum rather than at a dose to settle on. The orforglipron dosage chart carries it with the label quotes.
Does a stronger tablet cost more?
No. Within each brand every strength costs a pharmacy the same, so the ladder is about tolerance rather than about money.
| Tablet | Strengths | Cheapest per tablet | Dearest per tablet | Gap |
|---|---|---|---|---|
| Ozempic | 1.5 mg, 4 mg | $33.07 | $33.09 | 0.08% |
| Rybelsus | 3 mg, 7 mg, 14 mg | $33.16 | $33.19 | 0.08% |
| Wegovy | 1.5 mg, 4 mg, 9 mg, 25 mg | $43.38 | $43.51 | 0.29% |
The widest gap in that table is 0.29 percent, on Wegovy. The Wegovy ladder carries 16.7 times as much drug at the top as at the bottom, and costs a pharmacy the same either way.
Two things follow. Climbing the ladder does not raise what the drug costs to buy. And splitting a tablet would save nothing even if the label allowed it, which it does not.
These are what pharmacies report paying to buy the drug, published weekly by CMS. No patient is offered them. What Wegovy pills cost, in full carries the offers, the exclusions and the Medicare route.
CMS National Average Drug Acquisition Cost, weekly file of 12 August 2026, read 13 August 2026 · the dataset · Centers for Medicare & Medicaid Services
Which strength swaps for which?
The label prints the swaps, and they are the only place a regulator says what one of these tablets is worth in another.
| From | To | Gap the label sets | What it attaches |
|---|---|---|---|
| Rybelsus 7 mg once daily | Ozempic tablets 4 mg once daily | Start the other product the day after stopping the first | Not during the first 30 days — the label rules out switching in the initiation phase |
| Rybelsus 14 mg once daily | Ozempic tablets 9 mg once daily | Start the other product the day after stopping the first | The swap runs both ways; the label prints it as one table |
| Ozempic injection 0.5 mg once weekly | Rybelsus 7 mg or 14 mg once daily | One week after the last injection | The label names only the 0.5 mg injection dose as a starting point for this swap |
| Ozempic injection 0.5 mg once weekly | Ozempic tablets 4 mg or 9 mg once daily | One week after the last injection | — |
| Wegovy injection 2.4 mg once weekly | Wegovy tablets 25 mg once daily | One week after the last injection | For heart-risk reduction or weight reduction in adults, which is all the tablet covers |
Read the first two rows together with the quote above. The same label that swaps 7 mg for 4 mg is the one saying the two are not substitutable milligram for milligram. Both are true, and the second is why the first has to be printed at all.
What this chart cannot tell you
Four things, and the second is the one that costs people money.
- This is the schedule a label prints, not a schedule for anyone in particular. A prescriber can slow an escalation down, and both labels say to consider exactly that when a step is not handled well.
- The strengths on the three tablets are not one scale. A milligram on Rybelsus, on an Ozempic tablet and on a Wegovy tablet are three different amounts of treatment, and the NDA 213051 label says so in its own first line.
- There is no oral tirzepatide. No Zepbound or Mounjaro tablet is approved or marketed, so no dose chart for one can exist.
- These are dose schedules, not weight-loss results. Use the results pages to see what each trial reported.
The injection ladder is a different document with different numbers. The Wegovy injection schedule runs in weeks rather than in 30-day blocks and stops in a different place.
- RYBELSUS and OZEMPIC (semaglutide) tablets — FDA-approved Prescribing Information (DailyMed SPL), NDA 213051, revised 01/2026retrieved 2026-08-20FDA label
- openFDA structured product labeling API — the NDA 213051 oral semaglutide label as JSON, brand_name [OZEMPIC, RYBELSUS], effective 2026-01-30retrieved 2026-08-20FDA label
- openFDA structured product labeling API — the NDA 218316 Wegovy label as JSON, injection and tablets in one document, effective 2026-06-18retrieved 2026-08-20FDA label