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Reconstitution · AOD-9604

AOD-9604 dosage calculator

Pick the vial, the water you added and the dose. Get the exact draw in units for the syringe in your hand.

Step 1 of 4

  1. How many mg are in your vial?
    Vial amounttotal mg in the calculation
  2. How many mL of water did you add?
  3. What dose do you want to convert?
  4. Which syringe are you using?
Draw to
60.0units

0.60 mL in the syringe · 5 calculated doses from this amount

60.0 units on a U-100 insulin syringe · 1 mL · lines every 2 units, which is 0.60 milliliters. The draw lands on a syringe line.

Easy to read on this syringe. The calculated volume matches the 60-unit line. No rounding is needed.

5 mg ÷ 3 mL = 1.67 mg/mL
→ 17 mcg/unit · 1 mg = 0.600 mL = 60.0 units

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Show the math and syringe details

Can this syringe show the result clearly?

Easy to read on this syringe. 60.0 u is exactly the 60-unit line on a U-100 — no rounding error at all.

Want an easier syringe number?

This setup is already easy to read. Changing the water between 0.5 and 3 mL would not put 1 mg closer to a line on this U-100 syringe.

Adding more water makes the mixture less concentrated, so the same dose uses more syringe units. It does not change how much peptide is in the vial.

This setup is in the address bar — every input is part of the link.

Educational math, not medical advice — dosing decisions belong to a licensed clinician. The available tabs also show supply calculations and any sourced schedule.

How to use the calculator

  1. 1

    Enter the amount in the vial

    Use the total mg printed on your AOD-9604 vial.

  2. 2

    Enter the water you added

    Use the amount of water added to that vial, in mL.

  3. 3

    Enter the dose you want to convert

    Choose mg or mcg, then match the result to your syringe.

AOD-9604 is the tail end of human growth hormone — residues 176 to 191, with one extra amino acid added on the front. It is sold for fat loss, on the idea that this fragment carries the hormone’s fat-mobilizing part and leaves the rest behind.

That idea was tested properly and it did not hold. An Australian company ran controlled human obesity trials, the larger ones did not separate it from placebo on weight, and development stopped there. The 10 mg group lost less than the 1 mg group, and the doses were swallowed rather than injected.

Examples using 5 mg of AOD-9604

Each row uses 5 mg and the liquid volume shown. Dividing the amount by that volume gives the calculated concentration. The rows are arithmetic examples, not alternative product preparations.

◆ How liquid volume changes the resultdose used: 1 mg

With 2 mL bacteriostatic water

40.0 units

Concentration
2.50 mg/mL
Each U-100 unit
25.0 mcg
Syringe volume
0.400 mL
Nearest line
Exactly 40 units

With 3 mL bacteriostatic water

60.0 units

Starting example
Concentration
1.67 mg/mL
Each U-100 unit
16.7 mcg
Syringe volume
0.600 mL
Nearest line
Exactly 60 units

The amount, liquid volume and dose shown here are the calculator’s starting example for AOD-9604. Replace them with your own values. Every result in the table is calculated from those inputs.

Drawn from once a week at 1 mg, a 5 mg vial yields 5 doses — about 5.0 weeks of supply. No storage limit is assigned to this example. Follow the dispensing label for the specific product.

AOD-9604: oral trial amounts and reported injections need separate labels

The AOD-9604 guide presents oral trial amounts alongside a separately labeled range of reported use. Those are different kinds of information. Converting an entered amount into a syringe volume does not make the oral findings apply to an injection.

Open the mixing details3 notes

Keep the route attached to each figure

The oral trial entries describe amounts taken by mouth. Their study context cannot be replaced with an injection route simply because the calculator accepts the same unit of mass. A milligram states an amount, not an equivalent effect across routes.

The reported use entry has its own evidence label. Read that label with the range rather than treating every number in the guide as a tested injection schedule. The calculator does not choose between those contexts.

A tested range is not an escalation plan

Different amounts in a study describe the groups researchers compared. Their order on a page does not prescribe a sequence for an individual, and the largest amount is not automatically a goal.

That matters here because the guide discusses trial outcomes as well as amounts. A conversion table can show what a larger input would mean in liquid volume. It cannot turn that larger input into evidence of a better result.

Simple arithmetic still needs the right starting point

The AOD-9604 calculator has one vial-strength preset and two water-volume presets. At the same entered amount, changing the water changes concentration and the size of the draw. It does not change the amount itself.

The opening example produces a substantial reading on the selected scale. That does not remove the need to check units, vial strength and rounding after any edit. A readable result shows where the calculated volume falls. It does not establish that the entered amount is appropriate.

AOD-9604’s oral trial summaries do not establish an injection schedule

AOD-9604 has amounts described in obesity-trial summaries and smaller amounts reported in injected use. Those sources describe different routes and different kinds of evidence. They should not be merged into one dose range.

Read the supporting evidence3 supporting notes

The weight-loss results did not rise with the dose

The review describes an early trial in which a higher dose produced less weight loss than a lower one. A later, larger trial did not find significant weight loss. These findings come from trial summaries; they do not establish a dose to aim for.

A swallowed amount cannot be converted into an equivalent shot

Changing units preserves the mass. It does not tell you how much reaches the body by a different route. The reported injection range still describes what people use, rather than the amount tested in the oral studies.

Vial strength and treatment evidence answer separate questions

Knowing the mass in a vial is enough to work out a dilution. It does not show that the contents cause weight loss, how often to inject them or how long a mixed AOD-9604 vial will keep.

Units to dose at 1.67 mg/mL

Mix 5 mg into 3 mL and one U-100 unit carries 16.7 mcg. The table shows how much peptide is in each numbered syringe line. These are conversion examples, not suggested doses.

Open the unit conversion table10 rows
Numbered U-100 syringe lines converted to volume and mass at 1.67 milligrams per milliliter.
U-100 lineVolumeMass (mcg)Mass (mg)
10 u0.10 mL167 mcg0.167 mg
20 u0.20 mL333 mcg0.333 mg
30 u0.30 mL500 mcg0.5 mg
40 u0.40 mL667 mcg0.667 mg
50 u0.50 mL833 mcg0.833 mg
60 u0.60 mL1,000 mcg1 mg
70 u0.70 mL1,167 mcg1.167 mg
80 u0.80 mL1,333 mcg1.333 mg
90 u0.90 mL1,500 mcg1.5 mg
100 u1.00 mL1,667 mcg1.667 mg

How the math works

  1. Concentration — divide the amount entered by the liquid volume used in the calculation: mg ÷ mL = mg/mL. This tells you how many mg are in each mL.
  2. Volume — the dose divided by that concentration: dose ÷ (mg/mL) = mL.
  3. Units — on a U-100 syringe one unit is 0.01 mL, so mL × 100 = units. A U-40 unit is 0.025 mL, so the wrong barrel is a 2.5× error. That is why the calculator asks which one you have.
  4. Rounding gap — the exact draw against the nearest syringe line: |exact − nearest line| ÷ exact × 100 = % difference.

Medically reviewed by Kenneth Montecillo, MD2026-09-07open the primary sources

Useful guides for this calculation

The math is only one part of the question. These guides cover the compound, published doses, side effects, mixing steps and supplies.

AOD-9604 without an approved label: what exists instead

No published half-life figure was found for AOD-9604.

AOD-9604 dosing evidence, without an approved schedule

2 published AOD-9604 dose values, each linked to the original source.

Which AOD-9604 reactions warrant medical attention

No boxed warning applies to AOD-9604, which reflects the review it has not had.

What the AOD-9604 draw needs from buying the mixing water

What a label allows, stated for buying the mixing water rather than for AOD-9604.

Bacteriostatic water before the AOD-9604 arithmetic starts

The added preservative, and what it allows, read off a federal page rather than off an AOD-9604 page.

Choosing the Hospira vial for an AOD-9604 draw

Which bacteriostatic water is the Hospira one? The answer holds for AOD-9604 as it does for anything else in a vial.

Questions readers ask

How much water to add to reconstitute peptides?

Whatever you add, the dose stays the same. Water sets the concentration, and the concentration sets how many marks on the barrel that dose covers.

For a 5 mg vial, adding 2 mL makes a 2.5 mg/mL solution, so 1 mg draws 40 units. Adding 3 mL makes a 1.67 mg/mL solution, so the same 1 mg draws 60 units.

How much AOD-9604 should I start with?

No trial can answer that, because the controlled human trials swallowed this fragment rather than injecting it. Those trials ran twelve weeks. The 1 mg group lost 2.6 kg against 0.8 kg on placebo, and the 10 mg group lost less than the 1 mg group did.

A 2026 review writes down what circulates instead: 250 to 500 micrograms a day, split over two or three injections. That is a report of practice, at roughly a tenth of the swallowed amount. The calculator turns a quantity you already hold into units, and picks nothing.

How to reconstitute AOD-9604 pdf?

There is no PDF, because there is no approved AOD-9604 product and no maker’s document behind one. Development stopped when the larger obesity trials failed to separate the fragment from placebo. Any mixing sheet circulating as a PDF came from a seller.

The arithmetic is short enough to need no document. Vial strength divided by water gives mg/mL, and one U-100 unit is a hundredth of a milliliter of that. So 5 mg in 3 mL puts 16.7 micrograms in every unit.

Should AOD-9604 be refrigerated?

No published source gives a storage period for mixed AOD-9604. The dispensing pharmacy should tell you how long a prepared vial stays usable.

AOD-9604 has no approved product label, so there is no official storage window to quote. The available labeled storage figures belong to approved injection pens, not this compound.

2primary sources, each with the day we read it — open the documents used on this page