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Reconstitution · Kisspeptin-10
Pick the vial, the water you added and the dose. Get the exact draw in units for the syringe in your hand.
Step 1 of 4
This vial holds 10,000 mcg in total.
U-100 insulin syringe · 1 mL · lines every 2 units · 1 unit = 0.01 mL
4.5 units on a U-100 insulin syringe · 1 mL · lines every 2 units, which is 0.05 milliliters. The nearest syringe line is 4 units.
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Kisspeptin-10 is the ten-amino-acid working core of kisspeptin, the signal sitting at the very top of the reproductive hormone chain. It is sold for libido, for fertility, and for raising testosterone.
The human work is physiology research in groups of four to six people, run to map the circuit rather than to treat anyone. Given into a vein it lifted luteinising hormone in men within half an hour. Given under the skin — the route these vials are sold for — it moved neither hormone in the women studied.
Each row starts with the same 10 mg vial and changes only the amount of water. More water makes the mixture less concentrated, so the same dose uses more syringe units.
| Water added | Concentration | Per U-100 unit | Draw for 150 mcg | Nearest syringe line |
|---|---|---|---|---|
| 2 mL | 5.00 mg/mL | 50.0 mcg | 3.0 u · 0.030 mL | 4 u · 33.3% off |
| 3 mL | 3.33 mg/mL | 33.3 mcg | 4.5 u · 0.045 mL | 4 u · 11.1% off |
The vial, water and dose shown here are the calculator’s starting example for Kisspeptin-10. Replace them with your own values. Every result in the table is calculated from those inputs.
Kisspeptin-10’s responses in people came from injections into a vein. Under the skin, the largest amount studied moved neither hormone being measured. That belongs at the top of this page, not in a footnote.
In the study on record, a subcutaneous dose at the top of the range tested shifted neither of the two hormones the researchers tracked. The women in it were sampled at one point in the cycle.
The intravenous work is where the responses are. This page converts a dose into a subcutaneous draw because that is what the vial is for. The conversion is arithmetic. It is not evidence that the route does anything.
In the dose-ranging arm, the higher intravenous amount produced a smaller hormone response than the lower one did.
Whatever shape that curve has, it is not a rising line. A bigger draw is not a stronger version of a smaller one. The instinct that more signal gives more response is the wrong instinct here.
The conventional amount is a few hundred micrograms at most. It lands in single figures of units on most of this page’s combinations.
The larger vial makes that worse rather than better, because it packs more powder into the same water. The small vial with the larger water volume is the only pairing here that puts the draw where a syringe line can confirm it.
Kisspeptin-10 has more human dosing behind it than most of this group. None of it converts cleanly. All three rows on the page are per kilogram, and one of them is not a dose at all. It is an amount per kilogram per hour, delivered by infusion.
A dose is a mass. A rate is a mass spread across time, and it needs a duration and a pump before it becomes anything else. The infusion behind that row ran for the better part of a day.
One study published micrograms per kilogram, and the page uses those figures exactly as printed. The other published nanomoles per kilogram. Those were converted to mass at the peptide’s molecular weight, with the original printed beside the result.
The human work was investigator-run physiology. It was carried out under ethics approval, on pharmaceutical-grade material prepared for the protocol. No pharmacy dispenses this peptide, and no product exists to copy a strength from.
The agency placed this substance in the second category of its interim compounding policy. Two of the concerns it listed are about the material rather than the effect. That is unusual, and worth reading on a calculator page.
Mix 10 mg into 3 mL and one U-100 unit carries 33.3 mcg. The table shows how much peptide is in each numbered syringe line. These are conversion examples, not suggested doses.
| U-100 line | Volume | Mass (mcg) | Mass (mg) |
|---|---|---|---|
| 10 u | 0.10 mL | 333 mcg | 0.333 mg |
| 20 u | 0.20 mL | 667 mcg | 0.667 mg |
| 30 u | 0.30 mL | 1,000 mcg | 1 mg |
| 40 u | 0.40 mL | 1,333 mcg | 1.333 mg |
| 50 u | 0.50 mL | 1,667 mcg | 1.667 mg |
| 60 u | 0.60 mL | 2,000 mcg | 2 mg |
| 70 u | 0.70 mL | 2,333 mcg | 2.333 mg |
| 80 u | 0.80 mL | 2,667 mcg | 2.667 mg |
| 90 u | 0.90 mL | 3,000 mcg | 3 mg |
| 100 u | 1.00 mL | 3,333 mcg | 3.333 mg |
The math is only one part of the question. These guides cover the compound, published doses, side effects, mixing steps and supplies.
How strong the evidence is for Kisspeptin-10
What an empty Kisspeptin-10 safety page does and does not mean
The 10 mg Kisspeptin-10 vial: concentrations and example draws
Choosing a water volume for a 5 mg Kisspeptin-10 vial
What the Kisspeptin-10 draw needs from the two waters
The syringe scale for a Kisspeptin-10 vial