With 1 mL bacteriostatic water
4.0 units
Page last checked
Reconstitution · LL-37
LL-37 reconstitution calculator
Pick the vial, the water you added and the dose. Get the exact draw in units for the syringe in your hand.
Step 1 of 4
- total mg in the calculation
- mL used in the calculation
- mcg
This vial holds 5,000 mcg in total.
- match the size on the package
U-100 insulin syringe · 1 mL · lines every 2 units · 1 unit = 0.01 mL
Draw to
8.0units
8.0 units on a U-100 insulin syringe · 1 mL · lines every 2 units, which is 0.08 milliliters. The draw lands on a syringe line.
5 mg ÷ 2 mL = 2.50 mg/mL
→ 25 mcg/unit · 200 mcg = 0.080 mL = 8.0 units
→ 25 mcg/unit · 200 mcg = 0.080 mL = 8.0 units
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Show the math and syringe details
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How to use the calculator
- 1
Enter the amount in the vial
- 2
Enter the water you added
- 3
Enter the dose you want to convert
LL-37 is a peptide 37 amino acids long that your own white blood cells make. It kills bacteria by breaking open their outer membrane. It is sold for stubborn infections, for biofilms, and for gut complaints.
It has reached people twice in registered work: injected into melanoma deposits, and applied to venous leg ulcers. Neither study tested an infection. On the ulcers the two lower strengths improved healing while the highest did no better than placebo. The FDA cited animal findings of harm to male reproduction, and of tumor-promoting activity in some tissues.
Examples using 5 mg of LL-37
Each row uses 5 mg and the liquid volume shown. Dividing the amount by that volume gives the calculated concentration. The rows are arithmetic examples, not alternative product preparations.
◆ How liquid volume changes the resultdose used: 200 mcg
With 2 mL bacteriostatic water
8.0 units
With 3 mL bacteriostatic water
12.0 units
| Bacteriostatic water | Concentration | Per U-100 unit | Draw for 200 mcg | Nearest syringe line |
|---|---|---|---|---|
| 1 mL | 5.00 mg/mL | 50.0 mcg | 4.0 u · 0.040 mL | exactly 4 u |
| 2 mL | 2.50 mg/mL | 25.0 mcg | 8.0 u · 0.080 mL | exactly 8 u |
| 3 mL | 1.67 mg/mL | 16.7 mcg | 12.0 u · 0.120 mL | exactly 12 u |
The amount, liquid volume and dose shown here are the calculator’s starting example for LL-37. Replace them with your own values. Every result in the table is calculated from those inputs.
LL-37: a tumor-injection record is not a general injection regimen
The LL-37 guide describes a registered melanoma study using injections into tumor deposits. That route and purpose are part of the record. They cannot be replaced with a general injection schedule by converting the amount into syringe units.
Open the mixing details3 notes
Keep registration, treatment and results distinct
A registry can contain a planned enrollment, treatment details and posted results. Those fields answer different questions. An enrollment figure alone is not a count of people who received a particular amount or completed a course.
The linked guide holds the dated study record and its limitations. The calculator does not infer a broader evidence base from that record or identify which parts apply to another use. It only converts the amount currently entered.
Topical findings do not set a syringe dose
The guide also discusses LL-37 research on leg ulcers. A preparation applied to a wound is different from an injection into a tumor, and neither establishes a general amount to inject under the skin.
Study strengths and their outcomes must be read within each protocol. They are not a universal ranking of better and worse doses. Increasing a calculator input shows a larger liquid volume at the same concentration, not a predicted improvement in an outcome.
The volume presets illustrate the concentration change
This page uses one vial-strength preset and three water-volume presets. With the same amount entered, a larger water volume gives a lower concentration and a larger draw. The amount represented by that draw does not change.
The syringe output shows the target and any rounding difference for the selected scale. Those details help explain the calculation without selecting a mixing method. A readable mark cannot supply evidence for a route or purpose absent from the source being discussed.
The LL-37 melanoma trial used an amount per tumor
The registered trial described injections into individual melanoma tumors. Its quantity was stated per tumor, not as a routine whole-body dose. That distinction is essential when reading the amount beside a general syringe tool.
Read the supporting evidence3 supporting notes
A tumor count is not a calculator input
The total amount could depend on the tumors treated. The tool takes a single mass for a draw. It does not select treatment sites or reproduce the trial’s clinical decisions.
Tested levels are not a recommended range
The small trial explored dose levels in a specific cancer setting. Listing what was given does not establish a general LL-37 schedule for infections, immunity or wellness. The source context stays attached to the numbers.
A weekly protocol does not establish mixed-vial storage
Timing in a trial describes when treatment was given. It is not a shelf-life study for a separately prepared vial. A calculated supply of several draws does not show that the vial can be kept between them.
A tumor count is not a calculator input
The total amount could depend on the tumors treated. The tool takes a single mass for a draw. It does not select treatment sites or reproduce the trial’s clinical decisions.
Tested levels are not a recommended range
The small trial explored dose levels in a specific cancer setting. Listing what was given does not establish a general LL-37 schedule for infections, immunity or wellness. The source context stays attached to the numbers.
A weekly protocol does not establish mixed-vial storage
Timing in a trial describes when treatment was given. It is not a shelf-life study for a separately prepared vial. A calculated supply of several draws does not show that the vial can be kept between them.
Units to dose at 2.50 mg/mL
Mix 5 mg into 2 mL and one U-100 unit carries 25.0 mcg. The table shows how much peptide is in each numbered syringe line. These are conversion examples, not suggested doses.
Open the unit conversion table10 rows
| U-100 line | Volume | Mass (mcg) | Mass (mg) |
|---|---|---|---|
| 10 u | 0.10 mL | 250 mcg | 0.25 mg |
| 20 u | 0.20 mL | 500 mcg | 0.5 mg |
| 30 u | 0.30 mL | 750 mcg | 0.75 mg |
| 40 u | 0.40 mL | 1,000 mcg | 1 mg |
| 50 u | 0.50 mL | 1,250 mcg | 1.25 mg |
| 60 u | 0.60 mL | 1,500 mcg | 1.5 mg |
| 70 u | 0.70 mL | 1,750 mcg | 1.75 mg |
| 80 u | 0.80 mL | 2,000 mcg | 2 mg |
| 90 u | 0.90 mL | 2,250 mcg | 2.25 mg |
| 100 u | 1.00 mL | 2,500 mcg | 2.5 mg |
How the math works
- Concentration — divide the amount entered by the liquid volume used in the calculation: mg ÷ mL = mg/mL. This tells you how many mg are in each mL.
- Volume — the dose divided by that concentration: dose ÷ (mg/mL) = mL.
- Units — on a U-100 syringe one unit is 0.01 mL, so mL × 100 = units. A U-40 unit is 0.025 mL, so the wrong barrel is a 2.5× error. That is why the calculator asks which one you have.
- Rounding gap — the exact draw against the nearest syringe line: |exact − nearest line| ÷ exact × 100 = % difference.
Useful guides for this calculation
The math is only one part of the question. These guides cover the compound, published doses, side effects, mixing steps and supplies.