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Peptides for testosterone

Four peptides on this site are sold for raising testosterone. Only one has ever been measured against it in a person, and that study ran a drip into a vein.

Source: Based on 4 compound guides · checked 2026-08-13

Testosterone itself is not a peptide and is not sold here. It is a steroid hormone, prescribed and controlled. None of the compounds below is testosterone, and none of them turns into it. What people buy under this heading are peptides they hope will move the hormone, which is a weaker claim than the heading suggests.

So each row states what people take a compound for, then what the published work measured. On three of the four rows nobody measured a sex hormone at all. This page is not advice about replacement therapy and does not weigh one against the other.

At a glance

Compounds covered

4

With published human dosing

3 of 4

Approved or being tested for this

0

No human evidence for this goal

3

Four compounds, and whether anyone measured the hormone

The left column reports what people take each one for. The right column is what the published work measured. Only the first row has a testosterone reading behind it, and that reading came out of an infusion given in a laboratory.

4 compounds coveredsources shown in each row
Compounds people take for this purpose, why they use them, what human research has measured, and where the evidence comes from.
CompoundWhat people take it forWhat research showsEvidence
Kisspeptin-10Bought by men to lift testosterone without a prescription, and sold for libido and fertility alongside that.Measured in a human studyThe human work is physiology research in groups of four to six people, run under ethics approval to map a hormone circuit rather than to treat anyone. A continuous infusion into a vein, for up to 22.5 hours, raised testosterone in healthy men. The largest dose ever given under the skin — the route these vials are sold for — moved neither gonadotropin in the women studied. FDA’s compounding advisory committee took the substance up in October 2024 for secondary hypogonadism in men, which is a review and not an approval.limited human dataDose from a human trial · no FDA label
SermorelinSold by wellness clinics for energy and body composition, and offered to men as a way around testosterone replacement or as something to run beside it.Reported use onlyNo study on this page measured testosterone. The largest trial ran in 110 children with growth-hormone deficiency. The one adult study ran 14 days in men of about 68, and only the 1 mg arm raised growth hormone above their own baseline. What circulates is 200 to 300 micrograms a day as a flat quantity — a fraction of the 0.5 to 1 mg twice daily that adult study gave.limited human dataDose from a human trial · no FDA label
TesamorelinEgrifta SV, Egrifta WRBought off-label for the growth-hormone effect of a genuinely approved medicine, and asked about as something that lifts testosterone.Reported use onlyIts label covers one thing: excess abdominal fat in adults with HIV-related lipodystrophy, at 1.4 mg once daily into the abdomen. That label states the drug is not indicated for weight loss, and rules it out where the hypothalamic-pituitary axis is disrupted. No testosterone endpoint appears anywhere on its record.FDA labelDose from the FDA-approved label
BPC-157Bought for tendon, muscle and gut complaints, and asked about both as a testosterone raiser and as something to run beside one.Reported use onlyNone of the published work measures testosterone or reproductive hormones. Nearly all research is in rats and mice. The human evidence is three uncontrolled pilot reports with fewer than 30 people in total, and none used an injection under the skin. A review describes the circulating 200–500 microgram daily range as informal scaling from rodent work.no human dose shown to workDose reported in the literature only

1 rests on a human study that measured something in this goal. 3 rest on reported use alone, with no study behind them.

The one testosterone reading here came out of a drip

Kisspeptin-10 is the only compound on this site that a study ever measured testosterone in. The study was not treatment. Researchers ran a continuous infusion into a vein for up to 22.5 hours in healthy men, pushing the top of the reproductive circuit to watch what it did. Testosterone rose. Nobody was treated and no quantity was set for anyone.

The route is the whole story here. Given under the skin, the way these vials are sold, the largest published dose moved neither gonadotropin in the women studied. An infusion in a laboratory and a syringe at home are not the same event. The groups were four to six people, and every dose was scaled per kilogram of body weight.

One regulatory thread runs through it, and it is worth reading precisely. FDA placed kisspeptin-10 in category 2 of its interim compounding policy in September 2023. Its advisory committee then took the substance up in October 2024, for secondary hypogonadism in men. A review is not an approval, and no company has filed to market it since.

Almost no record on this site mentions the hormone at all

Of every compound guide here, exactly one mentions testosterone. The growth-hormone peptides sold beside it act on a different output of the same gland, and no study on any of their records measured a sex hormone in either direction.

People ask it both ways — whether these lift testosterone and whether they suppress it — and the published research answers neither. Settling either question takes a hormone panel run over months against a control group. Nothing on these four pages is that.

No study set a quantity for raising testosterone with any of them. What circulates instead is practice: 200 to 300 micrograms a day of sermorelin, 200 to 500 of BPC-157, both flat numbers standing on animal work or habit. The kisspeptin quantities that did move the hormone were per kilogram of body weight, given by drip, under ethics approval.

Where to go next

Every purpose covered this way is listed on the index of goals people buy peptides for.

Questions readers ask

Does CJC Ipamorelin affect testosterone?

Nobody has measured testosterone after using the pair. CJC-1295 studies tracked growth hormone and IGF-I. Ipamorelin studies tracked growth hormone or gut recovery after surgery.

Does TB500 affect testosterone?

Nobody has measured it. FDA found no human exposure data for the fragment sold as TB-500. That leaves no person in whom testosterone was checked.

Does CJC-1295 suppress testosterone?

There is no evidence either way. Its two human studies measured growth hormone and IGF-I, not sex hormones. Both studies also lasted seven weeks or less.

Does CJC-1295 Ipamorelin decrease testosterone?

No study answers that question. The pair has no human trial on this site, and the separate records contain no testosterone result.

Does CJC affect testosterone?

Nobody looked. The CJC-1295 trials measured growth hormone, IGF-I and side effects. A hormone left off the study is unknown, not unchanged.

Are peptides better than testosterone?

The evidence cannot support that comparison. Testosterone is a steroid hormone, and none of these peptides becomes it. Only kisspeptin-10 was measured against testosterone at all.

Is it better to take peptides or testosterone?

No study on these sources compares those choices. Testosterone is prescribed as a hormone. The peptides here have different targets, and most have no testosterone result.

Does IGF-1 increase testosterone?

IGF-1 LR3 has never been studied in people, so no testosterone result exists. Its published work is animal and manufacturing research.

How much can kisspeptin raise testosterone?

No reliable amount can be given. Testosterone rose during a continuous vein infusion in healthy men, but each study group included only four to six people.

Will kisspeptin raise testosterone?

It did in one small study during a continuous infusion into a vein. Nothing shows that an injection under the skin does the same.

8primary sources, each with the day we read it — open the documents used on this page