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Reconstitution · NAD+

NAD+ dosage calculator

Pick the vial, the water you added and the dose. Get the exact draw in units for the syringe in your hand.

Step 1 of 4

  1. How many mg are in your vial?
    Vial amounttotal mg in the calculation
  2. How many mL of water did you add?
  3. What dose do you want to convert?
  4. Which syringe are you using?
Draw to
50.0units

0.50 mL in the syringe · 10 calculated doses from this amount

50.0 units on a U-100 insulin syringe · 1 mL · lines every 2 units, which is 0.50 milliliters. The draw lands on a syringe line.

Easy to read on this syringe. The calculated volume matches the 50-unit line. No rounding is needed.

500 mg ÷ 5 mL = 100.00 mg/mL
→ 1,000 mcg/unit · 50 mg = 0.500 mL = 50.0 units

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Show the math and syringe details

Can this syringe show the result clearly?

Easy to read on this syringe. 50.0 u is exactly the 50-unit line on a U-100 — no rounding error at all.

Want an easier syringe number?

This setup is already easy to read. Changing the water between 0.5 and 3 mL would not put 50 mg closer to a line on this U-100 syringe.

Adding more water makes the mixture less concentrated, so the same dose uses more syringe units. It does not change how much peptide is in the vial.

This setup is in the address bar — every input is part of the link.

Educational math, not medical advice — dosing decisions belong to a licensed clinician. The available tabs also show supply calculations and any sourced schedule.

How to use the calculator

  1. 1

    Enter the amount in the vial

    Use the total mg printed on your NAD+ vial.

  2. 2

    Enter the water you added

    Use the amount of water added to that vial, in mL.

  3. 3

    Enter the dose you want to convert

    Choose mg or mcg, then match the result to your syringe.

NAD+ is a substance every cell uses to turn food into energy and carry out repair work. It is a coenzyme, not a peptide. Clinics promote NAD+ IV drips and injections for energy, focus, recovery, hangovers, addiction recovery and healthy aging.

The human studies on NAD+ itself are small and used IV infusions. They have not shown that NAD+ injections improve those goals. The clearest finding so far is discomfort during the drip, including stomach symptoms, a faster heartbeat and chest pressure.

Examples using 500 mg of NAD+

Each row uses 500 mg and the liquid volume shown. Dividing the amount by that volume gives the calculated concentration. The rows are arithmetic examples, not alternative product preparations.

◆ How liquid volume changes the resultdose used: 50 mg

With 3 mL bacteriostatic water

30.0 units

Concentration
166.67 mg/mL
Each U-100 unit
1,666.7 mcg
Syringe volume
0.300 mL
Nearest line
Exactly 30 units

With 5 mL bacteriostatic water

50.0 units

Starting example
Concentration
100.00 mg/mL
Each U-100 unit
1,000.0 mcg
Syringe volume
0.500 mL
Nearest line
Exactly 50 units

The amount, liquid volume and dose shown here are the calculator’s starting example for NAD+. Replace them with your own values. Every result in the table is calculated from those inputs.

Drawn from once a week at 50 mg, a 500 mg vial yields 10 doses — about 10.0 weeks of supply. No storage limit is assigned to this example. Follow the dispensing label for the specific product.

NAD+: check the amount, volume and concentration as separate inputs

The NAD+ preset uses a large vial amount. The calculator still follows the same relationship: amount divided by modeled liquid volume gives concentration. It does not measure the preparation or determine its final volume.

Open the mixing details3 notes

What the volume field assumes

The worked calculation uses the entered water volume as the solution volume. That is a modeling assumption. The tool cannot measure any difference between liquid added and final prepared volume, or determine a correction from the powder’s appearance.

There is no measured displacement adjustment in this calculation. Where a preparation has a stated final concentration, that concentration is information about the actual preparation; a preset is only an example. A mismatch between them needs clarification rather than an invented correction.

Keep the mass unit visible

The NAD+ record uses amounts expressed in milligrams. A decimal or unit error changes the amount represented by a draw even when the displayed syringe reading looks familiar. The vial total is also different from the amount requested for one draw.

Read the conversion table’s amount and volume together. Syringe units are a way to read a particular scale, not a universal NAD+ dose. A remembered unit count loses its meaning when the concentration or syringe changes.

A registered infusion plan is not a completed finding

The guide includes registered intravenous study protocols. Registration records describe a plan and its status; they do not, on their own, establish completed results or a regimen for use under the skin.

The calculator does not translate an infusion protocol into an injection schedule. Its output describes the current inputs only. Evidence about route, preparation and outcomes needs to be read in the study context, separately from whether the liquid-volume arithmetic is correct.

NAD+ trial records describe different infusion protocols

The cited registered studies investigate different populations, amounts and treatment periods. A registered protocol records a plan; it is not, by itself, a published result or proof of a benefit from an infusion.

Read the supporting evidence3 supporting notes

NAD+ and its precursors are different substances

Nicotinamide riboside and nicotinamide mononucleotide are different molecules that the body can use to make NAD+. A study of either one does not automatically give a dose for direct NAD+ use. The exact substance and route still matter.

An infusion includes more than its total mass

An infusion protocol includes more than the mass of NAD+. It also describes the liquid used, the delivery time and the checks made during treatment. A result in syringe units cannot stand in for that full plan.

A larger vial does not choose a larger treatment

Vial strength is the amount available for the math. It does not tell you how much benefit to expect or which amount suits a person. Each trial’s dose remains attached to the question that study is asking.

Units to dose at 100.00 mg/mL

Mix 500 mg into 5 mL and one U-100 unit carries 1,000.0 mcg. The table shows how much peptide is in each numbered syringe line. These are conversion examples, not suggested doses.

Open the unit conversion table10 rows
Numbered U-100 syringe lines converted to volume and mass at 100.00 milligrams per milliliter.
U-100 lineVolumeMass (mcg)Mass (mg)
10 u0.10 mL10,000 mcg10 mg
20 u0.20 mL20,000 mcg20 mg
30 u0.30 mL30,000 mcg30 mg
40 u0.40 mL40,000 mcg40 mg
50 u0.50 mL50,000 mcg50 mg
60 u0.60 mL60,000 mcg60 mg
70 u0.70 mL70,000 mcg70 mg
80 u0.80 mL80,000 mcg80 mg
90 u0.90 mL90,000 mcg90 mg
100 u1.00 mL100,000 mcg100 mg

How the math works

  1. Concentration — divide the amount entered by the liquid volume used in the calculation: mg ÷ mL = mg/mL. This tells you how many mg are in each mL.
  2. Volume — the dose divided by that concentration: dose ÷ (mg/mL) = mL.
  3. Units — on a U-100 syringe one unit is 0.01 mL, so mL × 100 = units. A U-40 unit is 0.025 mL, so the wrong barrel is a 2.5× error. That is why the calculator asks which one you have.
  4. Rounding gap — the exact draw against the nearest syringe line: |exact − nearest line| ÷ exact × 100 = % difference.

Medically reviewed by Kenneth Montecillo, MD2026-09-07open the primary sources

Useful guides for this calculation

The math is only one part of the question. These guides cover the compound, published doses, side effects, mixing steps and supplies.

NAD+ without an approved label: what exists instead

No published half-life figure was found for NAD+.

The NAD+ reactions reported most often

Frequency bands exactly as the NAD+ source states them, with grouped figures kept grouped.

Choosing a water volume for a 500 mg NAD+ vial

How the water volume changes concentration, draw size and doses per 500 mg NAD+ vial.

What the NAD+ draw needs from the Zepbound vial draw

What a label allows, stated for the Zepbound vial draw rather than for NAD+.

The generic calculator behind the NAD+ one

Vial strength and water volume in and the exact mark out, with NAD+ as context

Choosing buying the mixing water for an NAD+ draw

Can anybody just buy bacteriostatic water? The answer holds for NAD+ as it does for anything else in a vial.

3primary sources, each with the day we read it — open the documents used on this page