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Goal
Peptides for testosterone
Four peptides on this site are sold for raising testosterone. Only one has ever been measured against it in a person, and that study ran a drip into a vein.
Source: Based on 4 compound guides · checked 2026-08-13
Testosterone itself is not a peptide and is not sold here. It is a steroid hormone, prescribed and controlled. None of the compounds below is testosterone, and none of them turns into it. What people buy under this heading are peptides they hope will move the hormone, which is a weaker claim than the heading suggests.
So each row states what people take a compound for, then what the published work measured. On three of the four rows nobody measured a sex hormone at all. This page is not advice about replacement therapy and does not weigh one against the other.
At a glance
Compounds covered
4
With published human dosing
3 of 4
Approved or being tested for this
0
No human evidence for this goal
3
Four compounds, and whether anyone measured the hormone
The left column reports what people take each one for. The right column is what the published work measured. Only the first row has a testosterone reading behind it, and that reading came out of an infusion given in a laboratory.
| Compound | What people take it for | What research shows | Evidence |
|---|---|---|---|
| Kisspeptin-10 | Bought by men to lift testosterone without a prescription, and sold for libido and fertility alongside that.Measured in a human study | The human work is physiology research in groups of four to six people, run under ethics approval to map a hormone circuit rather than to treat anyone. A continuous infusion into a vein, for up to 22.5 hours, raised testosterone in healthy men. The largest dose ever given under the skin — the route these vials are sold for — moved neither gonadotropin in the women studied. FDA’s compounding advisory committee took the substance up in October 2024 for secondary hypogonadism in men, which is a review and not an approval. | limited human dataDose from a human trial · no FDA label |
| Sermorelin | Sold by wellness clinics for energy and body composition, and offered to men as a way around testosterone replacement or as something to run beside it.Reported use only | No study on this page measured testosterone. The largest trial ran in 110 children with growth-hormone deficiency. The one adult study ran 14 days in men of about 68, and only the 1 mg arm raised growth hormone above their own baseline. What circulates is 200 to 300 micrograms a day as a flat quantity — a fraction of the 0.5 to 1 mg twice daily that adult study gave. | limited human dataDose from a human trial · no FDA label |
| TesamorelinEgrifta SV, Egrifta WR | Bought off-label for the growth-hormone effect of a genuinely approved medicine, and asked about as something that lifts testosterone.Reported use only | Its label covers one thing: excess abdominal fat in adults with HIV-related lipodystrophy, at 1.4 mg once daily into the abdomen. That label states the drug is not indicated for weight loss, and rules it out where the hypothalamic-pituitary axis is disrupted. No testosterone endpoint appears anywhere on its record. | FDA labelDose from the FDA-approved label |
| BPC-157 | Bought for tendon, muscle and gut complaints, and asked about both as a testosterone raiser and as something to run beside one.Reported use only | None of the published work measures testosterone or reproductive hormones. Nearly all research is in rats and mice. The human evidence is three uncontrolled pilot reports with fewer than 30 people in total, and none used an injection under the skin. A review describes the circulating 200–500 microgram daily range as informal scaling from rodent work. | no human dose shown to workDose reported in the literature only |
The one testosterone reading here came out of a drip
Kisspeptin-10 is the only compound on this site that a study ever measured testosterone in. The study was not treatment. Researchers ran a continuous infusion into a vein for up to 22.5 hours in healthy men, pushing the top of the reproductive circuit to watch what it did. Testosterone rose. Nobody was treated and no quantity was set for anyone.
The route is the whole story here. Given under the skin, the way these vials are sold, the largest published dose moved neither gonadotropin in the women studied. An infusion in a laboratory and a syringe at home are not the same event. The groups were four to six people, and every dose was scaled per kilogram of body weight.
One regulatory thread runs through it, and it is worth reading precisely. FDA placed kisspeptin-10 in category 2 of its interim compounding policy in September 2023. Its advisory committee then took the substance up in October 2024, for secondary hypogonadism in men. A review is not an approval, and no company has filed to market it since.
Almost no record on this site mentions the hormone at all
Of every compound guide here, exactly one mentions testosterone. The growth-hormone peptides sold beside it act on a different output of the same gland, and no study on any of their records measured a sex hormone in either direction.
People ask it both ways — whether these lift testosterone and whether they suppress it — and the published research answers neither. Settling either question takes a hormone panel run over months against a control group. Nothing on these four pages is that.
No study set a quantity for raising testosterone with any of them. What circulates instead is practice: 200 to 300 micrograms a day of sermorelin, 200 to 500 of BPC-157, both flat numbers standing on animal work or habit. The kisspeptin quantities that did move the hormone were per kilogram of body weight, given by drip, under ethics approval.
Where to go next
Where reported use ends and evidence starts
Every compound sold for skin
Which weight loss claims have a trial
How Kisspeptin-10 differs from the rest of its class
BPC-157 research, dosing, and approval status
How sermorelin differs from the rest of its class
The molecule behind Egrifta SV and Egrifta WR
Where the sleep evidence stops
Questions readers ask
Does CJC Ipamorelin affect testosterone?
Does TB500 affect testosterone?
Does CJC-1295 suppress testosterone?
Does CJC-1295 Ipamorelin decrease testosterone?
Does CJC affect testosterone?
Are peptides better than testosterone?
Is it better to take peptides or testosterone?
Does IGF-1 increase testosterone?
How much can kisspeptin raise testosterone?
Will kisspeptin raise testosterone?
- Mateescu DM, Gavrilescu DM, Constantinescu FE, Oancea C, Ilie AC, Folescu R, Popa MD, Iurciuc S, Muresan CO, Enache A. BPC-157 as an Investigational Peptide Therapeutic: Biopharmaceutical Challenges, Formulation Strategies, and Translational Development Barriers. Pharmaceutics 2026;18(5):625 — states the quantity used off-label and that it was extrapolated informally from rodent data, with no human pharmacokinetic or safety anchorretrieved 2026-08-13indirect evidence
- EGRIFTA SV (tesamorelin) for injection — FDA-approved Prescribing Information (DailyMed SPL)retrieved 2026-08-12FDA label
- Thorner M, et al. Once daily subcutaneous growth hormone-releasing hormone therapy accelerates growth in growth hormone-deficient children during the first year of therapy (Geref International Study Group). J Clin Endocrinol Metab 1996;81(3):1189-96retrieved 2026-08-12Human trial
- Corpas E, Harman SM, Piñeyro MA, Roberson R, Blackman MR. Growth hormone (GH)-releasing hormone-(1-29) twice daily reverses the decreased GH and insulin-like growth factor-I levels in old men. J Clin Endocrinol Metab 1992;75(2):530-5retrieved 2026-08-12Human trial
- NCT00324064 — Sexually Dimorphic Effects of GHRH in Adult Growth Hormone Testing (protocol: GHRH [Geref] 1 mcg/kg intravenous push, followed by arginine)retrieved 2026-08-12Human trial
- Dominikowski A, Rękoś Z, Olejarz M, Szczepanek-Parulska E, Domin R, Ruchała M. The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration. Front Endocrinol 2026 — tabulates self-reported online dosing patterns beside the clinical doses, stating the reported values must not be read as clinically validated, regulatory-approved or saferetrieved 2026-08-12indirect evidence
- Jayasena CN, Nijher GM, Comninos AN, et al. The effects of kisspeptin-10 on reproductive hormone release show sexual dimorphism in humans. J Clin Endocrinol Metab. 2011;96(12):E1963-72retrieved 2026-08-12limited human data
- George JT, Veldhuis JD, Roseweir AK, et al. Kisspeptin-10 is a potent stimulator of LH and increases pulse frequency in men. J Clin Endocrinol Metab. 2011;96(8):E1228-36retrieved 2026-08-12limited human data