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Wegovy pill dosage chart: every strength and the schedule

The Wegovy tablet starts at 1.5 mg once a day and moves up every 30 days to 25 mg. Three strengths sit in between. Two other semaglutide tablets exist, and neither of them uses these numbers.

Source: Read from the Wegovy label, 2026-08-20

What matters first

Starting dose
1.5 mg once daily
Strengths
4
Dose changes
Every 30 days
Settled dose
25 mg once daily

Medically reviewed by Jennifer Montecillo, MD · non-practicing medical reviewerReviewed 2026-08-20every dose here is read off a label

The Wegovy tablet chart

Four strengths and three moves. Each strength runs 30 days, and only the last one is a dose the label says you stay on.

The Wegovy tablets dose schedule, read from the FDA label on 2026-08-20
WhenDaily doseCan you stay here?What the label notes
Days 1 to 301.5 mgNo — a step onlyStarting dosage
Days 31 to 604 mgNo — a step onlyEscalation step only
Days 61 to 909 mgNo — a step onlyEscalation step only
Day 91 and after25 mgYesThe one maintenance dosage the label names for the tablet

So a full climb takes 90 days. The tablet reaches its settled dose on day 91, and the label names one settled dose rather than a choice of two. It covers heart-risk reduction and weight reduction in adults, and nothing else.

The label adds one line worth knowing before day 31. If a step is not handled well, it says to consider delaying the next one. Slowing down is inside the schedule, not a departure from it.

Every semaglutide tablet, side by side

Three products, one molecule, three different sets of numbers. The label that covers two of them opens by saying the milligrams do not carry across.

RYBELSUS and OZEMPIC tablets are not substitutable on a mg-to-mg basis.

That sentence is the first bullet of the dosing section on the FDA label covering both Rybelsus and Ozempic tablets, and it is printed again further down.

The daily dose of each semaglutide tablet on the day each step of its schedule begins, read from the two FDA labels on 2026-08-20
FromRybelsusNDA 213051Ozempic tabletsNDA 213051Wegovy tabletsNDA 218316
Day 13 mga step only1.5 mga step only1.5 mga step only
Day 317 mgcan stay here4 mgcan stay here4 mga step only
Day 6114 mgcan stay here9 mgcan stay here9 mga step only
Day 9125 mgcan stay here
Approved forBlood sugar in adults with type 2 diabetesBlood sugar in adults with type 2 diabetesWeight reduction in adults, and heart-risk reduction

Read across a row and the pattern is the same while the numbers never are. All three move on day 31. All three move again on day 61. What changes is what is printed on the tablet.

The last row is why that matters. Two of these are for blood sugar and one is for weight, so a strength on one bottle is not a strength on another in any sense at all.

Both diabetes tablets also say something about their own first month that is easy to miss. The starting strength is not effective for blood sugar control, in the label’s own words. It is there to let the gut settle, not to treat anything.

Semaglutide is not on FDA’s shortage list, checked 14 August 2026. Novo Nordisk has told FDA it is stopping all three Rybelsus strengths, and the notice gives the reason in one line: they are being replaced by Ozempic tablets. That is in FDA’s shortage database, read 14 August 2026.

How is the tablet taken?

Six rules, all of them on the label, and none of them optional. Together they are the thirty minutes a day a tablet asks for that a weekly injection does not.

  • One tablet a day, in the morning, before anything else.

    Label: “Take one RYBELSUS or OZEMPIC tablet orally once daily on an empty stomach in the morning with water (up to 4 ounces of water).

  • Water only, and no more than four ounces of it.

    Label: “Do not take RYBELSUS or OZEMPIC tablets with other liquids besides water.

  • Never two in a day, whatever happened yesterday.

    Label: “Do not take more than one tablet per day.

  • Whole. Not halved, not crushed, not opened into a drink.

    Label: “Swallow tablets whole. Do not split, crush, chew or dissolve in any solution.

  • Then thirty minutes of nothing — no food, no coffee, no other pills.

    Label: “After taking RYBELSUS or OZEMPIC tablets, wait at least 30 minutes before eating food, drinking beverages or taking other oral medications.

  • A missed day is skipped, not caught up.

    Label: “If a dose is missed, skip the missed dose and take the next dose the following day.

The quotes above are from the label covering Rybelsus and Ozempic tablets. The Wegovy label asks for the same thing in its own words, so all three tablets share these rules.

Wegovy label: “Take WEGOVY tablets orally once-daily on an empty stomach in the morning with water (up to 4 ounces). Do not take with other liquids besides water. Swallow tablets whole. Do not split, crush, chew or dissolve. After taking WEGOVY tablet wait at least 30 minutes before eating food, drinking beverages or taking other oral medications.

The thirty-minute wait is the part people trip on. It rules out coffee, juice and every other tablet in the morning routine, not just breakfast.

Is every GLP-1 tablet like this?

No. There is a second GLP-1 tablet now, it is not semaglutide, and it asks for no empty stomach and no thirty-minute wait at all.

Orforglipron, sold as Foundayo, was approved on 2026-04-01 for weight. Its label says to take it with or without food. The rules above belong to semaglutide tablets, not to tablets.

The two also disagree about a missed day. The label quoted above says to skip it. The other one says to take it as soon as you can. Nothing about either bottle tells you which rule is yours.

Its ladder is a different shape too: six strengths, thirty days apart, ending at a maximum rather than at a dose to settle on. The orforglipron dosage chart carries it with the label quotes.

Does a stronger tablet cost more?

No. Within each brand every strength costs a pharmacy the same, so the ladder is about tolerance rather than about money.

What a pharmacy reports paying per tablet at the weakest and strongest strength of each semaglutide tablet, from the CMS weekly file of 12 August 2026
TabletStrengthsCheapest per tabletDearest per tabletGap
Ozempic1.5 mg, 4 mg$33.07$33.090.08%
Rybelsus3 mg, 7 mg, 14 mg$33.16$33.190.08%
Wegovy1.5 mg, 4 mg, 9 mg, 25 mg$43.38$43.510.29%

The widest gap in that table is 0.29 percent, on Wegovy. The Wegovy ladder carries 16.7 times as much drug at the top as at the bottom, and costs a pharmacy the same either way.

Two things follow. Climbing the ladder does not raise what the drug costs to buy. And splitting a tablet would save nothing even if the label allowed it, which it does not.

These are what pharmacies report paying to buy the drug, published weekly by CMS. No patient is offered them. What Wegovy pills cost, in full carries the offers, the exclusions and the Medicare route.

CMS National Average Drug Acquisition Cost, weekly file of 12 August 2026, read 13 August 2026 · the dataset · Centers for Medicare & Medicaid Services

Which strength swaps for which?

The label prints the swaps, and they are the only place a regulator says what one of these tablets is worth in another.

The switches between semaglutide tablets and from the injection to a tablet, as the FDA labels print them
FromToGap the label setsWhat it attaches
Rybelsus 7 mg once dailyOzempic tablets 4 mg once dailyStart the other product the day after stopping the firstNot during the first 30 days — the label rules out switching in the initiation phase
Rybelsus 14 mg once dailyOzempic tablets 9 mg once dailyStart the other product the day after stopping the firstThe swap runs both ways; the label prints it as one table
Ozempic injection 0.5 mg once weeklyRybelsus 7 mg or 14 mg once dailyOne week after the last injectionThe label names only the 0.5 mg injection dose as a starting point for this swap
Ozempic injection 0.5 mg once weeklyOzempic tablets 4 mg or 9 mg once dailyOne week after the last injection
Wegovy injection 2.4 mg once weeklyWegovy tablets 25 mg once dailyOne week after the last injectionFor heart-risk reduction or weight reduction in adults, which is all the tablet covers

Read the first two rows together with the quote above. The same label that swaps 7 mg for 4 mg is the one saying the two are not substitutable milligram for milligram. Both are true, and the second is why the first has to be printed at all.

Going the other way, from a tablet back to a shot, is on the page on choosing between the two forms, with what each one asks of you.

What this chart cannot tell you

Four things, and the second is the one that costs people money.

  • This is the schedule a label prints, not a schedule for anyone in particular. A prescriber can slow an escalation down, and both labels say to consider exactly that when a step is not handled well.
  • The strengths on the three tablets are not one scale. A milligram on Rybelsus, on an Ozempic tablet and on a Wegovy tablet are three different amounts of treatment, and the NDA 213051 label says so in its own first line.
  • There is no oral tirzepatide. No Zepbound or Mounjaro tablet is approved or marketed, so no dose chart for one can exist.
  • These are dose schedules, not weight-loss results. Use the results pages to see what each trial reported.

The injection ladder is a different document with different numbers. The Wegovy injection schedule runs in weeks rather than in 30-day blocks and stops in a different place.

3primary sources, each with the day we read it — open the documents used on this page