Pick the vial, the water you added and the dose. Get the exact draw in units for the syringe in your hand.
Draw to25.0units0.25 mL
Step 1 of 4
1How many mg are in your vial?
Vial strengthamount printed on the vial
2How many mL of water did you add?
Bacteriostatic water addedhow much water you added
3What dose do you want to convert?
Target doseenter the dose you want to convert
This vial holds 6,000 mcg in total.
4Which syringe are you using?
Syringe typematch the label on your syringe
U-100 insulin syringe · 1 mL · lines every 2 units · 1 unit = 0.01 mL
Draw to
25.0units
0.25 mL · 2.00 mg/mL · 20 mcg per unit · 12 doses per vial
25.0 units on a U-100 insulin syringe · 1 mL · lines every 2 units, which is 0.25 milliliters. The nearest syringe line is 26 units.
This falls between two syringe lines. The nearest line on this U-100 syringe is 26 units. Open the syringe details below to see the difference.
6 mg ÷ 3 mL = 2.00 mg/mL → 20 mcg/unit · 500 mcg = 0.250 mL =25.0 units
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Show the math and syringe details+
Can this syringe show the result clearly?
This draw falls between syringe lines. The exact volume is 25.00 units, but a U-100 syringe has a line every 2 units. Using the nearest line gives 26 units — a 4.0% difference, or 20 mcg.
Want an easier syringe number?
This setup is already easy to read. Changing the water between 0.5 and 3 mL would not put 500 mcg closer to a line on this U-100 syringe.
Adding more water makes the mixture less concentrated, so the same dose uses more syringe units. It does not change how much peptide is in the vial.
This setup is in the address bar — every input is part of the link.
Educational math, not medical advice — dosing decisions belong to a licensed clinician. The tabs above also plan a schedule week by week and count how many doses one vial holds.
How to use the calculator
STEP 1
Enter the amount in the vial
Use the total amount printed on the vial, in mg.
STEP 2
Enter the water you added
Use the amount of water added to that vial, in mL.
STEP 3
Enter the dose you want to convert
Choose mg or mcg, then match the result to your syringe.
Sermorelin is the first 29 amino acids of the hormone that prompts growth hormone release. It is the shortest piece that still does the job at the pituitary. Anti-aging and wellness clinics sell it for energy, body composition and sleep.
None of that is what it was approved for. As Geref it was an American medicine for testing pituitary function and for growth failure in children. That product was withdrawn. The one adult study on this page ran 14 days and measured hormone levels, not how anyone looked or felt.
Examples using a 6 mg Sermorelin vial
Each row starts with the same 6 mg vial and changes only the amount of water. More water makes the mixture less concentrated, so the same dose uses more syringe units.
◆ How the water amount changes the resultdose used: 500 mcg
For a 6 milligram vial: bacteriostatic water added, resulting concentration, micrograms per U-100 unit, and the draw for a 500 mcg dose.
Water added
Concentration
Per U-100 unit
Draw for 500 mcg
Nearest syringe line
2 mL
3.00 mg/mL
30.0 mcg
16.7 u · 0.167 mL
16 u · 4.0% off
3 mL
2.00 mg/mL
20.0 mcg
25.0 u · 0.250 mL
26 u · 4.0% off
The vial, water and dose shown here are the calculator’s starting example for Sermorelin. Replace them with your own values. Every result in the table is calculated from those inputs.
Drawn from once a week at 500 mcg, a 6 mg vial yields 12 doses — about 12.0 weeks of supply. No cited source says how long the mixed vial keeps, so no storage window is shown.
Four vial sizes, and the next one may not match the last
Sermorelin arrives in more odd strengths than anything else here, because pharmacies fill it rather than a manufacturer. The same dose reads differently on every one of them.
3Open the mixing details — 3 notes
Sizes chosen for a course, not for a product
Four vial sizes are documented. Several appear to be pharmacy-specific fills chosen to cover different treatment lengths rather than standardized manufacturer sizes.
The consequence lands on the barrel. Mix each of them to the same volume of water and one dose reads four different ways, with the extremes several times apart.
The refill is where this bites
The dose in milligrams can stay the same while the vial strength changes between one order and the next. A unit count carried over from the last vial is then simply wrong, and nothing about the new vial announces it.
Checking the strength printed on the glass before reusing an old number is the whole defense. On this compound it is not a formality.
Most of the published amounts scale with weight
The quantities on this page come from trials rather than from current labeling. Most of them scale with body weight, so they do not become a draw on their own.
The one adult study using a flat amount ran two weeks and measured hormone levels. It is real evidence about hormones and no evidence at all about a number to draw to.
This market exists because a medicine left it, and the strengths still show that
Sermorelin was an approved American medicine and then it was not. It came off the market for commercial reasons. The regulator later recorded that the withdrawal was not about safety or about whether it worked. That single finding is why pharmacies may still make it.
4Read the supporting evidence — 4 supporting notes
Two supply chains, and what a research-use label does not settle
A withdrawal for commercial reasons leaves a compounding pathway open. A withdrawal on safety grounds closes it. That is the whole mechanism behind this page carrying pharmacy strengths at all.
One quantity on this page is a test, not a treatment
A pituitary stimulation test uses this peptide to ask whether a gland can respond at all. It is a single push into a vein, in a clinic, scaled to body weight, with blood drawn afterwards.
The default is the arm that moved nothing, and the long course found antibodies
The starting figure comes from a short study in older men. Two amounts were given, twice a day, for two weeks. Only the larger of them raised the hormones being measured above where the men started.
Which pairings land on a syringe line, and which never do
Across this page’s strengths and its two water volumes, some combinations put the draw exactly on a graduation. Others leave the plunger between two marks. The pattern is not random, and it does not follow the water.
Units to dose at 2.00 mg/mL
Mix 6 mg into 3 mL and one U-100 unit carries 20.0 mcg. The table shows how much peptide is in each numbered syringe line. These are conversion examples, not suggested doses.
10Open the unit conversion table — 10 rows
Numbered U-100 syringe lines converted to volume and mass at 2.00 milligrams per milliliter.
U-100 line
Volume
Mass (mcg)
Mass (mg)
10 u
0.10 mL
200 mcg
0.2 mg
20 u
0.20 mL
400 mcg
0.4 mg
30 u
0.30 mL
600 mcg
0.6 mg
40 u
0.40 mL
800 mcg
0.8 mg
50 u
0.50 mL
1,000 mcg
1 mg
60 u
0.60 mL
1,200 mcg
1.2 mg
70 u
0.70 mL
1,400 mcg
1.4 mg
80 u
0.80 mL
1,600 mcg
1.6 mg
90 u
0.90 mL
1,800 mcg
1.8 mg
100 u
1.00 mL
2,000 mcg
2 mg
How the math works
Concentration — divide the amount in the vial by the water you added: mg ÷ mL = mg/mL. This tells you how many mg are in each mL.
Volume — the dose divided by that concentration: dose ÷ (mg/mL) = mL.
Units — on a U-100 syringe one unit is 0.01 mL, so mL × 100 = units. A U-40 unit is 0.025 mL, so the wrong barrel is a 2.5× error. That is why the calculator asks which one you have.
Rounding gap — the exact draw against the nearest syringe line: |exact − nearest line| ÷ exact × 100 = % difference.
Medically reviewed by Jennifer Montecillo, MD · non-practicing medical reviewer·Reviewed 2026-08-12·open the primary sources
Useful guides for this calculation
The math is only one part of the question. These guides cover the compound, published doses, side effects, mixing steps and supplies.
There is no single number, because water sets the concentration rather than the dose. What suits depends on two things: how many milligrams the vial holds, and how many marks you want the dose to cover.
Sermorelin makes that concrete, since it ships in four strengths. Mixed to the same 2 mL, 500 micrograms reads 20 units from a 5 mg vial and 6.7 units from a 15 mg one. Same dose, same water, three times apart.
How much BAC water to reconstitute 10 mg?
10 mg is not one of this page’s four sizes, which are 5, 6, 9 and 15 mg. The arithmetic runs the same: 10 mg in 2 mL is 5 mg/mL, and in 3 mL it is 3.33.
Against 500 micrograms those read 10 and 15 units. Both sit in the readable middle of a U-100 barrel. On that scale a 10 mg vial would slot between the 9 mg and the 15 mg this page does carry.
How much bacteriostatic water do I mix with sermorelin?
2 mL or 3 mL are the volumes here, though the more useful answer is that the water is not what changes between orders. The vial strength is.
Pharmacies fill 6, 9 and 15 mg, and research sellers fill 5 mg. A unit count worked out on one is wrong on the next, and nothing about the new vial announces it. Checking the strength printed on the glass before reusing an old number is the whole defense.
How to reconstitute a 10 mg vial of sermorelin?
Add the water, and each U-100 unit then carries a tenth of the milligrams per milliliter. 10 mg in 3 mL is 3.33 mg/mL, so one unit is 33.3 micrograms and 500 micrograms is 15 units.
That vial would hold 20 draws at 500 micrograms. Worth knowing about the figure itself: it is the low arm of a 14-day study in men of about 68. Only the 1 mg arm of that study raised growth hormone and IGF-I above the men’s own baseline.
4primary sources, each with the day we read it — open the documents used on this page