Page last checked
Goal
Peptides for sexual function
FDA approves PT-141 as Vyleesi for a defined low-desire disorder in women before menopause. Kisspeptin-10 has small hormone studies, not a proven treatment for sexual function.
Source for this answer
Source: Based on 2 compound guides · checked 2026-09-07
Source: Based on 2 compound guides · checked 2026-09-07
The product, health condition and patient group matter. Vyleesi’s label does not cover men, women after menopause or use to enhance sexual performance.
Kisspeptin-10 studies measured hormone responses in healthy volunteers. Those results do not by themselves show improved desire, erections or fertility.
At a glance
Compounds covered
2
FDA-approved for this goal
1
Being tested for this goal
0
Reported use only
0
Two compounds, and who the evidence is about
Check who was studied, what they received and which outcome was measured. A hormone rise does not show that sex drive improved.
| Compound | What people take it for | What research shows | Evidence |
|---|---|---|---|
| PT-141Vyleesi | Sought for sexual desire or erections, as either the approved Vyleesi product or research powder.FDA-approved for this | FDA approves Vyleesi for a defined low-desire disorder in women before menopause. Its label does not cover men, women after menopause or better sexual performance. It gives 1.75 mg as needed, limits dosing to once in 24 hours, and advises against more than eight doses a month. | FDA labelDose from the FDA-approved label |
| Kisspeptin-10 | Sold for libido, for fertility and for raising testosterone, on its position upstream of the sex hormones.Measured in a human study | Small studies tracked sex hormones in healthy people. Responses differed by sex and menstrual cycle phase. In women studied during the follicular phase, doses into a vein or under the skin did not raise LH or FSH. They tested hormone effects, not whether sex drive improved. | limited human dataDose from a human trial · no FDA label |
What the Vyleesi approval covers
FDA approves Vyleesi for acquired, generalized hypoactive sexual desire disorder in women before menopause. The label defines additional limits on the diagnosis and says it is not approved for men or women after menopause.
The label also says it is not intended to enhance sexual performance. These limits describe the approved use; they are not a claim about who buys research products.
The approved product is a prefilled 1.75 mg autoinjector. A powder sold for mixing is not that formulation. In the approval trials, 18% of Vyleesi participants stopped because of side effects, compared with 2% on placebo.
Kisspeptin results depend on the study population
Kisspeptin-10 responses varied with sex and menstrual cycle phase. In women studied during the follicular phase, neither dosing into a vein nor under the skin raised the measured reproductive hormones.
These results do not isolate route as the reason for the different response in men. These small hormone studies do not set a dose to improve desire, erections or fertility.
Where to go next
Open the PT-141 reconstitution calculatorWhy no page here ranks anything
How PT-141 differs from the rest of its class
Kisspeptin-10 without an approved label: what exists instead
Which testosterone claims have a trial
The skin table, basis by basis
Where the anxiety and depression evidence stops
What is established for healing and recovery
Longevity: the page beside the pitch
- VYLEESI (bremelanotide) injection — FDA-approved Prescribing Information (DailyMed SPL)retrieved 2026-09-19FDA label
- Jayasena CN, Nijher GM, Comninos AN, et al. The effects of kisspeptin-10 on reproductive hormone release show sexual dimorphism in humans. J Clin Endocrinol Metab. 2011;96(12):E1963-72retrieved 2026-08-12limited human data
- George JT, Veldhuis JD, Roseweir AK, et al. Kisspeptin-10 is a potent stimulator of LH and increases pulse frequency in men. J Clin Endocrinol Metab. 2011;96(8):E1228-36retrieved 2026-08-12limited human data