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Reconstitution · Sermorelin

Sermorelin dosage calculator

Pick the vial, the water you added and the dose. Get the exact draw in units for the syringe in your hand.

Step 1 of 4

  1. How many mg are in your vial?
    Vial amounttotal mg in the calculation
  2. How many mL of water did you add?
  3. What dose do you want to convert?
  4. Which syringe are you using?
Draw to
25.0units

0.25 mL in the syringe · 12 calculated doses from this amount

25.0 units on a U-100 insulin syringe · 1 mL · lines every 2 units, which is 0.25 milliliters. The nearest syringe line is 26 units.

This falls between two syringe lines. The nearest line on this U-100 syringe is 26 units. Open the syringe details below to see the difference.

6 mg ÷ 3 mL = 2.00 mg/mL
→ 20 mcg/unit · 500 mcg = 0.250 mL = 25.0 units

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Show the math and syringe details

Can this syringe show the result clearly?

This draw falls between syringe lines. The exact volume is 25.00 units, but a U-100 syringe has a line every 2 units. Using the nearest line gives 26 units — a 4.0% difference, or 20 mcg.

Want an easier syringe number?

This setup is already easy to read. Changing the water between 0.5 and 3 mL would not put 500 mcg closer to a line on this U-100 syringe.

Adding more water makes the mixture less concentrated, so the same dose uses more syringe units. It does not change how much peptide is in the vial.

This setup is in the address bar — every input is part of the link.

Educational math, not medical advice — dosing decisions belong to a licensed clinician. The available tabs also show supply calculations and any sourced schedule.

How to use the calculator

  1. 1

    Enter the amount in the vial

    Use the total mg printed on your Sermorelin vial.

  2. 2

    Enter the water you added

    Use the amount of water added to that vial, in mL.

  3. 3

    Enter the dose you want to convert

    Choose mg or mcg, then match the result to your syringe.

Sermorelin is the first 29 amino acids of the hormone that prompts growth hormone release. It is the shortest piece that still does the job at the pituitary. Anti-aging and wellness clinics sell it for energy, body composition and sleep.

None of that is what it was approved for. As Geref it was an American medicine for testing pituitary function and for growth failure in children. That product was withdrawn. The one adult study on this page ran 14 days and measured hormone levels, not how anyone looked or felt.

Examples using 6 mg of Sermorelin

Each row uses 6 mg and the liquid volume shown. Dividing the amount by that volume gives the calculated concentration. The rows are arithmetic examples, not alternative product preparations.

◆ How liquid volume changes the resultdose used: 500 mcg

With 2 mL bacteriostatic water

16.7 units

Concentration
3.00 mg/mL
Each U-100 unit
30.0 mcg
Syringe volume
0.167 mL
Nearest line
16 units · 4.0% off

With 3 mL bacteriostatic water

25.0 units

Starting example
Concentration
2.00 mg/mL
Each U-100 unit
20.0 mcg
Syringe volume
0.250 mL
Nearest line
26 units · 4.0% off

The amount, liquid volume and dose shown here are the calculator’s starting example for Sermorelin. Replace them with your own values. Every result in the table is calculated from those inputs.

Drawn from once a week at 500 mcg, a 6 mg vial yields 12 doses — about 12.0 weeks of supply. No storage limit is assigned to this example. Follow the dispensing label for the specific product.

Sermorelin: a different vial strength changes the syringe reading

The sermorelin calculator includes four vial strengths. With the same water volume, each produces a different concentration. The amount entered as the dose can stay the same while the syringe reading changes.

Open the mixing details3 notes

The vial amount is different from the dose

The vial field describes the total amount of sermorelin in the container. The dose field describes the amount used for one calculation. Those fields are not interchangeable, even when both are expressed in milligrams.

At a fixed water volume, a stronger vial gives a more concentrated solution. The same entered dose then takes less volume. Comparing the worked rows shows the effect of vial strength without changing the dose being calculated.

A refill may need a different calculation

A previous syringe reading depends on the vial strength and concentration used to calculate it. If a refill has a different strength, carrying that reading forward can represent a different amount of sermorelin.

The current preparation’s label and instructions are the reference for its strength and concentration. A familiar vial size or an old saved result cannot supply those details for a new preparation. The calculator can show the arithmetic once the inputs are known.

Study amounts need their original context

The page’s study rows describe different uses of sermorelin. Some express the amount per kilogram of body weight; another describes a fixed amount in an adult study. These are separate study records, not steps in one schedule.

An amount per kilogram is not a total dose by itself. Entering it as a flat amount would leave out the weight calculation. The syringe tool converts a total amount and concentration; it does not choose which study amount applies to a person.

Sermorelin test doses and treatment courses answer different questions

The cited records include a pituitary stimulation test, a growth study in children and a short study in older men. Their amounts, routes and schedules serve different purposes. Combining them into one range would lose that context.

Read the supporting evidence3 supporting notes

A stimulation test is a single diagnostic procedure

The test uses an intravenous dose followed by blood sampling. Its purpose is to measure a hormone response. That amount is not a daily treatment instruction and does not describe an ongoing course.

Age and dose basis matter in the treatment studies

The pediatric study used an amount per kilogram, while the older-men study tested fixed amounts. Neither can be read as a universal adult starting dose. The separate reported-practice row remains identified as a report of use.

A syringe line does not choose the schedule

The tool shows how the entered mass fits the selected concentration and syringe. It can reveal a draw between scale marks, but it cannot decide which study population, route or treatment purpose applies to a person.

Units to dose at 2.00 mg/mL

Mix 6 mg into 3 mL and one U-100 unit carries 20.0 mcg. The table shows how much peptide is in each numbered syringe line. These are conversion examples, not suggested doses.

Open the unit conversion table10 rows
Numbered U-100 syringe lines converted to volume and mass at 2.00 milligrams per milliliter.
U-100 lineVolumeMass (mcg)Mass (mg)
10 u0.10 mL200 mcg0.2 mg
20 u0.20 mL400 mcg0.4 mg
30 u0.30 mL600 mcg0.6 mg
40 u0.40 mL800 mcg0.8 mg
50 u0.50 mL1,000 mcg1 mg
60 u0.60 mL1,200 mcg1.2 mg
70 u0.70 mL1,400 mcg1.4 mg
80 u0.80 mL1,600 mcg1.6 mg
90 u0.90 mL1,800 mcg1.8 mg
100 u1.00 mL2,000 mcg2 mg

How the math works

  1. Concentration — divide the amount entered by the liquid volume used in the calculation: mg ÷ mL = mg/mL. This tells you how many mg are in each mL.
  2. Volume — the dose divided by that concentration: dose ÷ (mg/mL) = mL.
  3. Units — on a U-100 syringe one unit is 0.01 mL, so mL × 100 = units. A U-40 unit is 0.025 mL, so the wrong barrel is a 2.5× error. That is why the calculator asks which one you have.
  4. Rounding gap — the exact draw against the nearest syringe line: |exact − nearest line| ÷ exact × 100 = % difference.

Medically reviewed by Kenneth Montecillo, MD2026-09-07open the primary sources

Useful guides for this calculation

The math is only one part of the question. These guides cover the compound, published doses, side effects, mixing steps and supplies.

Sermorelin dosing evidence, without an approved schedule

4 published sermorelin dose values, each linked to the original source.

Sermorelin without an approved label: what exists instead

No published half-life figure was found for sermorelin.

Which sermorelin reactions warrant medical attention

No boxed warning applies to sermorelin, which reflects the review it has not had.

Tesamorelin vs sermorelin, with the sermorelin page in full

What each molecule engages, and what that changes, apart from sermorelin.

Choosing a water volume for a 15 mg sermorelin vial

How the water volume changes concentration, draw size and doses per 15 mg sermorelin vial.

Choosing a water volume for a 5 mg sermorelin vial

How the water volume changes concentration, draw size and doses per 5 mg sermorelin vial.

Questions readers ask

How much water to mix with peptides?

There is no single number, because water sets the concentration rather than the dose. What suits depends on two things: how many milligrams the vial holds, and how many marks you want the dose to cover.

Sermorelin makes that concrete, since it ships in four strengths. Mixed to the same 2 mL, 500 micrograms reads 20 units from a 5 mg vial and 6.7 units from a 15 mg one. Same dose, same water, three times apart.

How much BAC water to reconstitute 10 mg?

10 mg is not one of this page’s four sizes, which are 5, 6, 9 and 15 mg. The arithmetic runs the same: 10 mg in 2 mL is 5 mg/mL, and in 3 mL it is 3.33.

Against 500 micrograms those read 10 and 15 units. Both sit in the readable middle of a U-100 barrel. On that scale a 10 mg vial would slot between the 9 mg and the 15 mg this page does carry.

How much bacteriostatic water do I mix with sermorelin?

2 mL or 3 mL are the volumes here, though the more useful answer is that the water is not what changes between orders. The vial strength is.

Pharmacies fill 6, 9 and 15 mg, and research sellers fill 5 mg. A unit count worked out on one is wrong on the next, and nothing about the new vial announces it. Checking the strength printed on the glass before reusing an old number is the whole defense.

How to reconstitute a 10 mg vial of sermorelin?

Add the water, and each U-100 unit then carries a tenth of the milligrams per milliliter. 10 mg in 3 mL is 3.33 mg/mL, so one unit is 33.3 micrograms and 500 micrograms is 15 units.

That vial would hold 20 draws at 500 micrograms. Worth knowing about the figure itself: it is the low arm of a 14-day study in men of about 68. Only the 1 mg arm of that study raised growth hormone and IGF-I above the men’s own baseline.

4primary sources, each with the day we read it — open the documents used on this page