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Reconstitution · DSIP

DSIP reconstitution calculator

Pick the vial, the water you added and the dose. Get the exact draw in units for the syringe in your hand.

Step 1 of 4

  1. How many mg are in your vial?
    Vial amounttotal mg in the calculation
  2. How many mL of water did you add?
  3. What dose do you want to convert?
  4. Which syringe are you using?
Draw to
7.5units

0.08 mL in the syringe · 40 calculated doses from this amount

7.5 units on a U-100 insulin syringe · 1 mL · lines every 2 units, which is 0.08 milliliters. The nearest syringe line is 8 units.

This falls between two syringe lines. The nearest line on this U-100 syringe is 8 units. Open the syringe details below to see the difference.

10 mg ÷ 3 mL = 3.33 mg/mL
→ 33 mcg/unit · 250 mcg = 0.075 mL = 7.5 units

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Show the math and syringe details

Can this syringe show the result clearly?

This draw falls between syringe lines. The exact volume is 7.50 units, but a U-100 syringe has a line every 2 units. Using the nearest line gives 8 units — a 6.7% difference, or 17 mcg.

Want an easier syringe number?

  • 2.5 mL of water instead4.00 mg/mL · 40 mcg/unit6.3 u4.0% off

Adding more water makes the mixture less concentrated, so the same dose uses more syringe units. It does not change how much peptide is in the vial.

This setup is in the address bar — every input is part of the link.

Educational math, not medical advice — dosing decisions belong to a licensed clinician. The available tabs also show supply calculations and any sourced schedule.

How to use the calculator

  1. 1

    Enter the amount in the vial

    Use the total mg printed on your DSIP vial.

  2. 2

    Enter the water you added

    Use the amount of water added to that vial, in mL.

  3. 3

    Enter the dose you want to convert

    Choose mg or mcg, then match the result to your syringe.

DSIP stands for delta sleep-inducing peptide. It is nine amino acids long, and it was recovered in 1977 from the blood of rabbits put into deep sleep electrically. It is sold for insomnia and for deeper sleep.

It has more human research than many peptides sold this way, but the evidence is still thin. European groups gave it during the 1980s to people with insomnia and to people in alcohol and opiate withdrawal, and reported improved sleep. The studies were small, mostly open label, used intravenous dosing and never led to an approval.

Examples using 10 mg of DSIP

Each row uses 10 mg and the liquid volume shown. Dividing the amount by that volume gives the calculated concentration. The rows are arithmetic examples, not alternative product preparations.

◆ How liquid volume changes the resultdose used: 250 mcg

With 2 mL bacteriostatic water

5.0 units

Concentration
5.00 mg/mL
Each U-100 unit
50.0 mcg
Syringe volume
0.050 mL
Nearest line
6 units · 20.0% off

With 3 mL bacteriostatic water

7.5 units

Starting example
Concentration
3.33 mg/mL
Each U-100 unit
33.3 mcg
Syringe volume
0.075 mL
Nearest line
8 units · 6.7% off

The amount, liquid volume and dose shown here are the calculator’s starting example for DSIP. Replace them with your own values. Every result in the table is calculated from those inputs.

Drawn from once a week at 250 mcg, a 10 mg vial yields 40 doses — about 40.0 weeks of supply. No storage limit is assigned to this example. Follow the dispensing label for the specific product.

DSIP: a different vial strength changes the syringe reading

The DSIP calculator offers two vial strengths, one twice the other. At the same water volume, the stronger vial has twice the concentration. The same entered amount therefore takes half as much liquid from that stronger setup.

Open the mixing details3 notes

A saved unit count needs its concentration

A syringe reading belongs to a particular vial amount and liquid volume. Changing either input can change what the same marked reading represents. The compound name alone is not enough to reconstruct the calculation.

The two vial presets make this easy to see, but water volume matters too. Neither input can be omitted when comparing readings. The calculator shows their combined effect rather than treating one as the only important choice.

Study amounts retain their weight and route terms

The DSIP sleep studies listed in the guide used intravenous amounts expressed per kilogram of body weight. That is different from a flat total amount entered for a draw. Removing the weight term changes the quantity being described.

Their findings also belong to their study populations and schedules. A syringe calculator cannot establish an equivalent regimen under the skin or turn a sleep-study result into a personal treatment plan. The guide keeps those source contexts available.

Small draws make rounding worth reading

The starting DSIP examples sit in the lower part of the syringe scale. The tool distinguishes the target volume from the nearest syringe line so the difference is not hidden by a tidy unit count.

That precision still depends on the inputs. The software cannot verify the material in a vial, measure its strength or confirm preparation instructions. If the amount or concentration is uncertain, the displayed result inherits that uncertainty even when the arithmetic is internally consistent.

DSIP’s original units include a body-weight factor

The cited sleep studies reported nanomoles per kilogram. The mass conversion retains that weight basis. Changing nanomoles to micrograms is one step; it does not turn the result into a flat dose per draw.

Read the supporting evidence2 supporting notes

Molecular weight explains the unit conversion

Nanomoles count molecules, while micrograms measure mass. The conversion uses the peptide’s molecular weight. The original amount and units remain beside the converted value so that the arithmetic can be checked.

The study schedule stays separate from the syringe result

The records include a single-dose account and a repeated intravenous course in a sleep laboratory. A general tool cannot choose between them, change the route or establish a suitable amount for a person. The studies also do not provide storage instructions for an unrelated mixed vial.

Units to dose at 3.33 mg/mL

Mix 10 mg into 3 mL and one U-100 unit carries 33.3 mcg. The table shows how much peptide is in each numbered syringe line. These are conversion examples, not suggested doses.

Open the unit conversion table10 rows
Numbered U-100 syringe lines converted to volume and mass at 3.33 milligrams per milliliter.
U-100 lineVolumeMass (mcg)Mass (mg)
10 u0.10 mL333 mcg0.333 mg
20 u0.20 mL667 mcg0.667 mg
30 u0.30 mL1,000 mcg1 mg
40 u0.40 mL1,333 mcg1.333 mg
50 u0.50 mL1,667 mcg1.667 mg
60 u0.60 mL2,000 mcg2 mg
70 u0.70 mL2,333 mcg2.333 mg
80 u0.80 mL2,667 mcg2.667 mg
90 u0.90 mL3,000 mcg3 mg
100 u1.00 mL3,333 mcg3.333 mg

How the math works

  1. Concentration — divide the amount entered by the liquid volume used in the calculation: mg ÷ mL = mg/mL. This tells you how many mg are in each mL.
  2. Volume — the dose divided by that concentration: dose ÷ (mg/mL) = mL.
  3. Units — on a U-100 syringe one unit is 0.01 mL, so mL × 100 = units. A U-40 unit is 0.025 mL, so the wrong barrel is a 2.5× error. That is why the calculator asks which one you have.
  4. Rounding gap — the exact draw against the nearest syringe line: |exact − nearest line| ÷ exact × 100 = % difference.

Medically reviewed by Kenneth Montecillo, MD2026-09-07open the primary sources

Useful guides for this calculation

The math is only one part of the question. These guides cover the compound, published doses, side effects, mixing steps and supplies.

2primary sources, each with the day we read it — open the documents used on this page